Top

Published in:

01-12-2020 | Positron Emission Tomography | Editorial

Auxiliary ischemic markers, the role of left ventricular dyssynchrony

Author: Teresa Massardo, MD

Published in: Journal of Nuclear Cardiology | Issue 6/2020

Excerpt

Myocardial ischemia due to coronary artery disease (CAD) could be detected with a high sensitivity using available imaging methods. However, even with stress single photon emission tomography (SPECT) myocardial perfusion imaging (MPI) ischemia may not be detected in some patients. …

Nakanishi R, Gransar H, Slomka P, Arsanjani R, Shalev A, Otaki Y, et al. Predictors of high-risk coronary artery disease in subjects with normal SPECT myocardial perfusion imaging. J Nucl Cardiol 2016;23:530-41.CrossRef

Boogers MJ, Chen J, van Bommel RJ, Borleffs CJ, Dibbets-Schneider P, van der Hiel B, et al. Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion SPECT. Eur J Nucl Med Mol Imaging 2011;38:230-8.CrossRef

Chen J, Garcia EV, Folks RD, Cooke CD, Faber TL, Tauxe EL, et al. Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: Development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. J Nucl Cardiol 2005;12:687-95.CrossRef

Henneman MM, Chen J, Dibbets-Schneider P, Stokkel MP, Bleeker GB, Ypenburg C, et al. Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT? J Nucl Med 2007;48:1104-11.CrossRef

Nakajima K, Okuda K, Matsuo S, Kiso K, Kinuya S, Garcia EV. Comparison of phase dyssynchrony analysis using gated myocardial perfusion imaging with four software programs: Based on the Japanese Society of Nuclear Medicine Working Group normal database. J Nucl Cardiol 2017;24:611-21.CrossRef

Chen J, Garcia EV, Bax JJ, Iskandrian AE, Borges-Neto S, Soman P. SPECT myocardial perfusion imaging for the assessment of left ventricular mechanical dyssynchrony. J Nucl Cardiol 2011;18:685-94.CrossRef

Trimble MA, Velazquez EJ, Adams GL, Honeycutt EF, Pagnanelli RA, Barnhart HX, et al. Repeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony. Nucl Med Commun 2008;29:374-81.CrossRef

AlJaroudi W, Jaber WA, Cerqueira MD. Effect of tracer dose on left ventricular mechanical dyssynchrony indices by phase analysis of gated single photon emission computed tomography myocardial perfusion imaging. J Nucl Cardiol 2012;19:63-72.CrossRef

Barron AJ, Xavier R, Al-Housni M, Reyes E, Underwood R. Phase analysis, a novel SPECT technique for left ventricular dyssynchrony: Are degrees and milliseconds interchangeable? J Nucl Cardiol 2019. https://doi.org/10.1007/s12350-018-01574-y.CrossRefPubMed

10.

AlJaroudi W, Alraies MC, DiFilippo F, Brunken RC, Cerqueira MD, Jaber WA. Effect of stress testing on left ventricular mechanical synchrony by phase analysis of gated positron emission tomography in patients with normal myocardial perfusion. Eur J Nucl Med Mol Imaging 2012;39:665-72.CrossRef

11.

Chen CC, Shen TY, Chang MC, Hung GU, Chen WC, Kao CH, et al. Stress-induced myocardial ischemia is associated with early post-stress left ventricular mechanical dyssynchrony as assessed by phase analysis of ²⁰¹Tl gated SPECT myocardial perfusion imaging. Eur J Nucl Med Mol Imaging 2012;39:1904-9.CrossRef

12.

Singh H, Patel CD, Sharma P, Naik N, Singh S, Narang R. Does perfusion pattern influence stress-induced changes in left ventricular mechanical dyssynchrony on thallium-201-gated SPECT myocardial perfusion imaging? J Nucl Cardiol 2015;22:36-43.CrossRef

13.

Huang WS, Huang CH, Lee CL, Chen CP, Hung GU, Chen J. Relation of early post-stress left ventricular dyssynchrony and the extent of angiographic coronary artery disease. J Nucl Cardiol 2014;21:1048-56.CrossRef

14.

Hung GU, Chen CP, Yang KT. Incremental value of ischemic stunning on the detection of severe and extensive coronary artery disease in dipyridamole Tl-201 gated myocardial perfusion imaging. Int J Cardiol 2005;105:108-10.CrossRef

15.

Swett E, Massardo T, Hiplan E, Paillahueque G, Prat H. Intraventricular synchronism value for ischemia detection with Dipyridamole Sestamibi myocardial SPECT. In: Alasbimn Journal 2018 (XXVI Congreso ALASBIMN noviembre 2017, Santiago, Chile).

16.

Aljaroudi W, Koneru J, Heo J, Iskandrian AE. Impact of ischemia on left ventricular dyssynchrony by phase analysis of gated single photon emission computed tomography myocardial perfusion imaging. J Nucl Cardiol 2011;18:36-42.CrossRef

17.

