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Published in: Endocrine 1/2013

01-08-2013 | Editorial

Prevention of diabetic foot ulceration: new evidences for an old problem

Author: Luigi Uccioli

Published in: Endocrine | Issue 1/2013

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Excerpt

Diabetic patients have a 15 % lifetime risk of developing a foot ulcer and have a 15 % risk of developing a lower extremity amputation. Amputation is preceded by non-healing foot wounds in 85 % of cases [1]. The ulcerated diabetic foot may be considered the complication of the peripheral neuropathy (PN) and/or peripheral arterial disease (PAD). …
Literature
1.
2.
go back to reference L. Prompers, N. Schaper, J. Apelqvist, M. Edmonds, E. Jude, D. Mauricio, L. Uccioli, V. Urbancic, K. Bakker, P. Holstein, A. Jirkovska, A. Piaggesi, G. Ragnarson-Tennvall, H. Reike, M. Spraul, K. Van Acker, J. Van Baal, F. Van Merode, I. Ferreira, M. Huijberts, Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study. Diabetologia 51, 747–755 (2008)PubMedCrossRef L. Prompers, N. Schaper, J. Apelqvist, M. Edmonds, E. Jude, D. Mauricio, L. Uccioli, V. Urbancic, K. Bakker, P. Holstein, A. Jirkovska, A. Piaggesi, G. Ragnarson-Tennvall, H. Reike, M. Spraul, K. Van Acker, J. Van Baal, F. Van Merode, I. Ferreira, M. Huijberts, Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study. Diabetologia 51, 747–755 (2008)PubMedCrossRef
3.
go back to reference E. D’Ambrogi, L. Giurato, M.A. D’Agostino, C. Giacomozzi, V. Macellari, A. Caselli, U. Uccioli, Contribution of plantar fascia to the increased forefoot pressures in diabetic patients. Diabetes Care 26, 1525–1529 (2003)PubMedCrossRef E. D’Ambrogi, L. Giurato, M.A. D’Agostino, C. Giacomozzi, V. Macellari, A. Caselli, U. Uccioli, Contribution of plantar fascia to the increased forefoot pressures in diabetic patients. Diabetes Care 26, 1525–1529 (2003)PubMedCrossRef
4.
go back to reference N. Singh, D.G. Armstrong, B.A. Lipsky, Preventing foot ulcers in patients with diabetes. JAMA 293, 217–228 (2005)PubMedCrossRef N. Singh, D.G. Armstrong, B.A. Lipsky, Preventing foot ulcers in patients with diabetes. JAMA 293, 217–228 (2005)PubMedCrossRef
5.
go back to reference G.E. Reiber, L. Vileikyte, E.J. Boyko, M. Del Aguila, D.G. Smith, L.A. Lavery, A.J. Boulton, Causal pathways for incident lower-extremity ulcers in patients with diabetes from two settings. Diabetes Care 22, 157–162 (1999)PubMedCrossRef G.E. Reiber, L. Vileikyte, E.J. Boyko, M. Del Aguila, D.G. Smith, L.A. Lavery, A.J. Boulton, Causal pathways for incident lower-extremity ulcers in patients with diabetes from two settings. Diabetes Care 22, 157–162 (1999)PubMedCrossRef
6.
go back to reference L. Uccioli, R. Gandini, L. Giurato, S. Fabiano, E. Pampana, V. Spallone, E. Vainieri, G. Simonetti, Long-term outcomes of diabetic patients with critical limb ischemia followed in a tertiary referral diabetic foot clinic. Diabetes Care 33, 977–982 (2010)PubMedCrossRef L. Uccioli, R. Gandini, L. Giurato, S. Fabiano, E. Pampana, V. Spallone, E. Vainieri, G. Simonetti, Long-term outcomes of diabetic patients with critical limb ischemia followed in a tertiary referral diabetic foot clinic. Diabetes Care 33, 977–982 (2010)PubMedCrossRef
7.
go back to reference A. Moura Neto, D.E. Zantut-Wittmann, T.D. Fernandes, M. Nery, M.C. Parisi, Risk factors for ulceration and amputation in diabetic foot: study in a cohort of 496 patients. Endocrine. 2012 A. Moura Neto, D.E. Zantut-Wittmann, T.D. Fernandes, M. Nery, M.C. Parisi, Risk factors for ulceration and amputation in diabetic foot: study in a cohort of 496 patients. Endocrine. 2012
8.
