Skip to main content
Top
Published in: Current Atherosclerosis Reports 7/2023

10-05-2023 | Positron Emission Tomography

The Role of Cardiac PET in Diagnosis and Prognosis of Ischemic Heart Disease: Optimal Modality Across Different Patient Populations

Authors: Malek Nayfeh, Ahmed Ibrahim Ahmed, Jean Michel Saad, Fares Alahdab, Mouaz Al-Mallah

Published in: Current Atherosclerosis Reports | Issue 7/2023

Login to get access

Abstract

Purpose of Review

Despite single-photon emission computerized tomography (SPECT) being the most used nuclear imaging technique for diagnosis of coronary artery disease (CAD), many now consider positron emission tomography (PET) as a superior modality. This review will focus on the advances of cardiac PET in recent years and its advantages compared to SPECT in diagnosis and prognosis of CAD.

Recent Findings

PET’s higher resolution and enhanced diagnostic accuracy, as well as lower radiation exposure, all help explain the rationale for its wider spread and use. PET also allows for measurement of myocardial blood flow (MBF) and myocardial flow reserve (MFR), which aids in several different clinical scenarios, such as diagnosing multivessel disease or identifying non-responders. PET has also been shown to be useful in diagnosing CAD in various specific populations, such as patients with prior COVID-19 infection, cardiac transplant, and other comorbidities.
Literature
12.
go back to reference Tamaki N, Yonekura Y, Senda M, Yamashita K, Koide H, Saji H, et al. Value and limitation of stress thallium-201 single photon emission computed tomography: comparison with nitrogen-13 ammonia positron tomography. J Nucl Med. 1988;29(7):1181–8.PubMed Tamaki N, Yonekura Y, Senda M, Yamashita K, Koide H, Saji H, et al. Value and limitation of stress thallium-201 single photon emission computed tomography: comparison with nitrogen-13 ammonia positron tomography. J Nucl Med. 1988;29(7):1181–8.PubMed
32.
49.
go back to reference Poothullil JM. Diabetes and decline in heart disease mortality. JAMA. 1999;282(12):1132-. doi: 10–1001/pubs.JAMA-ISSN-0098–7484–282–12-jbk0922. Poothullil JM. Diabetes and decline in heart disease mortality. JAMA. 1999;282(12):1132-. doi: 10–1001/pubs.JAMA-ISSN-0098–7484–282–12-jbk0922.
Metadata
Title
The Role of Cardiac PET in Diagnosis and Prognosis of Ischemic Heart Disease: Optimal Modality Across Different Patient Populations
Authors
Malek Nayfeh
Ahmed Ibrahim Ahmed
Jean Michel Saad
Fares Alahdab
Mouaz Al-Mallah
Publication date
10-05-2023
Publisher
Springer US
Published in
Current Atherosclerosis Reports / Issue 7/2023
Print ISSN: 1523-3804
Electronic ISSN: 1534-6242
DOI
https://doi.org/10.1007/s11883-023-01107-0

Other articles of this Issue 7/2023

Current Atherosclerosis Reports 7/2023 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.