Van Kriekinge SD, Nishina H, Ohba M, Berman DS, Germano G. Automatic global and regional phase analysis from gated myocardial perfusion SPECT imaging: Application to the characterization of ventricular contraction in patients with left bundle branch block. J Nucl Med 2008;49:1790-7.CrossRef

18.

Takahashi N, Yamamoto A, Tezuka S, Ishikawa M, Abe J, Amitani K, et al. Assessment of left ventricular dyssynchrony during development of heart failure by a novel program using ECG-gated myocardial perfusion SPECT. Circ J 2008;72:370-7.CrossRef

19.

AlJaroudi W, Jaber WA, Grimm RA, Marwick T, Cerqueira MD. Alternative methods for the assessment of mechanical dyssynchrony using phase analysis of gated single photon emission computed tomography myocardial perfusion imaging. Int J Cardiovasc Imaging 2012;28:1385-94.CrossRef

20.

Cooke CD, Esteves FP, Chen J, Garcia EV. Left ventricular mechanical synchrony from stress and rest ⁸²Rb PET myocardial perfusion ECG-gated studies: differentiating normal from LBBB patients. J Nucl Cardiol 2011;18:1076-85.CrossRef

21.

Peix A, Cabrera LO, Padron K, Rodriguez L, Fernandez J, Lopez G, et al. Association between non-perfusion parameters and presence of ischemia in gated-SPECT myocardial perfusion imaging studies. J Nucl Cardiol 2018;25:609-15.CrossRef

22.

Hida S, Chikamori T, Tanaka H, Igarashi Y, Shiba C, Usui Y, et al. Diagnostic value of left ventricular dyssynchrony after exercise and at rest in the detection of multivessel coronary artery disease on single-photon emission computed tomography. Circ J 2012;76:1942-52.CrossRef

23.

Kerrigan J, Shivapour D, Tuzcu EM, Sabik EM, Jaber WA. Acute left ventricular dys-synchrony during regadenason PET myocardial perfusion stress test. J Nucl Cardiol 2015;22:388-90.CrossRef

24.

Massardo T, Gonzalez P, Humeres P, Chamorro H, Ayala F, Yovanovich J, et al. Simultaneous assessment of function and perfusion during dipyridamole-handgrip Tc-99m sestamibi imaging in chronic coronary artery disease. Ann Nucl Med 1999;13:121-5.CrossRef

25.

Bestetti A, Cuko B, Decarli A, Galli A, Lombardi F. Additional value of systolic wall thickening in myocardial stunning evaluated by stress–rest gated perfusion SPECT. J Nucl Cardiol 2017. https://doi.org/10.1007/s12350-017-1115-5.CrossRefPubMed

26.

Bestetti A, Cuko B, Gasparini M, De Servi S. Better characterization of dipyridamole-induced myocardial stunning by systolic wall thickening. A gated perfusion SPECT study. J Nucl Cardiol 2018. https://doi.org/10.1007/s12350-018-1340-6.CrossRefPubMed

27.

Aggarwal H, AlJaroudi WA, Mehta S, Mannon R, Heo J, Iskandrian AE, et al. The prognostic value of left ventricular mechanical dyssynchrony using gated myocardial perfusion imaging in patients with end-stage renal disease. J Nucl Cardiol 2014;21:739-46.CrossRef

28.

Hess PL, Shaw LK, Fudim M, Iskandrian AE, Borges-Neto S. The prognostic value of mechanical left ventricular dyssynchrony defined by phase analysis from gated single-photon emission computed tomography myocardial perfusion imaging among patients with coronary heart disease. J Nucl Cardiol 2017;24:482-90.CrossRef

29.

Bajaj NS, Singh S, Farag A, El-Hajj S, Heo J, Iskandrian AE, et al. The prognostic value of non-perfusion variables obtained during vasodilator stress myocardial perfusion imaging. J Nucl Cardiol 2016;23:390-413.CrossRef

Title: Auxiliary ischemic markers, the role of left ventricular dyssynchrony
Author: Teresa Massardo, MD
Publication date: 01-12-2020
Publisher: Springer International Publishing
Keyword: Positron Emission Tomography
Published in: Journal of Nuclear Cardiology / Issue 6/2020
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-019-01606-1

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Auxiliary ischemic markers, the role of left ventricular dyssynchrony

Excerpt

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 6/2020

Increased myocardial 18F-FDG uptake as a marker of Doxorubicin-induced oxidative stress

CRAX: A simple cardiovascular risk assessment tool to predict risk of acute myocardial infarction or death

18F-FDG uptake of the right ventricle is an important predictor of histopathologic diagnosis by endomyocardial biopsy in patients with cardiac sarcoidosis

High-frequency QRS analysis to supplement ST evaluation in exercise stress electrocardiography: Incremental diagnostic accuracy and net reclassification

Transient ischemic dilation in hypertrophic cardiomyopathy: A complex sign in a complex disease

Automated dynamic motion correction using normalized gradient fields for 82rubidium PET myocardial blood flow quantification

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page