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Published in: Pituitary 2/2018

01-04-2018

Prognostic factors of regrowth in nonfunctioning pituitary tumors

Authors: Gerald Raverot, Alexandre Vasiljevic, Emmanuel Jouanneau

Published in: Pituitary | Issue 2/2018

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Abstract

Surgery is the treatment of choice for nonfunctioning pituitary tumors (NFPTs). Postoperative tumor regrowth during follow-up is present in about half of the patients with invasive NFPTs with residual tumor but occurs also in 15% of patient without residue. Therapeutic strategies should consider this risk of recurrence and the potential side effects associated with therapeutic options. Identification of prognostic markers is mandatory to help clinicians to predict the risk of recurrence and to choose the best strategy between conservative follow-up, second surgery, postoperative adjuvant radiation therapy, and medical treatment (dopamine agonists, somatostatin analogs). Recent advances in pathological classification may be the first step for identification of NFPTs with a high risk of recurrence.
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Metadata
Title
Prognostic factors of regrowth in nonfunctioning pituitary tumors
Authors
Gerald Raverot
Alexandre Vasiljevic
Emmanuel Jouanneau
Publication date
01-04-2018
Publisher
Springer US
Published in
Pituitary / Issue 2/2018
Print ISSN: 1386-341X
Electronic ISSN: 1573-7403
DOI
https://doi.org/10.1007/s11102-017-0861-3

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