Issue 1/2000
Content (11 Articles)
The applicability of computational chemistry in the evaluation and prediction of drug transport properties
Ulf Norinder, Thomas Österberg
Estimating log P with atom/fragments and water solubility with log P
William M. Meylan, Philip H. Howard
Estimating aqueous solvation and lipophilicity of small organic molecules: A comparative overview of atom/group contribution methods
Vellarkad N. Viswanadhan, Arup K. Ghose, John J. Wendoloski
Multiple computer-automated structure evaluation model of the plasma protein binding affinity of diverse drugs
Roustem D. Saiakhov, Liliana R. Stefan, Gilles Klopman
The influence of lipophilicity on the pharmacokinetic behavior of drugs: Concepts and examples
Bernard Testa, Patrizia Crivori, Marianne Reist, Pierre-Alain Carrupt