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Published in: European Journal of Applied Physiology 9/2019

01-09-2019 | Prediabetes | Original Article

Gender-dependent evaluation of football as medicine for prediabetes

Authors: Magni Mohr, May-Britt Skoradal, Thomas Rostgaard Andersen, Peter Krustrup

Published in: European Journal of Applied Physiology | Issue 9/2019

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Abstract

Purpose

Training intensity and health effects of football were investigated gender specifically in individuals with prediabetes.

Methods

Participants with prediabetes (age 60 ± 6 years) were randomised into a football and dietary advice group (FD-men n = 13 and FD-women n = 14) or a dietary advice only group (D-men n = 12 and D-women n = 11). FD performed football training (twice/week for 16 weeks), while both groups received dietary advice. Body composition, bone variables, blood pressure, blood lipid profile and peak oxygen uptake (VO2peak) were determined pre- and post-intervention.

Results

Mean heart rate during football training was 79 ± 2 and 80 ± 3% HRmax for FD-men and FD-women, respectively, with peak heart rate values of 96 ± 1 and 97 ± 2% HRmax, with no gender differences. VO2peak increased more (P < 0.05) in FD-men and FD-women than in D-men and D-women. However, relative delta change in VO2peak was 21 ± 14% in FD-women, which was greater (P < 0.05) than in FD-men (11 ± 12%). Reduction in SBP and DBP, respectively, was similar in FD-men (− 10.8 ± 13.0 and − 7.3 ± 11.8 mmHg) and FD-women (− 11.3 ± 11.0 and − 7.1 ± 6.2 mmHg), with within-gender differences for men. Total plasma cholesterol and LDL cholesterol decreased (P < 0.05) by − 0.7 ± 1.1 and − 0.5 ± 0.9 mmol L−1, respectively, in FD-women and − 0.2 ± 0.4 and − 0.2 ± 0.3 mmol L−1 in FD-men, with no significant gender differences (P = 0.08). Body fat content was lowered (P < 0.05) by 3 and 4%-points in FD-men and FD-women, respectively.

