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World Journal of Urology

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01-03-2018 | Original Article

Prognostic factors in patients with penile cancer after surgical management

Authors: Shuguang Wen, Wenbiao Ren, Bichen Xue, Yi Fan, Yongjun Jiang, Chunming Zeng, Yujia Li, Xiongbing Zu

Published in: World Journal of Urology | Issue 3/2018

Abstract

Purpose

To examine the possible prognostic factors in patients with penile cancer after surgical management and to identify the independent predictive factors of the prognosis.

Materials and methods

Clinical data of 135 patients with penile cancer who underwent surgical management in two medical centers were collected. Follow-up data were available for 103 patients. Possible prognostic factors including patient’s age; smoking or not; course of disease; phimosis or not; type of surgery; tumor stage; nodal stage; tumor grade and pathological lymph nodes metastasis were retrospectively analyzed by univariate and multivariate analyses with Cox regression.

Results

Five-year cancer-specific survival (CSS) and 1-year CSS were 88.5 and 98.1%, respectively. Univariate Cox analysis revealed that nodal stage and pathological lymph nodes metastasis were significant prognostic factors. Multivariate Cox analysis revealed pathological lymph nodes metastasis was the independent predictive factor of the prognosis.

Conclusion

Pathological lymph nodes metastasis is the independent predictive factor worsening the prognosis in patients with penile cancer.

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Title: Prognostic factors in patients with penile cancer after surgical management
Authors: Shuguang Wen
Wenbiao Ren
Bichen Xue
Yi Fan
Yongjun Jiang
Chunming Zeng
Yujia Li
Xiongbing Zu
Publication date: 01-03-2018
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 3/2018
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-017-2167-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prognostic factors in patients with penile cancer after surgical management

Abstract

Purpose

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

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