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Social Psychiatry and Psychiatric Epidemiology

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01-04-2011 | Original Paper

Predictors of early adulthood quality of life in children with obsessive–compulsive disorder

Authors: Sean D. Palermo, Michael H. Bloch, Brittany Craiglow, Angeli Landeros-Weisenberger, Philip A. Dombrowski, Kaitlyn Panza, Megan E. Smith, Bradley S. Peterson, James F. Leckman

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 4/2011

Abstract

Objectives

The goal of this study was to determine childhood clinical predictors of quality of life (QoL) in early adulthood in children with obsessive–compulsive disorder (OCD).

Methods

A longitudinal cohort study was conducted with 36 (out of 62 eligible) children with OCD, interviewed once at childhood baseline (mean age 12.1 ± 2.1, range 8.0–15.8), and again in early adulthood after an average follow-up interval of 9 years. QoL was measured in adulthood with the longitudinal interval follow-up evaluation range of impaired functioning tool (LIFE-RIFT).

Results

Forty-two percent of children experienced a remission of OCD symptoms by early adulthood. OCD appeared to most strongly impair the interpersonal relationships and work domains of QoL. QoL and severity of OCD and anxiety symptoms were significantly associated in early adulthood. Primary hoarding symptoms in childhood predicted poor QoL in adulthood. Increased symptoms in the forbidden thoughts dimension in both childhood and adulthood were associated with improved adulthood QoL.

Conclusions

Children for whom OCD symptoms remitted by adulthood showed no evidence of residual impairment in QoL, whereas children whose OCD symptoms failed to remit by adulthood showed at most mild impairment in QoL. Hoarding symptoms in childhood appear to portend not only the persistence of OCD symptoms but also poorer QoL in early adulthood.

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Title: Predictors of early adulthood quality of life in children with obsessive–compulsive disorder
Authors: Sean D. Palermo
Michael H. Bloch
Brittany Craiglow
Angeli Landeros-Weisenberger
Philip A. Dombrowski
Kaitlyn Panza
Megan E. Smith
Bradley S. Peterson
James F. Leckman
Publication date: 01-04-2011
Publisher: Springer-Verlag
Published in: Social Psychiatry and Psychiatric Epidemiology / Issue 4/2011
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI: https://doi.org/10.1007/s00127-010-0194-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Predictors of early adulthood quality of life in children with obsessive–compulsive disorder

Abstract

Objectives

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

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