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Published in: Journal of Nephrology 6/2017

01-12-2017 | Review

Pregnancy-related acute kidney injury in high income countries: still a critical issue

Authors: Fadi Fakhouri, Clément Deltombe

Published in: Journal of Nephrology | Issue 6/2017

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Abstract

The rate of pregnancy-associated acute kidney injury (P-AKI) has dwindled in high income countries mainly following the legalization of abortion in the seventies and early eighties and the general improvement in obstetrical care. P-AKI has not however disappeared from high income countries and several reports indicate that its frequency has even increased during the last decade. The reasons for such evolution are probably an improved surveillance and reporting of P-AKI and a more aggressive approach to the treatment of pregnancy complications, with unintended renal side effects. The characteristics of pregnant women in high-income countries have also changed as the number of women with medical conditions, including diabetes and chronic kidney disease, has tended to increase. P-AKI in high income countries is still a matter of concern for nephrologists who have in mind that any rate, however low, of P-AKI remains unacceptable.
Literature
1.
go back to reference Stratta P, Besso L, Canavese C et al (1996) Is pregnancy-related acute renal failure a disappearing clinical entity? Ren Fail 18(4):575 – 84CrossRef Stratta P, Besso L, Canavese C et al (1996) Is pregnancy-related acute renal failure a disappearing clinical entity? Ren Fail 18(4):575 – 84CrossRef
2.
go back to reference Grunfeld JP, Pertuiset N (1987) Acute renal failure in pregnancy. Am J Kidney Dis 9(4):359–62CrossRef Grunfeld JP, Pertuiset N (1987) Acute renal failure in pregnancy. Am J Kidney Dis 9(4):359–62CrossRef
3.
go back to reference Fakhouri F (2016) Pregnancy-related thrombotic microangiopathies: clues from complement biology. Transfus Apher Sci 54(2):199–202CrossRef Fakhouri F (2016) Pregnancy-related thrombotic microangiopathies: clues from complement biology. Transfus Apher Sci 54(2):199–202CrossRef
4.
go back to reference Jungers P, Chauveau D (1997) Pregnancy in renal disease. Kidney Int 52(4):871–885CrossRef Jungers P, Chauveau D (1997) Pregnancy in renal disease. Kidney Int 52(4):871–885CrossRef
5.
go back to reference Piccoli GB, Cabiddu G, Attini R et al (2015) Risk of adverse pregnancy outcomes in women with CKD. J Am Soc Nephrol 26(8):2011–2022CrossRef Piccoli GB, Cabiddu G, Attini R et al (2015) Risk of adverse pregnancy outcomes in women with CKD. J Am Soc Nephrol 26(8):2011–2022CrossRef
6.
go back to reference Mehrabadi A, Liu S, Bartholomew S et al (2014) Hypertensive disorders of pregnancy and the recent increase in obstetric acute renal failure in Canada: population based retrospective cohort study. BMJ 349:g4731CrossRef Mehrabadi A, Liu S, Bartholomew S et al (2014) Hypertensive disorders of pregnancy and the recent increase in obstetric acute renal failure in Canada: population based retrospective cohort study. BMJ 349:g4731CrossRef
7.
go back to reference Callaghan WM, Creanga AA, Kuklina EV (2012) Severe maternal morbidity among delivery and postpartum hospitalizations in the United States. Obstet Gynecol 120(5):1029–1036CrossRef Callaghan WM, Creanga AA, Kuklina EV (2012) Severe maternal morbidity among delivery and postpartum hospitalizations in the United States. Obstet Gynecol 120(5):1029–1036CrossRef
8.
go back to reference Hildebrand AM, Liu K, Shariff SZ et al (2015) Characteristics and outcomes of AKI treated with dialysis during pregnancy and the postpartum period. J Am Soc Nephrol 26(12):3085–3091CrossRef Hildebrand AM, Liu K, Shariff SZ et al (2015) Characteristics and outcomes of AKI treated with dialysis during pregnancy and the postpartum period. J Am Soc Nephrol 26(12):3085–3091CrossRef
