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European Journal of Clinical Microbiology & Infectious Diseases
Published in: European Journal of Clinical Microbiology & Infectious Diseases 12/2007

01-12-2007 | Brief Report

Platelia Aspergillus assay for diagnosis of disseminated histoplasmosis

Authors: S. Ranque, R. Pelletier, A. Michel-Nguyen, F. Dromer

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 12/2007

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Abstract

The Platelia Aspergillus assay tested positive in 8 of 11 patients with disseminated histoplasmosis. While other available methods for diagnosis have several drawbacks, this cross-reactivity is particularly valuable in the perspective of practitioners outside the USA who cannot use the test detecting antigen of Histoplasma capsulatum.
Literature
1.
Genot S, Franck J, Forel J-M, Rebaudet S, Ajzenberg D, Maues de Paula A, Dardé M-L, Stein A, Ranque S (2007) Severe Toxoplasma gondii I/III recombinant genotype encephalitis in a HIV patient. J Clin Microbiol (in press)
2.
Girouard G, Lachance C, Pelletier R (2007) Observations on (1-3)-{beta}-D-glucan detection as a diagnostic tool in endemic mycosis caused by Histoplasma or Blastomyces. J Med Microbiol 56(Pt 7):1001–1002PubMedCrossRef
3.
Dalle F, Charles PE, Blanc K, Caillot D, Chavanet P, Dromer F, Bonnin A (2005) Cryptococcus neoformans Galactoxylomannan contains an epitope(s) that is cross-reactive with Aspergillus Galactomannan. J Clin Microbiol 43(6):2929–2931PubMedCrossRef
4.
Wheat LJ, Hackett E, Durkin M, Connolly P, Petraitiene R, Walsh TJ, Knox K, Hage C (2007) Histoplasmosis-associated cross-reactivity in the BioRad Platelia Aspergillus enzyme immunoassay. Clin Vaccine Immunol 14(5):638–640PubMedCrossRef
5.
Wheat LJ (2006) Histoplasmosis: a review for clinicians from non-endemic areas. Mycoses 49(4):274–282PubMedCrossRef
6.
Wheat LJ (2006) Antigen detection, serology, and molecular diagnosis of invasive mycoses in the immunocompromised host. Transpl Infect Dis 8(3):128–139PubMedCrossRef
Metadata
Title
Platelia Aspergillus assay for diagnosis of disseminated histoplasmosis
Authors
S. Ranque
R. Pelletier
A. Michel-Nguyen
F. Dromer
Publication date
01-12-2007
Publisher
Springer-Verlag
Published in
European Journal of Clinical Microbiology & Infectious Diseases / Issue 12/2007
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-007-0380-7

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