Skip to main content
Top
Published in: Journal of Gastrointestinal Cancer 1-2/2009

01-06-2009

Primary Gastric Leiomyosarcoma in Young Revealed by a Massive Hematemesis

Authors: Mehdi Soufi, Abdelkader Errougani, Rachid M. Chekkof

Published in: Journal of Gastrointestinal Cancer | Issue 1-2/2009

Login to get access

Abstract

Introduction

Leiomyosarcomas are one of the most common soft tissue sarcomas, usually seen in deep, soft tissues of the extremities and retroperitoneum. Leiomyosarcoma primarily involving the gastrointestinal tract is uncommon. We present here a rare case of gastric leiomyosarcoma revealed by a massive hematemesis in a young woman.

Case Report

We present a case of primary gastric leiomyosarcoma in a 16-year-old woman who presented with massive hematemesis. Computed tomography scan examination revealed a tumor mass located in the anterior wall of the upper body and protruding into the lumen. The patient was treated by subtotal gastrectomy. The histological examination confirmed the diagnosis of leiomyosarcoma of the stomach.

Discussion

Primary stomach leiomyosarcoma is rare, accounting for only 1% of gastric tumors. Endoscopic ultrasound and biopsy are helpful in establishing the diagnosis. Surgical resection is the treatment of choice for gastric leiomyosarcomas.
Literature
2.
go back to reference DeVita VT Jr, Hellman S, Rosenberg SA. Cancer: principles and practice of oncology. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 1841–91. DeVita VT Jr, Hellman S, Rosenberg SA. Cancer: principles and practice of oncology. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 1841–91.
3.
go back to reference Beyrouti MI, Beyrouti R, Ben Amar M, Frikha F, Abid M, Affes N, et al. Gastric sarcoma. Presse Med. 2008;37:60–6.CrossRef Beyrouti MI, Beyrouti R, Ben Amar M, Frikha F, Abid M, Affes N, et al. Gastric sarcoma. Presse Med. 2008;37:60–6.CrossRef
4.
go back to reference Biswas M, Rahi R, Tiwary SK, Khanna AK, Khanna R. Leiomyosarcoma of stomach: a case report. Kathmandu Univ Med J (KUMJ). 2006;4:510–2. Biswas M, Rahi R, Tiwary SK, Khanna AK, Khanna R. Leiomyosarcoma of stomach: a case report. Kathmandu Univ Med J (KUMJ). 2006;4:510–2.
5.
go back to reference Palazzo L, Landi B, Cellier C, Cuillerier E, Roseau G, Barbier JP. Endosonographic features predictive of benign and malignant gastrointestinal stromal cell tumours. Gut. 2000;46:88–92.PubMedCrossRef Palazzo L, Landi B, Cellier C, Cuillerier E, Roseau G, Barbier JP. Endosonographic features predictive of benign and malignant gastrointestinal stromal cell tumours. Gut. 2000;46:88–92.PubMedCrossRef
6.
go back to reference Machado-Aranda D, Malamet M, Chang YJ, Jacobs MJ, Ferguson L, Silapaswan S, et al. Prevalence and management of gastrointestinal stromal tumors. Am Surg. 2009;75(1):55–60.PubMed Machado-Aranda D, Malamet M, Chang YJ, Jacobs MJ, Ferguson L, Silapaswan S, et al. Prevalence and management of gastrointestinal stromal tumors. Am Surg. 2009;75(1):55–60.PubMed
7.
go back to reference Stavorsky M, Morag B, Stavrosky LT, Papo J. Smooth muscle tumors of the alimentary tract. J Surg Oncol. 1983;22:109–14.CrossRef Stavorsky M, Morag B, Stavrosky LT, Papo J. Smooth muscle tumors of the alimentary tract. J Surg Oncol. 1983;22:109–14.CrossRef
8.
go back to reference Shokouh-Amiri MH, Hansen CP, Moesgaard F. Liposarcoma of the stomach. A case report. Acta Chir Scand. 1986;152:389–91.PubMed Shokouh-Amiri MH, Hansen CP, Moesgaard F. Liposarcoma of the stomach. A case report. Acta Chir Scand. 1986;152:389–91.PubMed
9.
go back to reference Carney JA, Sheps SG, Go VLW, et al. The triad of leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N Engl J Med. 1977;296:1517–8.PubMed Carney JA, Sheps SG, Go VLW, et al. The triad of leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N Engl J Med. 1977;296:1517–8.PubMed
10.
go back to reference Zepeda-Gomez S, Nuncio Jf, et al. Gastrointestinal stromal tumours: clinical and pathological analysis of 24 cases. Rev Invest Clin. 2004;56:443–8.PubMed Zepeda-Gomez S, Nuncio Jf, et al. Gastrointestinal stromal tumours: clinical and pathological analysis of 24 cases. Rev Invest Clin. 2004;56:443–8.PubMed
11.
go back to reference Miettinen M, Virolainen M, Sarlomo-Rikala M. Gastrointestinal stromal tumors. Value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J Surg Pathol. 1995;19:207–16.PubMedCrossRef Miettinen M, Virolainen M, Sarlomo-Rikala M. Gastrointestinal stromal tumors. Value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J Surg Pathol. 1995;19:207–16.PubMedCrossRef
