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Published in: International Journal of Implant Dentistry 1/2020

01-12-2020 | Sinus Lift | Research

Comparison of two anorganic bovine bone in maxillary sinus lift: a split-mouth study with clinical, radiographical, and histomorphometrical analysis

Authors: Heitor Fontes da Silva, Douglas Rangel Goulart, Alexander Tadeu Sverzut, Sergio Olate, Márcio de Moraes

Published in: International Journal of Implant Dentistry | Issue 1/2020

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Abstract

Background

Anorganic bovine bone (Bio-Oss®) has been extensively used for reconstruction of posterior area of maxilla in sinus lift procedure; however, a new graft material (Lumina-Bone Porous®), that has a different manufacturing process, has not been yet compared in clinical and histological terms. The manufacturing process of bovine bone graft is related to size and porosity of the particles, and this can change osteoconductive property of the material and bone formation. The use of Lumina-Porus® could improve bone formation, reduce the remaining particles of the biomaterial using a low-cost material. The aim of this research was to compare the clinical, radiological, and histomorphometrical results from maxillary sinus lift with two different anorganic bovine bone substitutes Bio-Oss® (control) and Lumina-Bone Porous® (test).

Results

A split-mouth study was performed with 13 volunteers. The mean bone ridge height in the deepest portion of maxillary sinuses floor was 3.11 ± 0.83 mm in the Bio-Oss® and 2.38 ± 0.75 mm in the Lumina-Bone Porous®. After sinus lift, the Bio-Oss® group shows bone ridge height of 11.56 ± 2.03 mm and Lumina-Bone® of 10.62 ± 1.93 mm. The increase in alveolar bone height scores was significant between pre-augmentation and 6 months after SL in both groups (p < 0.001). No statistical significant difference in newly formed bone in the Bio-Oss® group (20.4 ± 5.4%), and Lumina-Bone Porous® (22.8 ± 8.5%) was histomorphological observed (p > 0.05). On the other hand, the residual graft particles showed significant difference between the Bio-Oss® group (19.9 ± 8.6%) and Lumina-Bone Porous® (14.6 ± 5.6%) (p < 0.05). The survival rate of dental implants for augmented area with Lumina Bone Porous® was 88.88%, while for Bio-Oss® group was 100%.

