Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2014

Open Access 01-12-2014 | Case report

Postoperative hemorrhage in an elderly patient with a glioblastoma multiform and a calcified chronic subdural hematoma

Authors: Jun Cai, Yanting Zhang, Xiaoxin Bai, Shaoxue Li, Jinhua Chen, Ruicong Chen, Hao Lin, Shengping Huang

Published in: World Journal of Surgical Oncology | Issue 1/2014

Login to get access

Abstract

Background

Cases with brain tumor and subdural hematoma are rare; surgical management of the elderly patients with a glioblastoma multiform (GBM) and a chronic subdural hematoma (CSDH) can be intractable.

Case description

We report a 77-year-old patient, who had a left front lobe GBM and a giant, calcified, left frontoparietaloccipitotemporal CSDH. The patient recovered well from anesthesia after removal of the GBM and CSDH. However, the patient developed severe hemiplegia and aphasia because of the in-situ hemorrhage 1 day later. Laboratory tests indicated disseminated intravascular coagulation (DIC) leading to the postoperative hemorrhage. The patient was left with hemiparesis and alalia after the in-situ hematoma evacuation.

Conclusions

We presume elderly patients have a higher incidence of postoperative hemorrhage in residual intracranial cavity owing to higher possibility to get DIC. A less aggressive surgical management could be a more appropriate choice.
Appendix
Available only for authorised users
Literature
1.
Roger EP, Butler J, Benzel EC: Neurosurgery in the elderly: brain tumors and subdural hematomas. Clin Geriatr Med. 2006, 22: 623-644. 10.1016/j.cger.2006.04.002.CrossRefPubMed
2.
Anton K, Baehring JM, Mayer T: Glioblastoma multiforme: overview of current treatment and future perspectives. Hematol Oncol Clin North Am. 2012, 26: 825-853. 10.1016/j.hoc.2012.04.006.CrossRefPubMed
3.
Imaizumi S, Onuma T, Kameyama M, Naganuma H: Organized chronic subdural hematoma requiring craniotomy–five case reports. Neurol Med Chir (Tokyo). 2001, 41: 19-24. 10.2176/nmc.41.19.CrossRef
4.
Taylor FB, Toh CH, Hoots WK, Wada H, Levi M: Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost. 2001, 86: 1327-1330.PubMed
5.
Berger MM, Ravussin P, Vielle G, Fankhauser H: Life-threatening hemorrhagic diathesis due to disseminated intravascular coagulation during elective brain tumor surgery. J Neurosurg Anesthesiol. 1995, 7: 26-29. 10.1097/00008506-199501000-00005.CrossRefPubMed
6.
Brecknell JE, McLean CA, Hirano H, Malham GM: Disseminated intravascular coagulation complicating resection of a malignant meningioma. Br J Neurosurg. 2006, 20: 239-241. 10.1080/02688690600852647.CrossRefPubMed
7.
Palmer JD, Francis DA, Roath OS, Francis JL, Iannotti F: Hyperfibrinolysis during intracranial surgery: effect of high dose aprotinin. J Neurol Neurosurg Psychiatry. 1995, 58: 104-106. 10.1136/jnnp.58.1.104.PubMedCentralCrossRefPubMed
8.
Portugal JR, Alencar A, Brito Lira LC, Carvalho P: Melanotic meningioma complicated by disseminated intravascular coagulation. Surg Neurol. 1984, 21: 275-281. 10.1016/0090-3019(84)90202-7.CrossRefPubMed
9.
Velez AM, Friedman WA: Disseminated intravascular coagulation during resection of a meningioma: case report. Neurosurgery. 2011, 68: E1165-1169. discussion E1169PubMed
10.
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O’Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M: Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010, 17: 98-110. 10.1016/j.ccr.2009.12.020.PubMedCentralCrossRefPubMed
Metadata
Title
Postoperative hemorrhage in an elderly patient with a glioblastoma multiform and a calcified chronic subdural hematoma
Authors
Jun Cai
Yanting Zhang
Xiaoxin Bai
Shaoxue Li
Jinhua Chen
Ruicong Chen
Hao Lin
Shengping Huang
Publication date
01-12-2014
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2014
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-12-110

Other articles of this Issue 1/2014

World Journal of Surgical Oncology 1/2014 Go to the issue

Case report

Multiple primary malignancies of the liver and the colon: a complex diagnostic and decisional process with a final unanswered question

Case report

Perivascular epitheloid cell tumor (PEComa) mimicking retroperitoneal liposarcoma

Research

Expression of stromal cell-derived factor 1 and CXCR7 ligand receptor system in pancreatic adenocarcinoma

Case report

Extra-gastrointestinal stromal tumor of the pancreas: case report and review of the literature

Research

Neogenin expression is inversely associated with breast cancer grade in ex vivo

Case report

Chondrosarcoma of the nasal cavity in a patient with Maffucci syndrome: case report and review of the literature