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BMC Cancer
Published in: BMC Cancer 1/2021

Open Access 01-12-2021 | Probiotics | Review

Gut microbiome and its role in colorectal cancer

Author: Martina Rebersek

Published in: BMC Cancer | Issue 1/2021

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Abstract

Colorectal cancer (CRC) is still one of the most common types of cancer in the world, and the gut microbiome plays an important role in its development. The microbiome is involved in the carcinogenesis, formation and progression of CRC as well as its response to different systemic therapies. The composition of bacterial strains and the influence of geography, race, sex, and diet on the composition of the microbiome serve as important information for screening, early detection and prediction of the treatment outcome of CRC.
Microbiome modulation is one of the most prospective new strategies in medicine to improve the health of individuals. Therefore, future research and clinical trials on the gut microbiome in oncology as well as in the treatment of CRC patients are warranted to determine the efficacy of systemic treatments for CRC, minimize adverse effects and increase survival rates.
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Metadata
Title
Gut microbiome and its role in colorectal cancer
Author
Martina Rebersek
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Cancer / Issue 1/2021
Electronic ISSN: 1471-2407
DOI
https://doi.org/10.1186/s12885-021-09054-2

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