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Published in: Virology Journal 1/2012

Open Access 01-12-2012 | Research

Prevalence of human immunodeficiency virus infection among transgender men in Rawalpindi (Pakistan)

Authors: Hashaam Akhtar, Yasmeen Badshah, Samar Akhtar, Naghmana Kanwal, Maha Nadeem Akhtar, Najam us Sahar Sadaf Zaidi, Ishtiaq Qadri

Published in: Virology Journal | Issue 1/2012

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Abstract

Background

Transgender males are at high risk for sexually transmitted diseases including AIDS caused by the notorious Human Immunodeficiency Virus (HIV), yet little consideration is given by the policy makers, researchers and non-governmental organizations (NGOs) towards this sensitive issue in Pakistan.

Methods

In this study, we have investigated the prevalence of HIV infection among 306 transgender males with a median age of 29 years (range 15–64 years) residing in Rawalpindi, Pakistan. Rapid HIV antibody-screening methods including the strip test and Enzyme Linked Immuno-absorbent tests were employed to detect HIV antibodies among the subjects. For further confirmation, Polymerase Chain Reaction (PCR) was carried out. Statistical analytical techniques utilized included logistic regression and chi-square.

Results

HIV-1 was found to be the predominant viral subtype. PCR confirmed 21.6% (Confidence Interval 0.17-0.26) of the respondents were reported being HIV positive. 15.7% of the transgender men who shave at home and 13.7% of the transgender men who were educated below 5th grade were found to have HIV.

