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01-12-2019 | Sine qua non Clinicopathologic Correlation

Primary Nasopharyngeal Kaposi Sarcoma as Index Diagnosis of AIDS in a Previously Healthy Man

Authors: Gwyneth S. T. Soon, Fredrik Petersson, Mark K. T. Thong, Char Loo Tan

Published in: Head and Neck Pathology | Issue 4/2019

Abstract

A 38-year-old, previously healthy man presented with blood-stained saliva and epistaxis. A 3 mm nasopharyngeal lesion was found. A biopsy was performed and microscopic examination revealed a Kaposi sarcoma. The patient was subsequently found to be positive for human immunodeficiency virus (HIV). The diagnosis of Kaposi sarcoma in the presence of HIV infection advanced his disease to Acquired Immunodeficiency Syndrome (AIDS). Primary manifestation of Kaposi sarcoma in the nasopharynx is extremely rare. The histologic differential diagnosis of Kaposi sarcoma in this unusual site, especially without the clinical history of immunosuppression, is broad. Awareness that nasopharynx can be a primary involvement site of Kaposi sarcoma and serves as index diagnosis of AIDS is important given its serious clinical implication.

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Title: Primary Nasopharyngeal Kaposi Sarcoma as Index Diagnosis of AIDS in a Previously Healthy Man
Authors: Gwyneth S. T. Soon
Fredrik Petersson
Mark K. T. Thong
Char Loo Tan
Publication date: 01-12-2019
Publisher: Springer US
Published in: Head and Neck Pathology / Issue 4/2019
Electronic ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-018-0954-y

At a glance: The STEP trials

Springer Medicine

Primary Nasopharyngeal Kaposi Sarcoma as Index Diagnosis of AIDS in a Previously Healthy Man

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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