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International Journal of Implant Dentistry
Published in: International Journal of Implant Dentistry 1/2020

01-12-2020 | Peri-Implant Diseases in the Maxillofacial Region | Research

Radiographic bone level around particular laser-treated dental implants: 1 to 6 years multicenter retrospective study

Authors: C. Mongardini, B. Zeza, P. Pelagalli, R. Blasone, M. Scilla, M. Berardini

Published in: International Journal of Implant Dentistry | Issue 1/2020

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Abstract

Purpose

The aim of the present retrospective study was to evaluate clinical and radiological outcomes, in terms of implant survival rate, marginal bone loss, and peri-implantitis incidence, of a titanium implants with an innovative laser-treated surface.

Materials and methods

A total of 502 dental implants were inserted in four dental practices (Udine, Arezzo, Frascati, Roma) between 2008 and 2013. All inserted implants had laser-modified surface characterized by a series of 20-μm-diameter holes (7–10 μm deep) every 10 μm (Synthegra®, Geass srl, Italy). The minimum follow-up period was set at 1 year after the final restoration. Radiographs were taken after implant insertion (T0), at time of loading (T1), and during the follow-up period (last recall, T2). Marginal bone loss and peri-implant disease incidence were recorded.

Results

A total of 502 implants with a maximum follow-up period of 6 years were monitored. The mean differential between T0 and T2 was 0.05 ± 1.08 mm at the mesial aspect and 0.08 ± 1.11 mm at the distal with a mean follow-up period of 35.76 ± 18.05 months. After being in function for 1 to 6 years, implants reported varying behavior: 8.8% of sites did not show any radiographic changes and 38.5% of sites showed bone resorption. The bone appeared to have been growing coronally in 50.7% of the sites measured.