9.
go back to reference Frimat M, Decambron M, Lebas C et al (2016) Renal cortical necrosis in postpartum hemorrhage: a case series. Am J Kidney Dis 68(1):50 – 7CrossRef Frimat M, Decambron M, Lebas C et al (2016) Renal cortical necrosis in postpartum hemorrhage: a case series. Am J Kidney Dis 68(1):50 – 7CrossRef
10.
go back to reference Karumanchi SA, Granger JP (2016) Preeclampsia and pregnancy-related hypertensive disorders. Hypertension 67(2):238–242CrossRef Karumanchi SA, Granger JP (2016) Preeclampsia and pregnancy-related hypertensive disorders. Hypertension 67(2):238–242CrossRef
11.
go back to reference Joseph KS, Lisonkova S, Muraca GM et al (2017) Factors underlying the temporal increase in maternal mortality in the United States. Obstet Gynecol 129(1):91–100CrossRef Joseph KS, Lisonkova S, Muraca GM et al (2017) Factors underlying the temporal increase in maternal mortality in the United States. Obstet Gynecol 129(1):91–100CrossRef
12.
go back to reference Knight M, Callaghan WM, Berg C et al (2009) Trends in postpartum hemorrhage in high resource countries: a review and recommendations from the International Postpartum Hemorrhage Collaborative Group. BMC Pregnancy Childbirth 9:55CrossRef Knight M, Callaghan WM, Berg C et al (2009) Trends in postpartum hemorrhage in high resource countries: a review and recommendations from the International Postpartum Hemorrhage Collaborative Group. BMC Pregnancy Childbirth 9:55CrossRef
13.
go back to reference Bateman BT, Berman MF, Riley LE, Leffert LR (2010) The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries. Anesth Analg 110(5):1368–1373CrossRef Bateman BT, Berman MF, Riley LE, Leffert LR (2010) The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries. Anesth Analg 110(5):1368–1373CrossRef
14.
go back to reference Piccoli GB, Cabiddu G, Attini R et al. (2017) Outcomes of pregnancies after kidney transplantation: lessons learned from CKD. A comparison of transplanted, nontransplanted chronic kidney disease patients and low-risk pregnancies: a multicenter nationwide analysis. Transplantation 101(10):2536–2544CrossRef Piccoli GB, Cabiddu G, Attini R et al. (2017) Outcomes of pregnancies after kidney transplantation: lessons learned from CKD. A comparison of transplanted, nontransplanted chronic kidney disease patients and low-risk pregnancies: a multicenter nationwide analysis. Transplantation 101(10):2536–2544CrossRef
15.
go back to reference Piccoli GB, Attini R, Vasario E et al (2013) Pregnancy and chronic kidney disease: a challenge in all CKD stages. Clin J Am Soc Nephrol 5(5):844–855CrossRef Piccoli GB, Attini R, Vasario E et al (2013) Pregnancy and chronic kidney disease: a challenge in all CKD stages. Clin J Am Soc Nephrol 5(5):844–855CrossRef
16.
go back to reference Fakhouri F, Hourmant M, Campistol JM et al (2016) Terminal complement inhibitor eculizumab in adult patients with atypical hemolytic uremic syndrome: a single-arm, open-label trial. Am J Kidney Dis 68(1):84–93CrossRef Fakhouri F, Hourmant M, Campistol JM et al (2016) Terminal complement inhibitor eculizumab in adult patients with atypical hemolytic uremic syndrome: a single-arm, open-label trial. Am J Kidney Dis 68(1):84–93CrossRef
Metadata
Title
Pregnancy-related acute kidney injury in high income countries: still a critical issue
Authors
Fadi Fakhouri
Clément Deltombe
Publication date
01-12-2017
Publisher
Springer International Publishing
Published in
Journal of Nephrology / Issue 6/2017
Print ISSN: 1121-8428
Electronic ISSN: 1724-6059
DOI
https://doi.org/10.1007/s40620-017-0440-8

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