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01-10-2010

Prognostic Significance of Host- and Tumor-related Factors in Patients with Gastric Cancer

Authors: Christof Hottenrott, Christos Katsios

Published in: World Journal of Surgery | Issue 10/2010

Excerpt

Several clinicopathologic features have been found to influence survival of patients with gastric cancer. Of these, tumor depth (T), nodal status (N), tumor location (cardia, noncardia), histological type according to the Lauren classification (intestinal, diffuse type), age, type of resection (R0, R1/2), and extent of lymphadenectomy (D2) have been recognized as standard prognostic factors in potentially curable gastric cancer. All these factors are considered in the decision for or against recommending adjuvant chemotherapy. But this decision is suboptimal, particularly in patients with early-stage disease because some of them could avoid adjuvant chemotherapy, whereas others who do not receive such a treatment might benefit from the systemic therapy. Research efforts are underway to identify either additional traditional risk factors or new prognostic and predictive biomarkers based on cancer genetics, genomics, and epigenetics. …

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Title: Prognostic Significance of Host- and Tumor-related Factors in Patients with Gastric Cancer
Authors: Christof Hottenrott
Christos Katsios
Publication date: 01-10-2010
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 10/2010
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-010-0554-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prognostic Significance of Host- and Tumor-related Factors in Patients with Gastric Cancer

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

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