Conclusion

This study shows a very high prevalence of HIV among transgender males. Unawareness among these individuals about the ramifications of this infection owes largely to lack of education. The spread rate is alarming and HIV epidemic is imminent if awareness is not widespread.
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Literature
1.
go back to reference Valadas E, Franca L, Sousa S, Antunes F: 20 Years of HIV-2 infection in Portugal: trends and changes in epidemiology. Clin Infect Dis. 2009, 48 (8): 1166-1167.PubMedCrossRef Valadas E, Franca L, Sousa S, Antunes F: 20 Years of HIV-2 infection in Portugal: trends and changes in epidemiology. Clin Infect Dis. 2009, 48 (8): 1166-1167.PubMedCrossRef
3.
go back to reference Elford J, Ibrahim F, Bukutu C, Anderson J: Sexual behaviour of people living with HIV in London: implications for HIV transmission. AIDS. 2007, 21 (suppl 1): S63-S70. 10.1097/01.aids.0000255087.62223.ff.PubMedCrossRef Elford J, Ibrahim F, Bukutu C, Anderson J: Sexual behaviour of people living with HIV in London: implications for HIV transmission. AIDS. 2007, 21 (suppl 1): S63-S70. 10.1097/01.aids.0000255087.62223.ff.PubMedCrossRef
4.
go back to reference Sued O, Miró JM, Alquezar A, Claramonte X, García F, Plana M, Arnedo M, De Lazzari E, Gil C, Manzardo C, Blanco JL, Martínez E, Mallolas J, Joseph J, Pumarola T, Gallart T, Gatell JM: Primary human immunodeficiency virus type 1 infection: clinical, virological and immunological characteristics of 75 patients (1997–2003). EnfermInfeccMicrobiolClin. 2006, 24: 238-244. Sued O, Miró JM, Alquezar A, Claramonte X, García F, Plana M, Arnedo M, De Lazzari E, Gil C, Manzardo C, Blanco JL, Martínez E, Mallolas J, Joseph J, Pumarola T, Gallart T, Gatell JM: Primary human immunodeficiency virus type 1 infection: clinical, virological and immunological characteristics of 75 patients (1997–2003). EnfermInfeccMicrobiolClin. 2006, 24: 238-244.
5.
go back to reference Diaz T, Vlahov D, Greenberg B, Cuevas Y, Garfein R: Sexual orientation and HIV infection prevalence among young Latino injection drug users in Harlem. J Womens Health Gend Based Med. 2001, 10: 371-380. 10.1089/152460901750269698.PubMedCrossRef Diaz T, Vlahov D, Greenberg B, Cuevas Y, Garfein R: Sexual orientation and HIV infection prevalence among young Latino injection drug users in Harlem. J Womens Health Gend Based Med. 2001, 10: 371-380. 10.1089/152460901750269698.PubMedCrossRef
6.
go back to reference Khanani RM, Hafeez A, Rab SM, Rasheed S: Human immunodeficiency virus-associated disorders in Pakistan. AIDS Res Hum Retroviruses. 1988, 4: 149-154. 10.1089/aid.1988.4.149.PubMedCrossRef Khanani RM, Hafeez A, Rab SM, Rasheed S: Human immunodeficiency virus-associated disorders in Pakistan. AIDS Res Hum Retroviruses. 1988, 4: 149-154. 10.1089/aid.1988.4.149.PubMedCrossRef
7.
go back to reference Abdul Mujeeb S, Hashmi MR: A study of HIV-antibody sera of blood donors and people at risk. J Pak Med Assoc. 1988, 38: 221-222.PubMed Abdul Mujeeb S, Hashmi MR: A study of HIV-antibody sera of blood donors and people at risk. J Pak Med Assoc. 1988, 38: 221-222.PubMed
8.
go back to reference Khan OA, Hyder AA: Responses to an emerging threat: HIV/AIDS policy in Pakistan. Health Policy Plan. 2001, 16: 214-218. 10.1093/heapol/16.2.214.PubMedCrossRef Khan OA, Hyder AA: Responses to an emerging threat: HIV/AIDS policy in Pakistan. Health Policy Plan. 2001, 16: 214-218. 10.1093/heapol/16.2.214.PubMedCrossRef
10.
go back to reference Hawkes S, Collumbien M, Platt L, Lalji N, Rizvi N, Andreasen A, Chow J, Muzaffar R, Ur-Rehman H, Siddiqui N, Hasan S, Bokhari A: HIV and other sexually transmitted infections among men, transgenders and women selling sex in two cities in Pakistan: a cross-sectional prevalence survey. SexTransm Infect. 2009, 85: ii8-ii16. Hawkes S, Collumbien M, Platt L, Lalji N, Rizvi N, Andreasen A, Chow J, Muzaffar R, Ur-Rehman H, Siddiqui N, Hasan S, Bokhari A: HIV and other sexually transmitted infections among men, transgenders and women selling sex in two cities in Pakistan: a cross-sectional prevalence survey. SexTransm Infect. 2009, 85: ii8-ii16.
11.
go back to reference Altaf A, Emannuel F, Archibald C, Baloch C, Uzma Q, Mehmood A: Behavioral characteristics of male and eunuch (hijra) sex workers in Karachi, Pakistan. Abstract CDC0439. 2006, Toronto: XVI International AIDS Conference 2006 13–18 August Altaf A, Emannuel F, Archibald C, Baloch C, Uzma Q, Mehmood A: Behavioral characteristics of male and eunuch (hijra) sex workers in Karachi, Pakistan. Abstract CDC0439. 2006, Toronto: XVI International AIDS Conference 2006 13–18 August
