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08-12-2022 | Original Article

Prevalence and trends of hyperuricemia among adults over 40 years old in an economically developed region of China from 2017 to 2020

Authors: Feng-Jun Du, Yue-Qing Huang, Ren-Fang Han, Min Huang, Zhen-Yu Jia, Hong-Ming Shen, Jian-Jun Yao, Han Min, Chun-Hua Zhao

Published in: Journal of Public Health | Issue 1/2024

Abstract

Aim

Hyperuricemia-related investigations in economically developed areas of China are limited and outdated. The aim of this study was to evaluate the prevalence and trends of hyperuricemia in adults over 40 years of age between 2017 and 2020.

Subject and methods

The data was obtained from the Huangqiao Chronic Diseases Study. A total of 7161, 6368, 8465, and 5968 individuals participated in the Huangqiao Chronic Diseases Study from 2017 to 2020, respectively. Hyperuricemia was defined as a serum urate level of >7.0 mg/dL for men and > 6.0 mg/dL for women. A generalized estimation equation (GEE) was adopted to test the trends of hyperuricemia prevalence among adults.

Results

Crude, age-standardized hyperuricemia prevalence rates were 37.10% and 36.47%, respectively, in adults over 40 years old in 2020. Females had a lower risk of having hyperuricemia [adjusted odds ratio (AOR) 0.87; 95% confidence interval (CI) 0.78–0.98]. As the participant’s age increased by 10-year increments, the risk of having hyperuricemia also increased (AOR 1.20; 95% CI 1.13–1.28). Participants with hypertriglyceridemia had a greater risk of having hyperuricemia (AOR 2.20; 95% CI 1.96–2.47). Participants with overweight and obesity had a greater risk of having hyperuricemia (AOR 1.87; 95% CI 1.65–2.11 and AOR 3.33; 95% CI 2.82–3.93, respectively). The prevalence of hyperuricemia has increased by 16.13% in the past four years. Trend analysis revealed a serious annual upward trend from 2017 to 2020 [odds ratio (OR) 1.33; 95% CI 1.30–1.35].

Conclusion

Hyperuricemia is highly prevalent in adults aged over 40 years in economically developed regions in eastern China. A serious and continuous upward trend in the prevalence of hyperuricemia is observed. Prevention and control strategies for hyperuricemia are urgently needed.

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Title: Prevalence and trends of hyperuricemia among adults over 40 years old in an economically developed region of China from 2017 to 2020
Authors: Feng-Jun Du
Yue-Qing Huang
Ren-Fang Han
Min Huang
Zhen-Yu Jia
Hong-Ming Shen
Jian-Jun Yao
Han Min
Chun-Hua Zhao
Publication date: 08-12-2022
Publisher: Springer Berlin Heidelberg
Published in: Journal of Public Health / Issue 1/2024
Print ISSN: 2198-1833
Electronic ISSN: 1613-2238
DOI: https://doi.org/10.1007/s10389-022-01787-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prevalence and trends of hyperuricemia among adults over 40 years old in an economically developed region of China from 2017 to 2020

Abstract

Aim

Subject and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Aim

Subject and methods

Results

Conclusion

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