12.
go back to reference Hsieh CC, Shih CS, Wu YC, et al. Leiomyosarcoma of the gastric cardia and fundus. Zhonghua Yixue Zazhi. 1999;62:418–24. Hsieh CC, Shih CS, Wu YC, et al. Leiomyosarcoma of the gastric cardia and fundus. Zhonghua Yixue Zazhi. 1999;62:418–24.
13.
go back to reference Ayoola EA, Arab MM, Tadros NM, Ahmed MA, Banzal SS, Abbo HM, et al. Multicentric leiomyosarcoma of the stomach. Saudi J Gastroenterol. 2003;9:79–81.PubMed Ayoola EA, Arab MM, Tadros NM, Ahmed MA, Banzal SS, Abbo HM, et al. Multicentric leiomyosarcoma of the stomach. Saudi J Gastroenterol. 2003;9:79–81.PubMed
14.
go back to reference Seidel RH, Burdick JS. Gastric leiomyosarcoma presenting as a gastric wall abscess American. J Gastroenterol. 1998;93:2241–4. Seidel RH, Burdick JS. Gastric leiomyosarcoma presenting as a gastric wall abscess American. J Gastroenterol. 1998;93:2241–4.
15.
go back to reference Yokota T, Abe Y, Itoh J, Kunori T, Mochizuki M, Asano S, et al. Epithelioid leiomyosarcoma of the stomach: report of a case. Can J Surg. 2000;43:59–61.PubMed Yokota T, Abe Y, Itoh J, Kunori T, Mochizuki M, Asano S, et al. Epithelioid leiomyosarcoma of the stomach: report of a case. Can J Surg. 2000;43:59–61.PubMed
16.
go back to reference Colovic R, Micev M, Zogovic S, Colovic N, Stojkovic M, Masirevic V. Giant epithelioid leiomyosarcoma of the stomach. Srp Arh Celok Lek. 2000;128:104–9.PubMed Colovic R, Micev M, Zogovic S, Colovic N, Stojkovic M, Masirevic V. Giant epithelioid leiomyosarcoma of the stomach. Srp Arh Celok Lek. 2000;128:104–9.PubMed
17.
go back to reference Bruneton JN, Caramella E, Cazenave P, Birtwisle Y, Hericord P, Drouillard J. Gastric leiomyosarcoma: comparative value of barium examinations, ultrasonography and CT scans. Eur J Radiol. 1987;7:160–2.PubMed Bruneton JN, Caramella E, Cazenave P, Birtwisle Y, Hericord P, Drouillard J. Gastric leiomyosarcoma: comparative value of barium examinations, ultrasonography and CT scans. Eur J Radiol. 1987;7:160–2.PubMed
18.
go back to reference Karila-Cohen P, Petit T, Kotobi H, Merran S. Gastric leiomyosarcoma. J Radiol. 2004;85:1993–7.PubMed Karila-Cohen P, Petit T, Kotobi H, Merran S. Gastric leiomyosarcoma. J Radiol. 2004;85:1993–7.PubMed
19.
go back to reference Yasui W, Oda1 N, Ito1 H, Ichiba Y, Tahara E. Myxoid leiomyosarcoma of the stomach: a case report. Jpn J Clin Oncol. 1991;21:447–52. Yasui W, Oda1 N, Ito1 H, Ichiba Y, Tahara E. Myxoid leiomyosarcoma of the stomach: a case report. Jpn J Clin Oncol. 1991;21:447–52.
20.
go back to reference Koga H, Ochlai A, Nakanishi Y, Sasako M, Mizuno S, Kinoshidta T, et al. Evaluation of prognostic factors in gastric leiomyosarcoma. Am J Gastroentrol. 1995;90:1307–12. Koga H, Ochlai A, Nakanishi Y, Sasako M, Mizuno S, Kinoshidta T, et al. Evaluation of prognostic factors in gastric leiomyosarcoma. Am J Gastroentrol. 1995;90:1307–12.
21.
go back to reference Davis GB, Blanchard DK, Hatch GF, WertheimerHatch L, Hatch KF, Foster RS, et al. Tumors of the stomach. World J Surg. 2000;24:41220.CrossRef Davis GB, Blanchard DK, Hatch GF, WertheimerHatch L, Hatch KF, Foster RS, et al. Tumors of the stomach. World J Surg. 2000;24:41220.CrossRef
22.
go back to reference Matthews BD, Walsh RM, Kercher KW, et al. Laparoscopic vs open resection of gastric stromal tumors. Surg Endosc. 2002;16:803–7.PubMedCrossRef Matthews BD, Walsh RM, Kercher KW, et al. Laparoscopic vs open resection of gastric stromal tumors. Surg Endosc. 2002;16:803–7.PubMedCrossRef
23.
go back to reference Hagiwara A, Takahashi T, Lee R, Ueda T, Takeda M, Itoh T. Chemotherapy for carcinomatous peritonitis and pleuritis with MMC-CH, mitomycin C adsorbed on activated carbon particles. Clinical trials. Cancer. 1987;59:245–51.PubMedCrossRef Hagiwara A, Takahashi T, Lee R, Ueda T, Takeda M, Itoh T. Chemotherapy for carcinomatous peritonitis and pleuritis with MMC-CH, mitomycin C adsorbed on activated carbon particles. Clinical trials. Cancer. 1987;59:245–51.PubMedCrossRef
Metadata
Title
Primary Gastric Leiomyosarcoma in Young Revealed by a Massive Hematemesis
Authors
Mehdi Soufi
Abdelkader Errougani
Rachid M. Chekkof
Publication date
01-06-2009
Publisher
Humana Press Inc
Published in
Journal of Gastrointestinal Cancer / Issue 1-2/2009
Print ISSN: 1941-6628
Electronic ISSN: 1941-6636
DOI
https://doi.org/10.1007/s12029-009-9080-0

Other articles of this Issue 1-2/2009

Journal of Gastrointestinal Cancer 1-2/2009 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.