Conclusion

Gender-mixed football training combined with dietary advice causes broad-spectrum health effects for men and women with prediabetes, with minor gender-specific differences. Thus, the intensity and training-induced effects of football training are also high for elderly women with prediabetes.
Literature
go back to reference American Diabetes Association (2017) Lifestyle management Sec. 4. In standards of medical care in diabetesd 2017. Diabetes Care 40(Suppl 1):S33–S43CrossRef American Diabetes Association (2017) Lifestyle management Sec. 4. In standards of medical care in diabetesd 2017. Diabetes Care 40(Suppl 1):S33–S43CrossRef
go back to reference Andersen TR, Schmidt JF, Thomassen M, Hornstrup T, Frandsen U, Randers MB, Hansen PR, Krustrup P, Bangsbo J (2014) A preliminary study: effects of football training on glucose control, body composition, and performance in men with type 2 diabetes. Scand J Med Sci Sports 24(S1):43–56CrossRefPubMed Andersen TR, Schmidt JF, Thomassen M, Hornstrup T, Frandsen U, Randers MB, Hansen PR, Krustrup P, Bangsbo J (2014) A preliminary study: effects of football training on glucose control, body composition, and performance in men with type 2 diabetes. Scand J Med Sci Sports 24(S1):43–56CrossRefPubMed
go back to reference de Sousa MV, Fukui R, Krustrup P, Pereira RM, Silva PR, Rodrigues AC, de Andrade JL, Hernandez AJ, da Silva ME (2014) Positive effects of football on fitness, lipid profile, and insulin resistance in Brazilian patients with type 2 diabetes. Scand J Med Sci Sports 24(S1):57–65CrossRefPubMed de Sousa MV, Fukui R, Krustrup P, Pereira RM, Silva PR, Rodrigues AC, de Andrade JL, Hernandez AJ, da Silva ME (2014) Positive effects of football on fitness, lipid profile, and insulin resistance in Brazilian patients with type 2 diabetes. Scand J Med Sci Sports 24(S1):57–65CrossRefPubMed
go back to reference Devries MC, Hamadeh MJ, Phillips SM, Tarnopolsky MA (2006) Menstrual cycle phase and sex influence muscle glycogen utilization and glucose turnover during moderate-intensity endurance exercise. Am J Physiol Regul Integr Comp Physiol 291(4):1120–1128CrossRef Devries MC, Hamadeh MJ, Phillips SM, Tarnopolsky MA (2006) Menstrual cycle phase and sex influence muscle glycogen utilization and glucose turnover during moderate-intensity endurance exercise. Am J Physiol Regul Integr Comp Physiol 291(4):1120–1128CrossRef
go back to reference Donahue KE, Mielenz TJ, Sloane PD, Callahan LF, Devellis RF (2006) Identifying supports and barriers to physical activity in patients at risk for diabetes. Prev Chronic Dis 3:A119PubMedPubMedCentral Donahue KE, Mielenz TJ, Sloane PD, Callahan LF, Devellis RF (2006) Identifying supports and barriers to physical activity in patients at risk for diabetes. Prev Chronic Dis 3:A119PubMedPubMedCentral
go back to reference Durrer C, Robinson E, Wan Z, Martinez N, Hummel ML, Jenkins NT, Kilpatrick MW, Little JP (2015) Differential impact of acute high-intensity exercise on circulating endothelial microparticles and insulin resistance between overweight/obese males and females. PLoS ONE 24:10 Durrer C, Robinson E, Wan Z, Martinez N, Hummel ML, Jenkins NT, Kilpatrick MW, Little JP (2015) Differential impact of acute high-intensity exercise on circulating endothelial microparticles and insulin resistance between overweight/obese males and females. PLoS ONE 24:10
go back to reference Elbe AM, Strahler K, Krustrup P, Wikman J, Stelter R (2010) Experiencing flow in different types of physical activity intervention programs: three randomized studies. Scand J Med Sci Sports 20(Suppl 1):111–117CrossRefPubMed Elbe AM, Strahler K, Krustrup P, Wikman J, Stelter R (2010) Experiencing flow in different types of physical activity intervention programs: three randomized studies. Scand J Med Sci Sports 20(Suppl 1):111–117CrossRefPubMed
go back to reference Esbjörnsson-Liljedahl M, Sundberg CJ, Norman B, Jansson E (1999) Metabolic response in type I and type II muscle fibers during a 30-s cycle sprint in men and women. J Appl Physiol (1985) 87(4):1326–1332CrossRef Esbjörnsson-Liljedahl M, Sundberg CJ, Norman B, Jansson E (1999) Metabolic response in type I and type II muscle fibers during a 30-s cycle sprint in men and women. J Appl Physiol (1985) 87(4):1326–1332CrossRef
