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Published in: Virology Journal 1/2011

Open Access 01-12-2011 | Research

Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV

Authors: Najib U Khan, Ijaz Ali, Naeem U Ahmad, Aqib Iqbal, Latif U Rehman, Iqbal Munir, Muti U Rehman, Sanaullah Khan, Sajid Ali, Lubna Siddique, Zahoor A Swati

Published in: Virology Journal | Issue 1/2011

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Abstract

Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by ICT (Immuno-chromatographic test), ELISA and RT-PCR. Out of the 7148 blood donors, 224 (3.13%) were positive for anti-HCV antibodies by ICT, 135 (1.89%) by ELISA while 118 (1.65%) blood donors had active HCV infection as detected by RT-PCR. We suggest that ELISA should be used for anti-HCV screening in public sector hospitals and health care units.
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Metadata
Title
Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
Authors
Najib U Khan
Ijaz Ali
Naeem U Ahmad
Aqib Iqbal
Latif U Rehman
Iqbal Munir
Muti U Rehman
Sanaullah Khan
Sajid Ali
Lubna Siddique
Zahoor A Swati
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2011
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/1743-422X-8-154

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