Published in:
Open Access
01-12-2015 | Case report
Primary apocrine sweat gland carcinomas of the axilla: a report of two cases and a review of the literature
Authors:
Min‐Ki Seong, Eun-Kyu Kim, Kanghee Han, Hyesil Seol, Hyun‐Ah Kim, Woo Chul Noh
Published in:
World Journal of Surgical Oncology
|
Issue 1/2015
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Abstract
Primary apocrine sweat gland carcinoma (PASGC) is an extremely rare malignancy with a relatively favorable prognosis. PASGC is often suspected to be a benign disease during an initial clinical examination, which leads to inadequate initial treatment and extensive metastasis. Owing to the limited number of reports on PASGC, its diagnostic criteria and treatment guidelines have not yet been established. The only known curative therapy for localized PASGC is wide local excision. In the present report, we describe two cases of PASGC with locally aggressive disease that arose in the axilla and review the literature about its clinicopathological features, diagnosis, and treatment. Based on the findings of the current report, we suggest that a sentinel lymph node biopsy and adjuvant anti-estrogen therapy should be included in the management of PASGC.