Skip to main content
Top
Published in: Italian Journal of Pediatrics 1/2020

Open Access 01-12-2020 | Plague | Letter to the Editor

A caregiver-reported global severity assessment in pediatric atopic eczema: the Comano score

Authors: Mattia Giovannini, Davide Geat, Gabriele Barlocco, Riccardo Pertile, Francesca Mori, Cesare Filippeschi, Elio Novembre, Mario Cristofolini, Ermanno Baldo

Published in: Italian Journal of Pediatrics | Issue 1/2020

Login to get access

Abstract

Atopic eczema (AE) is the most common inflammatory skin disease in infancy and its prevalence is rising worldwide. It has a wide social impact on the affected children and their families’ lives. AE can have a chronic and heterogeneous course, with periods of remission and relapse of the clinical manifestations. For this reason, its severity assessment through standardized outcome measures becomes a fundamental guide for health professionals, who can manage AE following evidence-based medicine principles in their everyday clinical practice or in clinical trials.
Several scoring systems have been recognized to assess the clinical manifestations of AE, both from the physician’s and the patient’s point of view. Despite the scoring systems standardized for adults, there are very few published options about the expression of a patient/caregiver-centered global severity assessment specifically for pediatric AE. For this reason, the aim of our study was to evaluate a new, quick, user-friendly and feasible caregiver-reported global severity assessment for pediatric AE. Based on a 0–10 numerical rating scale in pediatric AE, we named this scoring system the Comano score.
We carried out a cross-sectional observational study enrolling a total of 867 patients aged from 1 to 16 years (males 49.5%, mean patient’s age 5.9 years, standard deviation ±3.6 years) with a previous doctor-confirmed diagnosis of AE, who underwent balneotherapy at Comano Thermal Center (Comano, Trentino, Italy). A strong correlation between Comano score and SCORing Atopic Dermatitis (SCORAD) was observed (r = 0.74, p < 0.0001).
According to our results, the Comano score may be a promising new tool for the expression of a caregiver-reported global severity assessment in pediatric AE. However, further data are needed to confirm our preliminary findings before health professionals can use this scoring system in their everyday clinical practice to manage pediatric AE. Still, as a patient-focused measure, the Comano score may facilitate delivering person-centered care so as to define a measure for a clinical impact that can be meaningful to the subject, which is gaining importance in modern medicine.
Literature
1.
go back to reference Odhiambo JA, Williams HC, Clayton TO, Robertson CF, Asher MI. Global variations in prevalence of eczema symptoms in children from ISAAC phase three. J Allergy Clin Immunol. 2009;124(6):1251–8.CrossRef Odhiambo JA, Williams HC, Clayton TO, Robertson CF, Asher MI. Global variations in prevalence of eczema symptoms in children from ISAAC phase three. J Allergy Clin Immunol. 2009;124(6):1251–8.CrossRef
2.
go back to reference Zinelli C, Caffarelli C, Strid J, Jaffe A, Atherton DJ. Measurement of nitric oxide and 8-isoprostane in exhaled breath of children with atopic eczema. Clin Exp Dermatol. 2009;34(5):607–12.CrossRef Zinelli C, Caffarelli C, Strid J, Jaffe A, Atherton DJ. Measurement of nitric oxide and 8-isoprostane in exhaled breath of children with atopic eczema. Clin Exp Dermatol. 2009;34(5):607–12.CrossRef
3.
go back to reference Schmitt J, Langan S, Deckert S, Svensson A, von Kobyletzki L, et al. Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation. J Allergy Clin Immunol. 2013;132(6):1337–47.CrossRef Schmitt J, Langan S, Deckert S, Svensson A, von Kobyletzki L, et al. Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation. J Allergy Clin Immunol. 2013;132(6):1337–47.CrossRef
