Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Abdominal Radiology
Published in: Abdominal Radiology 5/2008

01-09-2008

Peritumoral steatosis associated with insulinomas: appearance at imaging

Authors: Thomas D. Atwell, Ricardo V. Lloyd, David M. Nagorney, Jeff L. Fidler, James C. Andrews, Carl C. Reading

Published in: Abdominal Radiology | Issue 5/2008

Login to get access

Abstract

We report three patients with insulinoma tumors and distinct peritumoral steatosis, well demonstrated with several imaging modalities. This unique appearance can aid in pre-operative diagnosis and guide biopsy.
Literature
1.
Service FJ, et al. (1991) Functioning insulinoma-incidence, recurrence, and long-term survival of patients: a 60-year study. Mayo Clin Proc 66(7):711–719PubMed
2.
Brentjens R, Saltz L (2001) Islet cell tumors of the pancreas: the medical oncologist’s perspective. Surg Clin North Am 81(3):527–542PubMedCrossRef
3.
Fidler JL, et al. (2003) Preoperative detection of pancreatic insulinomas on multiphasic helical CT. AJR Am J Roentgenol 181(3):775–780PubMed
4.
Herwick S, Miller FH, Keppke AL (2006) MRI of islet cell tumors of the pancreas. AJR Am J Roentgenol 187(5):W472–W480PubMedCrossRef
5.
Hirshberg B, et al. (2005) Malignant insulinoma: spectrum of unusual clinical features. Cancer 104(2):264–272PubMedCrossRef
6.
Hashimoto LA, Walsh RM (1999) Preoperative localization of insulinomas is not necessary. J Am Coll Surg 189(4):368–373PubMedCrossRef
7.
Dromain C, et al. (2003) MR imaging of hepatic metastases caused by neuroendocrine tumors: comparing four techniques. AJR Am J Roentgenol 180(1):121–128PubMed
8.
Topping DL, Mayes PA (1972) The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism. Biochem J 126(2):295–311
9.
Eriguchi N, et al. (2000) Insulinoma occurring in association with fatty replacement of unknown etiology in the pancreas: report of a case. Surg Today 30(10):937–941PubMedCrossRef
10.
Hoshiba K, et al. (1997) Fatty infiltration of the liver distal to a metastatic liver tumor. Abdom Imaging 22(5):496–498PubMedCrossRef
11.
Sumiyoshi S, et al. (2005) Images of interest. Hepatobiliary and pancreatic: insulinoma metastases with focal hepatic steatosis. J Gastroenterol Hepatol 20(4):650PubMedCrossRef
12.
Sohn J, Siegelman E, Osiason A (2001) Unusual patterns of hepatic steatosis caused by the local effect of insulin revealed on chemical shift MR imaging. AJR Am J Roentgenol 176(2):471–474PubMed
13.
Fregeville A, et al. (2005) Metastatic insulinoma and glucagonoma from the pancreas responsible for specific peritumoral patterns of hepatic steatosis secondary to local effects of insulin and glucagon on hepatocytes. Gastroenterology 129(4):1150–1365PubMedCrossRef
14.
Khalili K, et al. (2003) Hepatic subcapsular steatosis in response to intraperitoneal insulin delivery: CT findings and prevalence. AJR Am J Roentgenol 180(6):1601–1604PubMed
Metadata
Title
Peritumoral steatosis associated with insulinomas: appearance at imaging
Authors
Thomas D. Atwell
Ricardo V. Lloyd
David M. Nagorney
Jeff L. Fidler
James C. Andrews
Carl C. Reading
Publication date
01-09-2008
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 5/2008
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-007-9278-1

Other articles of this Issue 5/2008

Abdominal Radiology 5/2008 Go to the issue

OriginalPaper

Complete penile corporeal septation: evaluation with contrast enhanced US

OriginalPaper

Paraumbilical collateral veins on MRI as possible protection against portal venous thrombosis in candidates for liver transplantation

OriginalPaper

Transcatheter chemoembolization in the treatment of HCC in patients not eligible for curative treatments: midterm results of doxorubicin-loaded DC bead

OriginalPaper

Giant jejunal ulcers after Roux-en-Y gastric bypass

OriginalPaper

Adult intestinal intussusception: can abdominal MDCT distinguish an intussusception caused by a lead point?

OriginalPaper

Ultrasound and fluoroscopy guided percutaneous transhepatic biliary drainage in patients with nondilated bile ducts
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits