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Published in: Child's Nervous System 3/2008

01-03-2008 | Case-based Update

Pilocytic astrocytoma developing at the site of a previously treated medulloblastoma in a child

Authors: Yavuz Koksal, Hatice Toy, Ekrem Unal, Tamer Baysal, Hasan Esen, Yahya Paksoy, M. Erkan Ustun

Published in: Child's Nervous System | Issue 3/2008

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Abstract

Background

After the achieved high cure rates, the survivors of medulloblastoma have come to face other complications associated with treatment regimes. One of these complications is secondary malignant neoplasm (SMN), which is rare but generally fatal.

Case history

We report a case of an 8-year-old girl in whom a pilocytic astrocytoma developed at the site of previously excised medulloblastoma 26 months earlier. The patient had then received postoperative radiotherapy and chemotherapy for the treatment of medulloblastoma. Twenty-five months after the cessation of treatment, she had no complaint and physical examination was unremarkable, but a mass in the operation region was detected. Surgical excision of the secondary pilocytic astrocytoma was performed with a good clinical recovery without any evidence of residue or recurrence at 9-month follow-up.

Conclusion

Clinicians must be vigilant for the risk of expected SMNs. Rigorous and prolonged follow-up of patients with central nervous system (CNS) tumors is warrant.
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Metadata
Title
Pilocytic astrocytoma developing at the site of a previously treated medulloblastoma in a child
Authors
Yavuz Koksal
Hatice Toy
Ekrem Unal
Tamer Baysal
Hasan Esen
Yahya Paksoy
M. Erkan Ustun
Publication date
01-03-2008
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 3/2008
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-007-0444-0

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