go back to reference J.L. Richard, L. Reilhes, S. Buvry, M. Goletto, J.L. Faillie, Screening patients at risk for diabetic foot ulceration. A comparison between measurement of vibration perception threshold and 10-g monofilament test. Int. Wound J. 10, 1742–1748 (2012) J.L. Richard, L. Reilhes, S. Buvry, M. Goletto, J.L. Faillie, Screening patients at risk for diabetic foot ulceration. A comparison between measurement of vibration perception threshold and 10-g monofilament test. Int. Wound J. 10, 1742–1748 (2012)
9.
go back to reference M.J. Young, J.L. Breddy, A. Veves, A.J. Boulton, The prediction of diabetic neuropathic foot ulceration using vibration perception thresholds. A prospective study. Diabetes Care 17, 557–560 (1994)PubMedCrossRef M.J. Young, J.L. Breddy, A. Veves, A.J. Boulton, The prediction of diabetic neuropathic foot ulceration using vibration perception thresholds. A prospective study. Diabetes Care 17, 557–560 (1994)PubMedCrossRef
11.
go back to reference J.A.N. Dorresteijn, D.M.W. Kriegsman, W.J.J. Assendelft, G.D. Valk, Patient education for preventing diabetic foot ulceration (review). Cochrane Database Syst. Rev. 10 CD001488, D001488.pub4 (2012). doi:10.1002/14651858 J.A.N. Dorresteijn, D.M.W. Kriegsman, W.J.J. Assendelft, G.D. Valk, Patient education for preventing diabetic foot ulceration (review). Cochrane Database Syst. Rev. 10 CD001488, D001488.pub4 (2012). doi:10.​1002/​14651858
12.
go back to reference M.J. Young, P.R. Cavanagh, G. Thomas, M.M. Johnson, H. Murray, A.J. Boulton, The effect of callus removal on dynamic plantar foot pressures in diabetic patients. Diabet. Med. 9, 55–57 (1992)PubMedCrossRef M.J. Young, P.R. Cavanagh, G. Thomas, M.M. Johnson, H. Murray, A.J. Boulton, The effect of callus removal on dynamic plantar foot pressures in diabetic patients. Diabet. Med. 9, 55–57 (1992)PubMedCrossRef
13.
go back to reference B. Rhim, L. Harkless, Can we stop problems before they arise? Semin. Vasc. Surg. 25, 122–128 (2012)PubMedCrossRef B. Rhim, L. Harkless, Can we stop problems before they arise? Semin. Vasc. Surg. 25, 122–128 (2012)PubMedCrossRef
14.
go back to reference L. Uccioli, C. Giacomozzi, The role of footwear in the prevention of diabetic foot problems. A. Veves, et al., (eds) The diabetic foot: medical and surgical management. Contemporary Diabetes. doi:10.1007.978-1-61779-791-0_26 L. Uccioli, C. Giacomozzi, The role of footwear in the prevention of diabetic foot problems. A. Veves, et al., (eds) The diabetic foot: medical and surgical management. Contemporary Diabetes. doi:10.​1007.​978-1-61779-791-0_​26
15.
go back to reference L. Uccioli, E. Faglia, G. Monticane, F. Favales, L. Durola, A. Alleghi, A. Quarantiello, P. Calia, G. Menzinger, Manufactured shoes in the prevention of diabetic foot ulcers. Diabetes Care 18(10), 1376–1378 (1995)PubMedCrossRef L. Uccioli, E. Faglia, G. Monticane, F. Favales, L. Durola, A. Alleghi, A. Quarantiello, P. Calia, G. Menzinger, Manufactured shoes in the prevention of diabetic foot ulcers. Diabetes Care 18(10), 1376–1378 (1995)PubMedCrossRef
16.
go back to reference L. Rizzo, A. Tedeschi, E. Fallani, A. Coppelli, V. Vallini, E. Iacopi, A. Piaggesi, Custom made orthesis and shoes in a structured follow-up program reduces the incidence of neuropathic ulcers in high-risk diabetic foot patients. Int. J. Low Extrem. Wounds 11, 59–64 (2012)PubMedCrossRef L. Rizzo, A. Tedeschi, E. Fallani, A. Coppelli, V. Vallini, E. Iacopi, A. Piaggesi, Custom made orthesis and shoes in a structured follow-up program reduces the incidence of neuropathic ulcers in high-risk diabetic foot patients. Int. J. Low Extrem. Wounds 11, 59–64 (2012)PubMedCrossRef
Metadata
Title
Prevention of diabetic foot ulceration: new evidences for an old problem
Author
Luigi Uccioli
Publication date
01-08-2013
Publisher
Springer US
Published in
Endocrine / Issue 1/2013
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-013-9929-7

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