Published in:
01-12-2020 | Hepatobiliary Tumors
Predicting Survival in Colorectal Liver Metastasis: Time for New Approaches
Authors:
Georgios Antonios Margonis, MD, PhD, Nikolaos Andreatos, MD, Murray F. Brennan, MD
Published in:
Annals of Surgical Oncology
|
Issue 13/2020
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Excerpt
Prognostic models are important tools in forecasting survival outcomes. Prognostication facilitates patient–physician discussions and serves as a critical first step in identifying patient subgroups and potentially individuals with a markedly distinct prognosis. Although such prognostic stratification cannot directly predict treatment benefit, it can help to inform clinical decision-making. In trial design, by directing interventions toward appropriate high-risk groups, prognostic indicators can maximize the likelihood of a clinically meaningful trial. Accurate indices often can allow inclusion of patients most likely to benefit and help to reduce trial cohort size. …
