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Published in: Indian Journal of Surgical Oncology 1/2019

01-03-2019 | Original Article

Prognostic Value of Metastatic Lymph Node Ratio in Pancreatic Cancer

Authors: Can A. Karaca, Ahmet Coker

Published in: Indian Journal of Surgical Oncology | Issue 1/2019

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Abstract

Lymph node involvement in pancreatic adenocancer is one of the strongest predictors of prognosis. However, the extent of lymph node dissection is still a matter of debate and number of dissected nodes varies widely among patients. In order to homogenize this diverse group of patients and more accurately predict their prognosis, we aimed to analyze the effect of metastatic lymph node ratio as an independent prognostic factor. We retrospectively analyzed medical recordings of 326 patients with pancreatic cancer who were treated in a tertiary medical oncology center over a 10-year period. Both in univariate and multivariate analyses, metastatic lymph node ratio proved to be a strong predictor of prognosis which was unaffected from heterogeneity of our patient population and can be used to facilitate predict prognosis of patients who underwent lymph node dissection to various extents and with future studies it can emerge as a successful tool for creating prognostic subgroups of the disease.
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Metadata
Title
Prognostic Value of Metastatic Lymph Node Ratio in Pancreatic Cancer
Authors
Can A. Karaca
Ahmet Coker
Publication date
01-03-2019
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 1/2019
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-018-0824-9

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