Conclusion

Implants showed a maintenance of marginal bone levels over time, and in many cases, it seems that laser-modified implant surface could promote a bone growth. The low peri-implant disease incidence recorded could be attributed to the laser titanium surface features that seem to prevent bacterial colonization. Future randomized and controlled studies are needed to confirm the results of the present multi-centrical retrospective analysis.
Literature
1.
Adler L, Buhlin K, Jansson L. Survival and complications: A 9- to 15-year retrospective follow-up of dental implant therapy. J Oral Rehabil. 2020;47:67–77.
2.
Sinjari B, D'Addazio G, Traini T, Varvara G, Scarano A, Murmura G, Caputi S. A 10-year retrospective comparative human study on screw-retained versus cemented dental implant abutments. J Biol Regul Homeost Agents. 2019;33:787–97.PubMed
3.
Salman A, Thacker S, Rubin S, Dhingra A, Ioannidou E, Schincaglia GP. Immediate versus delayed loading of mandibular implant-retained overdentures: a 60-month follow-up of a randomized clinical trial. J Clin Periodontol. 2019;46:863–71.PubMed
4.
Gallardo YNR, da Silva-Olivio IR, Gonzaga L, Sesma N, Martin W. A systematic review of clinical outcomes on patients rehabilitated with complete-arch fixed implant-supported prostheses according to the time of loading. J Prosthodont. 2019 Aug;21.
5.
Lemos CAA, Verri FR, Gomes JML, de Souza Batista VE, Cruz RS, Oliveira HFFE, Pellizzer EP. Ceramic versus metal-ceramic implant-supported prostheses: a systematic review and meta-analysis. J Prosthet Dent. 2019;121:879–886.e4.PubMed
6.
Ducommun J, El Kholy K, Rahman L, Schimmel M, Chappuis V, Buser D. Analysis of trends in implant therapy at a surgical specialty clinic: patient pool, indications, surgical procedures, and rate of early failures-a 15-year retrospective analysis. Clin Oral Implants Res. 2019;30(11):1097–106.PubMed
7.
Dreyer H, Grischke J, Tiede C, Eberhard J, Schweitzer A, Toikkanen SE, Glöckner S, Krause G, Stiesch M. Epidemiology and risk factors of peri-implantitis: a systematic review. J Periodontal Res. 2018;53:657–81.PubMed
8.
Bevilacqua L, Milan A, Del Lupo V, Maglione M, Dolzani L. Biofilms developed on dental implant titanium surfaces with different roughness: comparison between in vitro and in vivo studies. Curr Microbiol. 2018;75:766–72.PubMed
9.
Berglundh T, Persson L, Klinge B. A systematic review of the incidence of biological and technical complications in implant dentistry reported in prospective longitudinal studies of at least 5 years. J Clin Periodontol. 2002;29(Suppl. 3):197–212.PubMed
10.
Doornewaard R, Christiaens V, De Bruyn H, Jacobsson M, Cosyn J, Vervaeke S, Jacquet W. Long-term effect of surface roughness and patients’ factors on crestal bone loss at dental implants. A systematic review and meta-analysis. Clin Implant Dent Relat Res. 2017;19:372–99.PubMed
11.
De Bruyn H, Vandeweghe S, Ruyffelaert C, Cosyn J, Sennerby L. Radiographic evaluation of modern oral implants with emphasis on crestal bone level and relevance to peri-implant health. Periodontol 2000. 2013;62(1):256–70.PubMed
12.
Albrektsson T, Dahlin C, Jemt T, Sennerby L, Turri A, Wennerberg A. Is marginal bone loss around oral implants the result of a provoked foreign body reaction? Clin Implant Dent Relat Res. 2014;16(2):155–65.PubMed
13.
Tatarakis N, Bashutski J, Wang HL, Oh TJ. Early implant bone loss: preventable or inevitable? Implant Dent. 2012;21(5):379–86.PubMed
14.
De Bruyn H, Christiaens V, Doornewaard R, Jacobsson M, Cosyn J, Jacquet W, Vervaeke S. Implant surface roughness and patient factors on long-term peri-implant bone loss. Periodontol 2000. 2017;73:218–27.PubMed
15.
Park YS, Lee SP, Han CH, Kwon JH, Jung YC. The microtomographic evaluation of marginal bone resorption of immediately loaded scalloped design implant with various microthread configurations in canine mandible: pilot study. J Oral Implantol. 2010;36:357–62.PubMed
16.
Caricasulo R, Malchiodi L, Ghensi P, Fantozzi G, Cucchi A. The influence of implant-abutment connection to peri-implant bone loss: a systematic review and meta-analysis. Clin Implant Dent Relat Res. 2018;20:653–64.PubMed
17.
Javed F, Romanos GE. Chronic hyperglycemia as a risk factor in implant therapy. Periodontol 2000. 2019;81:57–63.PubMed
18.
Javed F, Rahman I, Romanos GE. Tobacco-product usage as a risk factor for dental implants. Periodontol 2000. 2019;81:48–56.PubMed
