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Published in: Virology Journal 1/2020

Open Access 01-12-2020 | Polymerase Chain Reaction | Research

A systematic literature review and meta-analysis of characterization of canine parvoviruses 2 prevalent in mainland China

Authors: Bo Dong, Gaoqiang Zhang, Jiajia Zhang, Junyu Bai, Weiming Lin

Published in: Virology Journal | Issue 1/2020

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Abstract

Background

Canine parvovirus 2 (CPV-2) is a pathogenic virus that infects dogs, causing a highly infectious disease. Monitoring CPV-2 spread is an important part of prevention; however, the prevalence and epidemiological characteristics of CPV-2 have not been systematically evaluated and analyzed in mainland China. Therefore, a systematic review and meta-analysis were performed to assess prevalence and epidemiological characteristics of CPV-2 in domestic dogs in mainland China.

Methods

In this study, Chinese and English literature on CPV-2 epidemiology published between January 2006 and December 2019 was evaluated. Regarding meta-analysis, the random-effect model was employed by forest plot with 95% of confidence interval. The number of CPV-2 infections was identified and the pooled prevalence of infection, as well as the epidemiological characteristics, was calculated using meta-analysis.

Results

A total of 39 studies (data from 137,844 dogs) met the evaluation criteria and were used in our study. The pooled prevalence of CPV-2 infection in mainland China was 36%. CPV-2 infection were associated with age, breed, sampling season and immunization status, but not with gender, publication time and diagnostic methods.

Conclusions

Our results indicated that CPV-2 is prevalent among dogs in China. It is therefore necessary to carry out continuous surveillance and epidemiological studies of CPV-2. In addition, accordingly, effective measures should be taken to prevent the transmission and spread of CPV-2 among the Chinese dog population.
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Metadata
Title
A systematic literature review and meta-analysis of characterization of canine parvoviruses 2 prevalent in mainland China
Authors
Bo Dong
Gaoqiang Zhang
Jiajia Zhang
Junyu Bai
Weiming Lin
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2020
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/s12985-020-01462-3

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