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BMC Public Health
Published in: BMC Public Health 1/2020

Open Access 01-12-2020 | Pre-Eclampsia | Research article

Association of Ambient air Pollution with risk of preeclampsia during pregnancy: a retrospective cohort study

Authors: Lu Jia, Qing Liu, Huiqing Hou, Guangli Guo, Ting Zhang, Songli Fan, Li Wang

Published in: BMC Public Health | Issue 1/2020

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Abstract

Background

Ambient air pollution is becoming a serious environmental problem in China. The results were inconsistent on that air pollution was a risk factor of preeclampsia in pregnancy.

Methods

Total 116,042 pregnant women were enrolled from 22 hospitals in 10 cities of Hebei Province, China from January 1, 2015 to December 31, 2017. The parturients were divided into preeclampsia group (PE group) and non-preeclampsia group (non-PE group). The data of air pollutants, namely, particulate matter (PM)2.5, PM10, NO2, SO2, CO, O3 were collected from China Environmental Inspection Station.

Results

Among the 116,042 pregnant women, 2988 (2.57%) pregnant women were diagnosed with preeclampsia. The concentrations of exposed PM2.5, PM10, NO2 and O3 in the PE group were significantly higher than those in the non-PE group, and they were risk factors of the PE group in the first and second trimester of pregnancy respectively. The concentrations of exposed SO2 and CO in PE patients and non-PE women were not different, but high concentration of these air pollutants were risk factors to PE in the second trimester.

Conclusion

The exposure to PM2.5, PM10, NO2, O3 were risk factors for preeclampsia in the first and second trimester of pregnancy, while only at high level, SO2 and CO were risk factors for preeclampsia in the second trimester of pregnancy.
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Metadata
Title
Association of Ambient air Pollution with risk of preeclampsia during pregnancy: a retrospective cohort study
Authors
Lu Jia
Qing Liu
Huiqing Hou
Guangli Guo
Ting Zhang
Songli Fan
Li Wang
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2020
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-020-09719-w

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