19.
Lee D, Sohn B, Kim KH, Kim S, Koo KT, Kim TI, Seol YJ, Lee YM, Rhyu IC, Ku Y. Effects of untreated periodontitis on osseointegration of dental implants in a Beagle Dog Model. J Periodontol. 2016;87:1141–8.PubMed
20.
Trisi P, Berardini M, Falco A, Podaliri VM. New osseodensification implant site preparation method to increase bone density in low-density bone: in vivo evaluation in sheep. Implant Dent. 2016;25:24–31.PubMedPubMedCentral
21.
Nicolielo LFP, Van Dessel J, Jacobs R, Quirino Silveira Soares M, Collaert B. Relationship between trabecular bone architecture and early dental implant failure in the posterior region of the mandible. Clin Oral Implants Res. 2020;31:153–61.
22.
Trisi P, Berardini M, Falco A, Podaliri VM. Effect of implant thread geometry on secondary stability, bone density, and bone-to-implant contact: a biomechanical and histological analysis. Implant Dent. 2015;24:384–91.PubMed
23.
Yang J, Zhou Y, Wei F, Xiao Y. Blood clot formed on rough titanium surface induces early cell recruitment. Clin Oral Implants Res. 2016;27:1031–8.PubMed
24.
Wennerberg A. Albrektsson T Effects of titanium surface topography on bone integration: a systematic review. Clin Oral Implants Res. 2009;4:172–84.
25.
Trisi P, Berardini M, Falco A, Sandrini E, Vulpiani MP. A new highly hydrophilic electrochemical implant titanium surface: a histological and biomechanical in vivo study. Implant Dent. 2017;26:429–37.PubMed
26.
Smeets R, Stadlinger B, Schwarz F, Beck-Broichsitter B, Jung O, Precht C, Kloss F, Gröbe A, Heiland M, Ebker T. Impact of dental implant surface modifications on osseointegration. Biomed Res Int. 2016;2016:6285620.PubMedPubMedCentral
27.
Berardi D, Colagiovanni M, Scoccia A, Raffaelli L, Manicone PF, Perfetti G. Evaluation of a new laser surface implant: scanning electron microscopy/energy dispersive X-ray and X-ray photoelectron spectroscopy analyses. J Biol Regul Homeost Agents. 2008;22:161–7.PubMed
28.
Drago L, Bortolin M, De Vecchi E, Agrappi S, Weinstein RL, Mattina R, Francetti L. Antibiofilm activity of sandblasted and laser-modified titanium against microorganisms isolated from peri-implantitis lesions. J Chemother. 2016;28:383–9.PubMed
29.
Cei S, Karapetsa D, Aleo E, Graziani F. Protein adsorption on a laser-modified titanium implant surface. Implant Dentistry. 2015;24:134–41.PubMed
30.
Misch CE, Perel ML, Wang HL, Sammartino G, Galindo-Moreno P, Trisi P, Steigmann M, Rebaudi A, Palti A, Pikos MA, Schwartz-Arad D, Choukroun J, Gutierrez-Perez JL, Marenzi G, Valavanis DK. Implant success, survival, and failure: the International Congress of Oral Implantologists (ICOI) Pisa Consensus Conference. Implant Dent. 2008 Mar;17(1):5–15.PubMed
31.
Zeza B, Pilloni A, Tatakis DN, Mariotti A, Di Tanna GL, Mongardini C. Implant patient compliance varies by periodontal treatment history. J Periodontol. 2017;88(9):846–53.PubMed
32.
Sammons RL, Lumbikanonda N, Gross M, Cantzler P. Comparison of osteoblast spreading on microstructured dental implant surfaces and cell behavior in an explant model of osseointegration. A scanning electron microscopic study. Clin Oral Implants Res. 2005;16:657–66.PubMed
33.
Zhao G, Raines AL, Wieland M, Schwartz Z, Boyan BD. Requirement for both micron- and submicron scale structure for synergistic responses of osteoblasts to substrate surface energy and topography. Biomaterials. 2007;28:2821–9.PubMedPubMedCentral
34.
Adell R, Lekholm U, Rockler B, Brånemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg. 1981;10:387–416.PubMed
35.
Francetti L, Romeo D, Corbella S, Taschieri S, Del Fabbro M. Bone level changes around axial and tilted implants in full-arch fixed immediate restorations. Interim results of a prospective study. Clin Implant Dent Relat Res. 2012;14:646–54.PubMed
36.
Felice P, Barausse C, Blasone R, Favaretto G, Stacchi C, Calvo M, Marin C, Buti J, Esposito M. A comparison of two dental implant systems in partially edentulous patients: 1-year post-loading results from a pragmatic multicentre randomised controlled trial. Eur J Oral Implantol. 2014;7(4):397–409.PubMed
37.
Zuffetti F, Testarelli L, Bertani P, Vassilopoulos S, Testori T, Guarnieri R. A retrospective multicenter study on short implants with a laser-microgrooved collar (≤7.5 mm) in posterior edentulous areas: radiographic and clinical results up to 3 to 5 years. J Oral Maxillofac Surg. 2020;78:217–27.
