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Published in: World Journal of Surgical Oncology 1/2012

Open Access 01-12-2012 | Case report

Presentation of two patients with malignant granulosa cell tumors, with a review of the literature

Authors: Ryousuke Tamura, Yoshihito Yokoyama, Takeshi Yanagita, Yukiko Matsumura, Kazuhiro Abe, Ryousuke Taniguchi, Hideki Mizunuma

Published in: World Journal of Surgical Oncology | Issue 1/2012

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Abstract

Granulosa cell tumors (GCTs) of the ovary account for 2 to 5 of ovarian malignancies. We present two patients with malignant ovarian adult GCT. In one patient, a combination of bleomycin, etoposide, and cisplatin was effective after initial surgery for malignant GCT. In the other, an aromatase inhibitor was effective for recurrent malignant GCT. We also review the literature for further management of this tumor. Because GCT of the ovary is rare, it will be necessary to elucidate the clinical phenotype and establish treatment protocols by accumulating and analyzing more patients.
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Metadata
Title
Presentation of two patients with malignant granulosa cell tumors, with a review of the literature
Authors
Ryousuke Tamura
Yoshihito Yokoyama
Takeshi Yanagita
Yukiko Matsumura
Kazuhiro Abe
Ryousuke Taniguchi
Hideki Mizunuma
Publication date
01-12-2012
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2012
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-10-185

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