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Published in: Advances in Therapy 8/2017

Open Access 01-08-2017 | Review

Practical Considerations for the Use of Subcutaneous Treatment in the Management of Dyslipidaemia

Authors: Franck Boccara, Ricardo Dent, Luis Ruilope, Paul Valensi

Published in: Advances in Therapy | Issue 8/2017

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Abstract

Suboptimal drug adherence represents a major challenge to effective primary and secondary prevention of cardiovascular disease. While adherence is influenced by multiple considerations, polypharmacy and dosing frequency appear to be rate-limiting factors in patient satisfaction and subsequent adherence. The cardiovascular and metabolic therapeutic areas have recently benefited from a number of advances in drug therapy, in particular protease proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and incretin-based therapies, respectively. These drugs are administered subcutaneously and offer efficacious treatment options with reduced dosing frequency. Whilst patients with diabetes and diabetologists are well initiated to injectable therapies, the cardiovascular therapeutic arena has traditionally been dominated by oral agents. It is therefore important to examine the practical aspects of treating patients with these new lipid-lowering agents, to ensure they are optimally deployed in everyday clinical practice.
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Metadata
Title
Practical Considerations for the Use of Subcutaneous Treatment in the Management of Dyslipidaemia
Authors
Franck Boccara
Ricardo Dent
Luis Ruilope
Paul Valensi
Publication date
01-08-2017
Publisher
Springer Healthcare
Published in
Advances in Therapy / Issue 8/2017
Print ISSN: 0741-238X
Electronic ISSN: 1865-8652
DOI
https://doi.org/10.1007/s12325-017-0586-8

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