38.
Acharya A, Leung MCT, Ng KT, Fan MHM, Fokas G, Mattheos N. Peri-implant marginal bone loss rate pre- and post-loading: an exploratory analysis of associated factors. Clin Oral Implants Res. 2019;30:410–9.PubMed
39.
Laurell L, Lundgren D. Marginal bone level changes at dental implants after 5 years in function: a meta-analysis. Clin Implant Dent Relat Res. 2011;13(1):19–28.PubMed
40.
Vervaeke S, Collaert B, Cosyn J, Deschepper E, De Bruyn H. A multifactorial analysis to identify predictors of implant failure and peri-implant bone loss. Clin Implant Dent Relat Res. 2015;17(Suppl 1):e298–307.PubMed
41.
Del Fabbro M, Ceresoli V. The fate of marginal bone around axial vs. tilted implants: a systematic review. Eur J Oral Implantol. 2014;7(Suppl 2):S171–89.PubMed
42.
Sinjari B, Traini T, Caputi S, Mortellaro C, Scarano A. Evaluation of fibrin clot attachment on titanium laser-conditioned surface using scanning electron microscopy. J Craniofac Surg. 2018;29:2277–81.PubMed
43.
Quabius ES, Ossenkop L, Harder S, Kern M. Dental implants stimulate expression of Interleukin-8 and its receptor in human blood--an in vitro approach. J Biomed Mater Res B Appl Biomater. 2012;100(5):1283–8.PubMed
44.
Salvi GE, Aglietta M, Eick S, Sculean A, Lang NP, Ramseier CA. Reversibility of experimental peri-implant mucositis compared with experimental gingivitis in humans. Clin Oral Implant Res. 2012;23:182–90.
45.
Aguirre-Zorzano LA, Vallejo-Aisa FJ, Estefanía-Fresco R. Supportive periodontal therapy and periodontal biotype as prognostic factors in implants placed in patients with a history of periodontitis. Med Oral Patol Oral Cir Bucal. 2013;18(5):e786–92.PubMedPubMedCentral
46.
Albrektsson T, Zarb GA. Current interpretations of the osseointegrated response: clinical significance. Int J Prosthodont. 1993;6(2):95–105.PubMed
47.
Trisi P, Berardini M, Colagiovanni M, Berardi D, Perfetti G. Laser-treated titanium implants: an in vivo histomorphometric and biomechanical analysis. Implant Dent. 2016;25:575–80.PubMed
48.
De Tullio I, Berardini M, Di Iorio D, Perfetti F, Perfetti G. Comparative evaluation among laser-treated, machined, and sandblasted/acid-etched implant surfaces: an in vivo histologic analysis on sheep. Int J Implant Dent. 2020;6(1):7.
49.
Krebs M, Kesar N, Begić A, von Krockow N, Nentwig GH, Weigl P. Incidence and prevalence of peri-implantitis and peri-implant mucositis 17 to 23 (18.9) years postimplant placement. Clin Implant Dent Relat Res. 2019;21:1116–23.PubMed
50.
Pjetursson BE, Thoma D, Jung R, Zwahlen M, Zembic A. A systematic review of the survival and complication rates of implant-supported fixed dental prostheses (FDPs) after a mean observation period of at least 5 years. Clin Oral Implants Res. 2012;23(Suppl 6):22–38.PubMed
51.
Pandolfi A, Rinaldo F, Pasqualotto D, Sorrentino F, La Torre G, Guerra F. A retrospective cohort study on peri-implant complications in implants up to 10 years of functional loading in periodontally compromised patients. J Periodontol. 2019;10.1002/JPER.18-0715. [Published online ahead of print, 2019 Dec 20].
52.
Di Giulio M, Traini T, Sinjari B, Nostro A, Caputi S, Cellini L. Porphyromonas gingivalis biofilm formation in different titanium surfaces, an in vitro study. Clin Oral Implants Res. 2016 Jul;27(7):918–25.PubMed
53.
Ionescu AC, Brambilla E, Azzola F, Ottobelli M, Pellegrini G, Francetti LA. Laser microtextured titanium implant surfaces reduce in vitro and in situ oral biofilm formation. PLoS One. 2018;13:e0202.
54.
Gracis S, Michalakis K, Vigolo P, Vult von Steyern P, Zwahlen M, Sailer I. Internal vs. external connections for abutments/reconstructions: a systematic review. Clin Oral Implants Res. 2012;23(Suppl 6):202–16.PubMed
55.
Lazzara RJ, Porter SS. Platform switching: a new concept in implant dentistry for controlling postrestorative crestal bone levels. Int J Periodontics Restorative Dent. 2006;26:9–17.PubMed
Metadata
Title
Radiographic bone level around particular laser-treated dental implants: 1 to 6 years multicenter retrospective study
Authors
C. Mongardini
B. Zeza
P. Pelagalli
R. Blasone
M. Scilla
M. Berardini
Publication date
01-12-2020
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Implant Dentistry / Issue 1/2020
Electronic ISSN: 2198-4034
DOI
https://doi.org/10.1186/s40729-020-00230-w

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