12.
go back to reference SPSS 16.0 for Windows. 2008, Chicago: SPSS Inc, Release 16.0.2. SPSS 16.0 for Windows. 2008, Chicago: SPSS Inc, Release 16.0.2.
13.
go back to reference Herek GM, Capitanio JP, Widaman KF: HIV-related stigma and knowledge in the United States: prevalence and trends, 1991–1999. Am J Public Health. 2002, 92 (3): 371-377. 10.2105/AJPH.92.3.371.PubMedPubMedCentralCrossRef Herek GM, Capitanio JP, Widaman KF: HIV-related stigma and knowledge in the United States: prevalence and trends, 1991–1999. Am J Public Health. 2002, 92 (3): 371-377. 10.2105/AJPH.92.3.371.PubMedPubMedCentralCrossRef
14.
go back to reference Vittinghoff E, Douglas J, Judson F, et al: Per-contact risk of human immuno-deficiency virus transmission between male sexual partners. Am J Epidemiol. 1999, 150 (3): 306-311. 10.1093/oxfordjournals.aje.a010003.PubMedCrossRef Vittinghoff E, Douglas J, Judson F, et al: Per-contact risk of human immuno-deficiency virus transmission between male sexual partners. Am J Epidemiol. 1999, 150 (3): 306-311. 10.1093/oxfordjournals.aje.a010003.PubMedCrossRef
15.
go back to reference Fengyi J, James J, Matthew L, Garrett P, Iryna Z, et al: Per-contact probability of HIV transmission in homosexual men in Sydney in the era of HAART. AIDS. 2010, 24: 907-913. 10.1097/QAD.0b013e3283372d90.CrossRef Fengyi J, James J, Matthew L, Garrett P, Iryna Z, et al: Per-contact probability of HIV transmission in homosexual men in Sydney in the era of HAART. AIDS. 2010, 24: 907-913. 10.1097/QAD.0b013e3283372d90.CrossRef
16.
go back to reference Baba TW, Trichel AM, An L, et al: Infection and AIDS in adult macaques after non-traumatic oral exposure to cell-free SIV. Science. 1996, 272 (5267): 1486-1489. 10.1126/science.272.5267.1486.PubMedCrossRef Baba TW, Trichel AM, An L, et al: Infection and AIDS in adult macaques after non-traumatic oral exposure to cell-free SIV. Science. 1996, 272 (5267): 1486-1489. 10.1126/science.272.5267.1486.PubMedCrossRef
17.
go back to reference Waheed Y, Saeed U, Safi S, Chaudhry NW, Qadri I: Awareness and risk factors associated with barbers in transmission of hepatitis B and C from Pakistani population: barber’s role in viral transmission. Asian Biomed. 2010, 4: 435-442. Waheed Y, Saeed U, Safi S, Chaudhry NW, Qadri I: Awareness and risk factors associated with barbers in transmission of hepatitis B and C from Pakistani population: barber’s role in viral transmission. Asian Biomed. 2010, 4: 435-442.
18.
go back to reference Laxmi T, Gauri S, Payal K, Revati , Priya B, Jeeva R, Amitava S, Agniva L, Anindya H, Laxmi B, Pramod , Simran S, et al: Transgender - hijra strategy. 2011, Mumbai, India: NACP IV working groups, Version: 1.0 Laxmi T, Gauri S, Payal K, Revati , Priya B, Jeeva R, Amitava S, Agniva L, Anindya H, Laxmi B, Pramod , Simran S, et al: Transgender - hijra strategy. 2011, Mumbai, India: NACP IV working groups, Version: 1.0
20.
go back to reference Office of the Surgeon General: The surgeon general’s call to action to promote sexual health and responsible sexual behavior, July 9. 2001 Office of the Surgeon General: The surgeon general’s call to action to promote sexual health and responsible sexual behavior, July 9. 2001
21.
go back to reference Des Jarlais DC, Friedman SR, Choopanya K, Vanichseni S, Ward TP: International epidemiology of HIV and AIDS among injecting drug users. AIDS. 1992, 6: 1053-1068. 10.1097/00002030-199210000-00001.PubMedCrossRef Des Jarlais DC, Friedman SR, Choopanya K, Vanichseni S, Ward TP: International epidemiology of HIV and AIDS among injecting drug users. AIDS. 1992, 6: 1053-1068. 10.1097/00002030-199210000-00001.PubMedCrossRef
22.
go back to reference Operario D, Toho S, Underhill K: Sex work and HIV status among transgender women: systematic review and meta-analysis. J Acquir Immune DeficSyndr. 2008, 48 (1): 97-103. 10.1097/QAI.0b013e31816e3971.CrossRef Operario D, Toho S, Underhill K: Sex work and HIV status among transgender women: systematic review and meta-analysis. J Acquir Immune DeficSyndr. 2008, 48 (1): 97-103. 10.1097/QAI.0b013e31816e3971.CrossRef
Metadata
Title
Prevalence of human immunodeficiency virus infection among transgender men in Rawalpindi (Pakistan)
Authors
Hashaam Akhtar
Yasmeen Badshah
Samar Akhtar
Naghmana Kanwal
Maha Nadeem Akhtar
Najam us Sahar Sadaf Zaidi
Ishtiaq Qadri
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2012
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/1743-422X-9-229

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