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Intensive Care Medicine
Published in: Intensive Care Medicine 5/2013

01-05-2013 | Correspondence

Pharmacokinetics of oseltamivir carboxylate in critically ill patients: each patient is unique

Authors: W. Kromdijk, M. A. Sikma, M. P. H. van den Broek, J. H. Beijnen, A. D. R. Huitema, D. W. de Lange

Published in: Intensive Care Medicine | Issue 5/2013

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Excerpt

Dear Editor, …
Literature
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Ariano RE, Sitar DS, Zelenitsky SA, Zarychanski R, Pisipati A, Ahern S, Kanji S, Rello J, Kumar A (2010) Enteric absorption and pharmacokinetics of oseltamivir in critically ill patients with pandemic (H1N1) influenza. CMAJ 182(4):357–363PubMedCrossRef
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Kromdijk W, Rosing H, van den Broek MP, Beijnen JH, Huitema AD (2012) Quantitative determination of oseltamivir and oseltamivir carboxylate in human fluoride EDTA plasma including the ex vivo stability using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 891–892:57–63PubMed
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Widmer N, Meylan P, Ivanyuk A, Aouri M, Decosterd LA, Buclin T (2010) Oseltamivir in seasonal, avian H5N1 and pandemic 2009 A/H1N1 influenza: pharmacokinetic and pharmacodynamic characteristics. Clin Pharmacokinet 49(11):741–765PubMedCrossRef
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Anderson GD (2005) Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach. Clin Pharmacokinet 44(10):989–1008PubMedCrossRef
Metadata
Title
Pharmacokinetics of oseltamivir carboxylate in critically ill patients: each patient is unique
Authors
W. Kromdijk
M. A. Sikma
M. P. H. van den Broek
J. H. Beijnen
A. D. R. Huitema
D. W. de Lange
Publication date
01-05-2013
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 5/2013
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-013-2851-x

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