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European Archives of Oto-Rhino-Laryngology

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02-11-2023 | Premature Birth | Laryngology

Profiling the clinical characteristics and surgical efficacy of laryngomalacia in children

Authors: Ling Xiao, Yang Yang, Ling Ding, Zhihai Zhang, Xuelei Li, Hongbing Yao, Xinye Tang

Published in: European Archives of Oto-Rhino-Laryngology | Issue 1/2024

Abstract

Objective

To analyze the clinical characteristics of laryngomalacia in Chinese children and explore the surgical efficacy and factors influencing severe laryngomalacia.

Methods

Children (0–18 years) diagnosed with laryngomalacia in our hospital from January 2016 to January 2022 were enrolled in this study. Clinical data of patients, including general conditions, clinical symptoms, grading and classification, medical comorbidities, surgical efficacy, and the risk factors influencing severe laryngomalacia were retrospectively analyzed.

Results

A total of 1810 children were enrolled (male:female; 2.02:1), among which most were infants under 1 year (77.18%). Inspiratory laryngeal stridor (69.56%) was the most common symptom. Most patients had mild laryngomalacia (79.28%), with type IV laryngomalacia being the most common classification (52.27%). Congenital heart disease (37.85%) was the most common medical comorbidity. A total of 168 severe laryngomalacia cases were treated via supraglottoplasty with an effective rate of 83.93%. Notably, preterm birth (OR = 3.868, 95% CI 1.340 ~ 11.168), low birth weight (OR = 4.517, 95% CI 1.477 ~ 13.819) and medical comorbidities (OR = 7.219, 95% CI 2.534 ~ 20.564) were independent risk factors for poor prognosis (P < 0.05).

Conclusion

Laryngomalacia is common among infants under the age of one, and it is mostly characterized by inspiratory laryngeal stridor with various medical comorbidity. Supraglottoplasty is the first treatment choice for severe laryngomalacia cases with high success rates. However, premature delivery, low birth weight, and medical comorbidities significantly affect the efficacy of surgery.

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Title: Profiling the clinical characteristics and surgical efficacy of laryngomalacia in children
Authors: Ling Xiao
Yang Yang
Ling Ding
Zhihai Zhang
Xuelei Li
Hongbing Yao
Xinye Tang
Publication date: 02-11-2023
Publisher: Springer Berlin Heidelberg
Keyword: Premature Birth
Published in: European Archives of Oto-Rhino-Laryngology / Issue 1/2024
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08254-9

2024 ASCO Annual Meeting

Springer Medicine

Profiling the clinical characteristics and surgical efficacy of laryngomalacia in children

Abstract

Objective

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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