Published in:
01-09-2011 | Review Article
Periodontitis and diabetes—a complex relationship
Author:
Aparna Ramchandra Gharat
Published in:
International Journal of Diabetes in Developing Countries
|
Issue 3/2011
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Abstract
Periodontitis is a common problem in patients with diabetes. The interrelation between diabetes mellitus and inflammatory periodontal disease has been intensively studied for more than 50 years. The relationship between these 2 maladies appears bidirectional—insofar that the presence of one condition tends to promote the other, and that the meticulous management of either may assist treatment of the other. Inflammation plays an important role in this interrelation, orchestrating both the periodontal disease and diabetes mellitus pathogeny and complications. Conversely, periodontal infection can seriously impair metabolic control of some diabetic patients. Moreover, treatment of periodontal disease and reduction of oral signs of inflammation may have a beneficial effect on diabetes. This review examines the relationships that exist between periodontal diseases and diabetes mellitus, with a focus on potential common pathophysiologic pathways including those associated with inflammation, altered host responses and insulin resistance