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AIDS and Behavior
Published in: AIDS and Behavior 1/2011

Open Access 01-04-2011 | Original Paper

Pre-Exposure Prophylaxis and the Promise of Combination Prevention Approaches

Authors: Susan P. Buchbinder, Albert Liu

Published in: AIDS and Behavior | Special Issue 1/2011

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Abstract

Pre-exposure prophylaxis (PrEP) for HIV prevention is a promising experimental approach currently being tested globally. A number of PrEP trials are evaluating the safety and effectiveness of PrEP in men who have sex with men (MSM) and other populations at risk for HIV, and results will be available from this first generation of efficacy trials over the next few years. Here we review the rationale for orally-administered antiretrovirals for prevention, and outline issues the first generation trials will address as well as questions that may be addressed in future studies. We also describe the rationale for combination prevention approaches that may combine PrEP with other prevention modalities as part of a larger prevention package.
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Metadata
Title
Pre-Exposure Prophylaxis and the Promise of Combination Prevention Approaches
Authors
Susan P. Buchbinder
Albert Liu
Publication date
01-04-2011
Publisher
Springer US
Published in
AIDS and Behavior / Issue Special Issue 1/2011
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-011-9894-1

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