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01-01-2018 | Population Data

Population genetic analysis of the Globalfiler STR loci in 3032 individuals from the Altay Han population of Xinjiang in northwest China

Authors: XueBo Li, Liangliang Li, Qingshan Wang, Jianzhong Zhang, Wendong Ge, Rufeng Bai, Xiaojun Yu, Meisen Shi

Published in: International Journal of Legal Medicine | Issue 1/2018

Abstract

The genetic polymorphisms of 21 autosomal short tandem repeat (STR) loci included in the GlobalFiler™ PCR Amplification Kit were evaluated in 3032 unrelated individuals Altay Han of Xinjiang, northwest China. All of the loci reached the Hardy-Weinberg equilibrium. These loci were examined to determine allele frequencies and forensic statistical parameters. SE33 showed the greatest power of discrimination in Altay Han population, whereas TPOX showed the lowest. The combined discrimination power and probability of excluding paternity of the 21 autosomal STR loci were 0.999999999999999999999999889838 and 0.999999996664704, respectively. Both pairwise genetic distance and phylogenetic methods indicated that the Altay Han had the closest genetic relationship with the Han origin and Hui populations. The present results revealed that the GlobalFiler system had a high level of polymorphism in Altay Han population and hence could be a powerful tool for forensic application and population genetic study.

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Wang DY, Gopinath S, Lagace RE, Norona W, Hennessy LK, Short ML, Mulero JJ (2015) Developmental validation of the GlobalFiler® Express PCR Amplification Kit: a 6-dye multiplex assay for the direct amplification of reference samples. Forensic Sci Int Genet 19:148–155CrossRef

Hennessy LK, Mehendale N, Chear K, Jovanovich S, Williams S, Park C, Gangano S (2014) Developmental validation of the GlobalFiler® express kit, a 24-marker STR assay, on the RapidHIT® System. Forensic Sci Int Genet 13:247–258CrossRef

Hammond HA, Jin L, Zhong Y, Caskey CT, Chakraborty R (1994) Evaluation of 13 short tandem repeat loci for use in personal identification applications. Am J Hum Genet 55:175–189PubMedPubMedCentral

Butler JM, Hill CR (2012) Biology and genetics of new autosomal STR loci useful for forensic DNA analysis. Forensic Sci Rev 24:15–26PubMed

Hares DR (2015) Selection and implementation of expanded CODIS core loci in the United States. Forensic Sci Int Genet 17:33–34CrossRef

Hares DR (2012) Expanding the CODIS core loci in the United States. Forensic Sci Int Genet 6:e52–e54CrossRef

Walsh PS, Metzger DA, Higuchi R (1991) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. BioTechniques 10:506–513PubMed

Bar W, Brinkmann B, Budowle B, Carracedo A, Gill P, Lincoln P, MayrW OB (1997) DNA recommendations. Further report of the DNA commission of the ISFH regarding the use of short tandem repeat systems. International Society for Forensic Haemogenetics. Int J Legal Med 110:175–176CrossRef

Lincoln PJ (1997) DNA recommendations—further report of the DNA commission of the ISFH regarding the use of short tandem repeat systems. Forensic Sci Int 87:181–184CrossRef

10.

Zhao F, Wu XY, Cai GQ, Xu CC (2003) The application ofmodified-Powerstates software in forensic biostatistics (in Chinese). Chin J Forensic Med 18:297–298

11.

Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10:564–567CrossRef

12.

Weir B, Cockerham CC (1984) Estimating F-statistics for the analysis of population structure. Evolution 38(6):1358–1370PubMed

13.

Weir BS, Hill WG (2002) Estimating F-statistics. Annu Rev Genet 36:721–750CrossRef

14.

Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599CrossRef

15.

Ramos-González B, Aguilar-Velázquez JA, Chávez-Briones MDL, Delgado-Chavarría JR, Alfaro-Lopez E, Rangel-Villalobos H (2016) Population data of 24 STRs in Mexican-Mestizo population from Monterrey, Nuevo Leon (Northeast, Mexico) based on Powerplex® Fusion and GlobalFiler® kits. Forensic Sci Int Genet 21:e15–e17CrossRef

16.

Guerreiro S, Ribeiro T, Porto MJ, Carneiro De Sousa MJ, Dario P (2017) Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal. Int J Legal Med 131:365–368CrossRef

17.

Ng J, Oldt RF, McCulloh KL, Weise JA, Viray J, Budowle B, Smith DG, Kanthaswamy S (2016) Native American population data based on the Globalfiler® autosomal STR loci. Forensic Sci Int Genet 24:e12–e13CrossRef

18.

Carracedo A, Butler JM, Gusmao L, Linacre A, Parson W, Roewer L, Schneider PM (2014) Update of the guidelines for the publication of genetic population data. Forensic Sci Int Genet 10:1–2CrossRef

Title: Population genetic analysis of the Globalfiler STR loci in 3032 individuals from the Altay Han population of Xinjiang in northwest China
Authors: XueBo Li
Liangliang Li
Qingshan Wang
Jianzhong Zhang
Wendong Ge
Rufeng Bai
Xiaojun Yu
Meisen Shi
Publication date: 01-01-2018
Publisher: Springer Berlin Heidelberg
Published in: International Journal of Legal Medicine / Issue 1/2018
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-017-1641-3

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Population genetic analysis of the Globalfiler STR loci in 3032 individuals from the Altay Han population of Xinjiang in northwest China

Abstract

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Abstract

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