Conclusion

Both materials Bio-Oss® and Lumina-Bone Porous® can be used in the maxillary sinus floor augmentation with good predictability in clinical, radiographical, and histological point of view.
Literature
6.
go back to reference Schwartz Z, Weesner T, van Dijk S, Cochran DL, Mellonig JT, Lohmann CH, Carnes DL, Goldstein M, Dean DD, Boyan BD. Ability of deproteinized cancellous bovine bone to induce new bone formation. J Periodontol. 2000;71(8):1258–69.CrossRef Schwartz Z, Weesner T, van Dijk S, Cochran DL, Mellonig JT, Lohmann CH, Carnes DL, Goldstein M, Dean DD, Boyan BD. Ability of deproteinized cancellous bovine bone to induce new bone formation. J Periodontol. 2000;71(8):1258–69.CrossRef
11.
go back to reference Saklad M. Grading of patients for surgical procedures. Anesthesiology. 1941;2:281–4.CrossRef Saklad M. Grading of patients for surgical procedures. Anesthesiology. 1941;2:281–4.CrossRef
12.
go back to reference Tatum H Jr. Maxillary and sinus implant reconstructions. Dentistry Clinical North America. 1986;30:207–29. Tatum H Jr. Maxillary and sinus implant reconstructions. Dentistry Clinical North America. 1986;30:207–29.
13.
go back to reference Aa H, Sbm P, Kohal RJ, Gubik S, Strohl C, Stampf S, Alexander A, Maria B. Effect of two different healing times on the mineralization of newly formed bone using a bovine bone substitute in sinus floor augmentation: a randomized , controlled , clinical and histological investigation; 2015. p. 1052. Aa H, Sbm P, Kohal RJ, Gubik S, Strohl C, Stampf S, Alexander A, Maria B. Effect of two different healing times on the mineralization of newly formed bone using a bovine bone substitute in sinus floor augmentation: a randomized , controlled , clinical and histological investigation; 2015. p. 1052.
14.
go back to reference Tanaka H, Toyoshima T, Atsuta I, Ayukawa Y, Sasaki M, Matsushita Y, Hiraoka R, Koyano K, Nakamura S. Additional effects of platelet-rich fibrin on bone regeneration in sinus augmentation with deproteinized bovine bone mineral: preliminary results. Implant Dent. 2015. Tanaka H, Toyoshima T, Atsuta I, Ayukawa Y, Sasaki M, Matsushita Y, Hiraoka R, Koyano K, Nakamura S. Additional effects of platelet-rich fibrin on bone regeneration in sinus augmentation with deproteinized bovine bone mineral: preliminary results. Implant Dent. 2015.
15.
go back to reference Maniatopoulos C, Rodriguez A, Deporter DA, Melcher AH. An improved method for preparing histological sections of metallic implants. Int J Oral Maxillo Fac Implants. 1986;1:31–7. Maniatopoulos C, Rodriguez A, Deporter DA, Melcher AH. An improved method for preparing histological sections of metallic implants. Int J Oral Maxillo Fac Implants. 1986;1:31–7.
16.
go back to reference Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Rec-Ker RR. Bone histomorphometry: stan- dardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Mineral Res. 1987;2:595–610.CrossRef Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Rec-Ker RR. Bone histomorphometry: stan- dardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Mineral Res. 1987;2:595–610.CrossRef
17.
go back to reference Silva HF, Abuna RPF, Lopes HB, Francischini MS, de Oliveira PT, Rosa AL, Beloti MM. Participation of extracellular signal-regulated kinases 1/2 in osteoblast and adipocyte differentiation of mesenchymal stem cells grown on titanium surfaces. Eur J Oral Sci. 2017;125(5):355–60. https://doi.org/10.1111/eos.12369.CrossRefPubMed Silva HF, Abuna RPF, Lopes HB, Francischini MS, de Oliveira PT, Rosa AL, Beloti MM. Participation of extracellular signal-regulated kinases 1/2 in osteoblast and adipocyte differentiation of mesenchymal stem cells grown on titanium surfaces. Eur J Oral Sci. 2017;125(5):355–60. https://​doi.​org/​10.​1111/​eos.​12369.CrossRefPubMed
18.
go back to reference Rosa AL, Kato RB, Castro Raucci LM, Teixeira LN, de Oliveira FS, Bellesini LS, de Oliveira PT, Hassan MQ, Beloti MM. Nanotopography drives stem cell fate toward osteoblast differentiation through α1β1 integrin signaling pathway. J Cell Biochem. 2014;115(3):540–8. https://doi.org/10.1002/jcb.24688.CrossRefPubMed Rosa AL, Kato RB, Castro Raucci LM, Teixeira LN, de Oliveira FS, Bellesini LS, de Oliveira PT, Hassan MQ, Beloti MM. Nanotopography drives stem cell fate toward osteoblast differentiation through α1β1 integrin signaling pathway. J Cell Biochem. 2014;115(3):540–8. https://​doi.​org/​10.​1002/​jcb.​24688.CrossRefPubMed
19.
20.
21.
go back to reference Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral Maxillofac Implants. 2009;24(Suppl):237–59.PubMed Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral Maxillofac Implants. 2009;24(Suppl):237–59.PubMed
22.
23.
go back to reference Schlegel KA, Fichtner G, Schultze-Mosgau S, Wiltfang J. Histologic findings in sinus augmentation with autogenous bone chips versus a bovine bone substitute. Int J Oral Maxillofac Implants. 2003;18:53–8.PubMed Schlegel KA, Fichtner G, Schultze-Mosgau S, Wiltfang J. Histologic findings in sinus augmentation with autogenous bone chips versus a bovine bone substitute. Int J Oral Maxillofac Implants. 2003;18:53–8.PubMed
24.
go back to reference Al-Nawas B, Schiegnitz E. Augmentation procedures using bone substitute materials or autogenous bone – a systematic review and meta-analysis. Eur J Oral Implantol. 2014;7(Suppl2):S219–34.PubMed Al-Nawas B, Schiegnitz E. Augmentation procedures using bone substitute materials or autogenous bone – a systematic review and meta-analysis. Eur J Oral Implantol. 2014;7(Suppl2):S219–34.PubMed
26.
27.
go back to reference Klüppel LE, Antonini F, Olate S, Nascimento FF, Albergaria-Barbosa JR, Mazzonetto R. Bone repair is influenced by different particle sizes of anorganic bovine bone matrix: a histologic and radiographic study in vivo. J Craniofac Surg. 2013;24:1074–7.CrossRef Klüppel LE, Antonini F, Olate S, Nascimento FF, Albergaria-Barbosa JR, Mazzonetto R. Bone repair is influenced by different particle sizes of anorganic bovine bone matrix: a histologic and radiographic study in vivo. J Craniofac Surg. 2013;24:1074–7.CrossRef
28.
go back to reference John HD, Wenz B. Histomorphometric analysis of natural bone mineral for maxillary sinus floor augmentation. Int J Oral Maxillofac Implants. 2004;19:199–207.PubMed John HD, Wenz B. Histomorphometric analysis of natural bone mineral for maxillary sinus floor augmentation. