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13-12-2023 | Peritoneal Dialysis | Original Article

Insight into prevalence, etiology, and modalities of pediatric chronic dialysis: a comprehensive nationwide analysis

Authors: Khalid Alhasan, Amro Attaf Alsalmi, Weiam Almaiman, Adi J. Al Herbish, Afrah Farhat, Ibrahim Sandokji, Majed Aloufi, Hassan Yahya Faqeehi, Naif Abdulmajeed, Abdulkarim Alanazi, Abdulaziz AlHassan, Abdulaziz Alshathri, Abeer Mohammad Almalki, Afaf Alawi Bafageeh, Ali M. Aldajani, Ashraf AlMuzain, Faten Sudan Almuteri, Haydar Hassan Nasser, Khalid Al Alsheikh, Khamisa Mohamed Almokali, Magbul Maghfuri, Mohamed Waleed Abukhatwah, Muawia Abdulla Mohamed Ahmed, Naeima Fatani, Naffaa Al-Harbi, Rezqah Fajor AlDhaferi, Sulaiman Amohaimeed, Zahra Hussain AlSannaa, Mohamed A. Shalaby, Rupesh Raina, Dieter Clemens Broering, Jameela A. Kari, Mohamad-Hani Temsah

Published in: Pediatric Nephrology | Issue 5/2024

Abstract

Background

This study aimed to determine the prevalence and etiology of kidney failure (KF) among children below 15 years of age receiving chronic dialysis in Saudi Arabia and describe their dialysis modalities.

Methods

This cross-sectional descriptive study was conducted on 8 August 2022, encompassing all 23 pediatric dialysis centers in Saudi Arabia. Data gathered comprised patient demographics, causes of KF, and the dialysis methods employed. Collected data underwent analysis to determine prevalence of children undergoing chronic dialysis, discern underlying causes of KF, and evaluate distribution of patients across different dialysis modalities.

Results

The prevalence of children on chronic dialysis is 77.6 per million children living in Saudi Arabia, equating to 419 children. The predominant underlying cause of KF was congenital anomalies of the kidneys and urinary tract (CAKUT), representing a substantial 41% of cases. Following this, others or unknown etiologies accounted for a noteworthy 25% of cases, with focal segmental glomerulosclerosis (FSGS) comprising 13%, glomerulonephritis at 11%, and congenital nephrotic syndrome contributing 10% to etiological distribution. Regarding dialysis modalities employed, 67% of patients were on peritoneal dialysis (PD), while the remaining 33% were on hemodialysis (HD).

Conclusions

This first nationwide study of pediatric chronic dialysis in Saudi Arabia sheds light on the prevalence of children undergoing chronic dialysis and underlying causes of their KF, thereby contributing to our understanding of clinical management considerations. This research serves as a stepping stone for the development of national registries.

Graphical abstract

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Title: Insight into prevalence, etiology, and modalities of pediatric chronic dialysis: a comprehensive nationwide analysis
Authors: Khalid Alhasan
Amro Attaf Alsalmi
Weiam Almaiman
Adi J. Al Herbish
Afrah Farhat
Ibrahim Sandokji
Majed Aloufi
Hassan Yahya Faqeehi
Naif Abdulmajeed
Abdulkarim Alanazi
Abdulaziz AlHassan
Abdulaziz Alshathri
Abeer Mohammad Almalki
Afaf Alawi Bafageeh
Ali M. Aldajani
Ashraf AlMuzain
Faten Sudan Almuteri
Haydar Hassan Nasser
Khalid Al Alsheikh
Khamisa Mohamed Almokali
Magbul Maghfuri
Mohamed Waleed Abukhatwah
Muawia Abdulla Mohamed Ahmed
Naeima Fatani
Naffaa Al-Harbi
Rezqah Fajor AlDhaferi
Sulaiman Amohaimeed
Zahra Hussain AlSannaa
Mohamed A. Shalaby
Rupesh Raina
Dieter Clemens Broering
Jameela A. Kari
Mohamad-Hani Temsah
Publication date: 13-12-2023
Publisher: Springer Berlin Heidelberg
Keywords: Peritoneal Dialysis
Glomerulonephritis
Nephrotic Syndrome
Published in: Pediatric Nephrology / Issue 5/2024
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-023-06245-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Insight into prevalence, etiology, and modalities of pediatric chronic dialysis: a comprehensive nationwide analysis

Abstract

Background

Methods

Results

Conclusions

Graphical abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

Graphical abstract

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