go back to reference Helge EW, Aagaard P, Jakobsen MD, Sundstrup E, Randers MB, Karlsson MK, Krustrup P (2010) Recreational football training decreases risk factors for bone fractures in untrained premenopausal women. Scand J Med Sci Sports 1:31–39CrossRef Helge EW, Aagaard P, Jakobsen MD, Sundstrup E, Randers MB, Karlsson MK, Krustrup P (2010) Recreational football training decreases risk factors for bone fractures in untrained premenopausal women. Scand J Med Sci Sports 1:31–39CrossRef
go back to reference Kharal PM, Prasad PN, Acharya RP (2013) Gross correlation between waist hip ratio and blood sugar level in a village. JNMA J Nepal Med Assoc 52(190):361–364PubMed Kharal PM, Prasad PN, Acharya RP (2013) Gross correlation between waist hip ratio and blood sugar level in a village. JNMA J Nepal Med Assoc 52(190):361–364PubMed
go back to reference Krustrup P, Randers MB, Andersen LJ, Jackman SR, Bangsbo J, Hansen PR (2013) Soccer improves fitness and attenuates cardiovascular risk factors in hypertensive men. Med Sci Sports Exerc 45(3):553–560CrossRefPubMed Krustrup P, Randers MB, Andersen LJ, Jackman SR, Bangsbo J, Hansen PR (2013) Soccer improves fitness and attenuates cardiovascular risk factors in hypertensive men. Med Sci Sports Exerc 45(3):553–560CrossRefPubMed
go back to reference Lidegaard LP, Schwennesen N, Willaing I, Faerch K (2016) Barriers to and motivators for physical activity among people with Type 2 diabetes: patients' perspectives. Diabet Med 33(12):1677–1685CrossRefPubMed Lidegaard LP, Schwennesen N, Willaing I, Faerch K (2016) Barriers to and motivators for physical activity among people with Type 2 diabetes: patients' perspectives. Diabet Med 33(12):1677–1685CrossRefPubMed
go back to reference McQueen MJ, Hawken S, Wang X, Ounpuu S, Sniderman A, Probstfield J, Steyn K, Sanderson JE, Hasani M, Volkova E, Kazmi K, Yusuf S (2008) INTERHEART study investigators. Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study. Lancet 372(9634):224–233. https://doi.org/10.1016/S0140-6736(08)61076-4 CrossRef McQueen MJ, Hawken S, Wang X, Ounpuu S, Sniderman A, Probstfield J, Steyn K, Sanderson JE, Hasani M, Volkova E, Kazmi K, Yusuf S (2008) INTERHEART study investigators. Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study. Lancet 372(9634):224–233. https://​doi.​org/​10.​1016/​S0140-6736(08)61076-4 CrossRef
go back to reference Ottesen L, Jeppesen RS, Krustrup BR (2010) The development of social capital through football and running: studying an intervention program for inactive women. Scand J Med Sci Sports 20(Suppl 1):118–131CrossRefPubMed Ottesen L, Jeppesen RS, Krustrup BR (2010) The development of social capital through football and running: studying an intervention program for inactive women. Scand J Med Sci Sports 20(Suppl 1):118–131CrossRefPubMed
go back to reference Phillips SM, Atkinson SA, Tarnopolsky MA, MacDougall JD (1993) Gender differences in leucine kinetics and nitrogen balance in endurance athletes. J Appl Physiol (1985) 75(5):2134–2141CrossRef Phillips SM, Atkinson SA, Tarnopolsky MA, MacDougall JD (1993) Gender differences in leucine kinetics and nitrogen balance in endurance athletes. J Appl Physiol (1985) 75(5):2134–2141CrossRef
go back to reference Randers MB, Nielsen JJ, Krustrup BR, Sundstrup E, Jakobsen MD, Nybo L, Dvorak J, Bangsbo J, Krustrup P (2010) Positive performance and health effects of a football training program over 12 weeks can be maintained over a 1-year period with reduced training frequency. Scand J Med Sci Sports 20:80–89CrossRefPubMed Randers MB, Nielsen JJ, Krustrup BR, Sundstrup E, Jakobsen MD, Nybo L, Dvorak J, Bangsbo J, Krustrup P (2010) Positive performance and health effects of a football training program over 12 weeks can be maintained over a 1-year period with reduced training frequency. Scand J Med Sci Sports 20:80–89CrossRefPubMed
go back to reference Randers MB, Andersen JL, Petersen J, Sundstrup E, Jakobsen MD, Bangsbo J, Saltin B, Krustrup P (2014) Exercise performance and cardiovascular health variables in 70-year-old male soccer players compared to endurance-trained, strength-trained and untrained age-matched men. J Sports Sci 32:1300–1308CrossRefPubMed Randers MB, Andersen JL, Petersen J, Sundstrup E, Jakobsen MD, Bangsbo J, Saltin B, Krustrup P (2014) Exercise performance and cardiovascular health variables in 70-year-old male soccer players compared to endurance-trained, strength-trained and untrained age-matched men. J Sports Sci 32:1300–1308CrossRefPubMed
go back to reference Sanal E, Ardic F, Kirac S (2013) Effects of aerobic or combined aerobic resistance exercise on body composition in overweight and obese adults: gender differences. A randomized intervention study. Eur J Phys Rehabil Med 49(1):1–11PubMed Sanal E, Ardic F, Kirac S (2013) Effects of aerobic or combined aerobic resistance exercise on body composition in overweight and obese adults: gender differences. A randomized intervention study. Eur J Phys Rehabil Med 49(1):1–11PubMed
go back to reference Scalzo RL, Peltonen GL, Binns SE, Shankaran M, Giordano GR, Hartley DA, Klochak AL, Lonac MC, Paris HL, Szallar SE, Wood LM, Peelor FF, Holmes WE, Hellerstein MK, Bell C, Hamilton KL, Miller BF (2014) Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training. FASEB J 28(6):2705–2714. https://doi.org/10.1096/fj.13-246595 CrossRefPubMed Scalzo RL, Peltonen GL, Binns SE, Shankaran M, Giordano GR, Hartley DA, Klochak AL, Lonac MC, Paris HL, Szallar SE, Wood LM, Peelor FF, Holmes WE, Hellerstein MK, Bell C, Hamilton KL, Miller BF (2014) Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training. FASEB J 28(6):2705–2714. https://​doi.​org/​10.​1096/​fj.​13-246595 CrossRefPubMed
go back to reference Schmidt JF, Andersen LJ, Uth J, Hornstrup T, Christensen J, Midtgaard J, Brasso K, Krustrup P, Rørth M, Hansen PR (2017) Cardiac structure and function in men with prostate cancer receiving androgen-deprivation therapy and the effects of recreational small-sided football training: a randomized controlled trial. World J Cardiovasc Diseases 7:308–322CrossRef Schmidt JF, Andersen LJ, Uth J, Hornstrup T, Christensen J, Midtgaard J, Brasso K, Krustrup P, Rørth M, Hansen PR (2017) Cardiac structure and function in men with prostate cancer receiving androgen-deprivation therapy and the effects of recreational small-sided football training: a randomized controlled trial. World J Cardiovasc Diseases 7:308–322CrossRef
go back to reference Tarnopolsky LJ, MacDougall JD, Atkinson SA, Tarnopolsky MA, Sutton JR (1990) Gender differences in substrate for endurance exercise. J Appl Physiol (1985) 68(1):302–308CrossRef Tarnopolsky LJ, MacDougall JD, Atkinson SA, Tarnopolsky MA, Sutton JR (1990) Gender differences in substrate for endurance exercise. J Appl Physiol (1985) 68(1):302–308CrossRef
go back to reference Uth J, Schmidt JF, Christensen JF, Hornstrup T, Andersen LJ, Hansen PR, Christensen KB, Andersen LL, Helge EW, Brasso K, Rørth M, Krustrup P, Midtgaard J (2013) Effects of recreational soccer in men with prostate cancer undergoing androgen deprivation therapy: study protocol for the 'FC Prostate' randomized controlled trial. BMC Cancer 13:595. https://doi.org/10.1186/1471-2407-13-595 CrossRefPubMedPubMedCentral Uth J, Schmidt JF, Christensen JF, Hornstrup T, Andersen LJ, Hansen PR, Christensen KB, Andersen LL, Helge EW, Brasso K, Rørth M, Krustrup P, Midtgaard J (2013) Effects of recreational soccer in men with prostate cancer undergoing androgen deprivation therapy: study protocol for the 'FC Prostate' randomized controlled trial. BMC Cancer 13:595. https://​doi.​org/​10.​1186/​1471-2407-13-595 CrossRefPubMedPubMedCentral
go back to reference Uth J, Hornstrup T, Schmidt JF, Christensen JF, Frandsen C, Christensen KB, Helge EW, Brasso K, Rørth M, Midtgaard J, Krustrup P (2014) Football training improves lean body mass in men with prostate cancer undergoing androgen deprivation therapy. Scand J Med Sci Sports 24(S1):105–112CrossRefPubMed Uth J, Hornstrup T, Schmidt JF, Christensen JF, Frandsen C, Christensen KB, Helge EW, Brasso K, Rørth M, Midtgaard J, Krustrup P (2014) Football training improves lean body mass in men with prostate cancer undergoing androgen deprivation therapy. Scand J Med Sci Sports 24(S1):105–112CrossRefPubMed
go back to reference Uth J, Hornstrup T, Christensen JF, Christensen KB, Jørgensen NR, Helge EW, Schmidt JF, Brasso K, Helge JW, Jakobsen MD, Andersen LL, Rørth M, Midtgaard J, Krustrup P (2016a) Football training in men with prostate cancer undergoing androgen deprivation therapy: activity profile and short-term skeletal and postural balance adaptations. Eur J Appl Physiol 116(3):471–480. https://doi.org/10.1007/s00421-015-3301-y CrossRefPubMed Uth J, Hornstrup T, Christensen JF, Christensen KB, Jørgensen NR, Helge EW, Schmidt JF, Brasso K, Helge JW, Jakobsen MD, Andersen LL, Rørth M, Midtgaard J, Krustrup P (2016a) Football training in men with prostate cancer undergoing androgen deprivation therapy: activity profile and short-term skeletal and postural balance adaptations. Eur J Appl Physiol 116(3):471–480. https://​doi.​org/​10.​1007/​s00421-015-3301-y CrossRefPubMed
go back to reference Uth J, Hornstrup T, Christensen JF, Christensen KB, Jørgensen NR, Schmidt JF, Brasso K, Jakobsen MD, Sundstrup E, Andersen LL, Rørth M, Midtgaard J, Krustrup P, Helge EW (2016b) Efficacy of recreational football on bone health, body composition, and physical functioning in men with prostate cancer undergoing androgen deprivation therapy: 32-week follow-up of the FC prostate randomised controlled trial. Osteoporos Int 27(4):1507–1518. https://doi.org/10.1007/s00198-015-3399-0 CrossRefPubMed Uth J, Hornstrup T, Christensen JF, Christensen KB, Jørgensen NR, Schmidt JF, Brasso K, Jakobsen MD, Sundstrup E, Andersen LL, Rørth M, Midtgaard J, Krustrup P, Helge EW (2016b) Efficacy of recreational football on bone health, body composition, and physical functioning in men with prostate cancer undergoing androgen deprivation therapy: 32-week follow-up of the FC prostate randomised controlled trial. Osteoporos Int 27(4):1507–1518. https://​doi.​org/​10.​1007/​s00198-015-3399-0 CrossRefPubMed
go back to reference Uth J, Fristrup B, Haahr RD, Brasso K, Helge JW, Rørth M, Midtgaard J, Helge EW, Krustrup P (2018) Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer. Scand J Med Sci Sports 28(S1):61–73CrossRefPubMed Uth J, Fristrup B, Haahr RD, Brasso K, Helge JW, Rørth M, Midtgaard J, Helge EW, Krustrup P (2018) Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer. Scand J Med Sci Sports 28(S1):61–73CrossRefPubMed
go back to reference Wheeler ML, Dunbar SA, Jaacks LM, Karmally W, Mayer-Davis EJ, Wylie-Rosett J, Yancy WS (2012) Macronutrients, food groups, and eating patterns in the management of diabetes: a systematic review of the literature, 2010. Diabetes Care 35:434–445CrossRefPubMedPubMedCentral Wheeler ML, Dunbar SA, Jaacks LM, Karmally W, Mayer-Davis EJ, Wylie-Rosett J, Yancy WS (2012) Macronutrients, food groups, and eating patterns in the management of diabetes: a systematic review of the literature, 2010. Diabetes Care 35:434–445CrossRefPubMedPubMedCentral
go back to reference Williams NH, Hendry M, France B, Lewis R, Wilkinson C (2007) Effectiveness of exercise-referral schemes to promote physical activity in adults: systematic review. Br J Gen Pract 57:979–986CrossRefPubMedPubMedCentral Williams NH, Hendry M, France B, Lewis R, Wilkinson C (2007) Effectiveness of exercise-referral schemes to promote physical activity in adults: systematic review. Br J Gen Pract 57:979–986CrossRefPubMedPubMedCentral
Metadata
Title
Gender-dependent evaluation of football as medicine for prediabetes
Authors
Magni Mohr
May-Britt Skoradal
Thomas Rostgaard Andersen
Peter Krustrup
Publication date
01-09-2019
Publisher
Springer Berlin Heidelberg
Keyword
Prediabetes
Published in
European Journal of Applied Physiology / Issue 9/2019
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI
https://doi.org/10.1007/s00421-019-04188-5

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