4.
go back to reference Leshem YA, Hajar T, Hanifin JM, Simpson EL. What the eczema area and severity index score tells us about the severity of atopic dermatitis: an interpretability study. Br J Dermatol. 2015;172(5):1353–7.CrossRef Leshem YA, Hajar T, Hanifin JM, Simpson EL. What the eczema area and severity index score tells us about the severity of atopic dermatitis: an interpretability study. Br J Dermatol. 2015;172(5):1353–7.CrossRef
5.
go back to reference Kunz B, Oranje AP, Labrèze L, Stalder JF, Ring J, et al. Clinical validation and guidelines for the SCORAD index: consensus report of the European task force on atopic dermatitis. Dermatology. 1997;195(1):10–9.CrossRef Kunz B, Oranje AP, Labrèze L, Stalder JF, Ring J, et al. Clinical validation and guidelines for the SCORAD index: consensus report of the European task force on atopic dermatitis. Dermatology. 1997;195(1):10–9.CrossRef
7.
go back to reference Stalder JF, Barbarot S, Wollenberg A, Holm EA, De Raeve L, et al. Patient-oriented SCORAD (PO-SCORAD): a new self-assessment scale in atopic dermatitis validated in Europe. Allergy. 2011;66(8):1114–21.CrossRef Stalder JF, Barbarot S, Wollenberg A, Holm EA, De Raeve L, et al. Patient-oriented SCORAD (PO-SCORAD): a new self-assessment scale in atopic dermatitis validated in Europe. Allergy. 2011;66(8):1114–21.CrossRef
8.
go back to reference Charman CR, Venn AJ, Ravenscroft JC, Williams HC. Translating patient-oriented eczema measure (POEM) scores into clinical practice by suggesting severity strata derived using anchor-based methods. Br J Dermatol. 2013;169(6):1326–32.CrossRef Charman CR, Venn AJ, Ravenscroft JC, Williams HC. Translating patient-oriented eczema measure (POEM) scores into clinical practice by suggesting severity strata derived using anchor-based methods. Br J Dermatol. 2013;169(6):1326–32.CrossRef
9.
go back to reference Vakharia PP, Chopra R, Sacotte R, Patel N, Immaneni S, et al. Validation of patient-reported global severity of atopic dermatitis in adults. Allergy. 2018;73(2):451–8.CrossRef Vakharia PP, Chopra R, Sacotte R, Patel N, Immaneni S, et al. Validation of patient-reported global severity of atopic dermatitis in adults. Allergy. 2018;73(2):451–8.CrossRef
10.
go back to reference Lee JY, Kim M, Yang HK, Kim HM, Cho J, et al. Reliability and validity of the atopic dermatitis symptom score (ADSS). Pediatr Allergy Immunol. 2018;29(3):290–5.CrossRef Lee JY, Kim M, Yang HK, Kim HM, Cho J, et al. Reliability and validity of the atopic dermatitis symptom score (ADSS). Pediatr Allergy Immunol. 2018;29(3):290–5.CrossRef
11.
go back to reference Koh MJ, Giam YC, Liew HM, Foong AY, Chong JH, et al. Comparison of the simple patient-centric atopic dermatitis scoring system PEST with SCORAD in young children using a Ceramide dominant therapeutic moisturizer. Dermatol Ther (Heidelb). 2017;7(3):383–93.CrossRef Koh MJ, Giam YC, Liew HM, Foong AY, Chong JH, et al. Comparison of the simple patient-centric atopic dermatitis scoring system PEST with SCORAD in young children using a Ceramide dominant therapeutic moisturizer. Dermatol Ther (Heidelb). 2017;7(3):383–93.CrossRef
Metadata
Title
A caregiver-reported global severity assessment in pediatric atopic eczema: the Comano score
Authors
Mattia Giovannini
Davide Geat
Gabriele Barlocco
Riccardo Pertile
Francesca Mori
Cesare Filippeschi
Elio Novembre
Mario Cristofolini
Ermanno Baldo
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue 1/2020
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/s13052-020-0805-9

Other articles of this Issue 1/2020

Italian Journal of Pediatrics 1/2020 Go to the issue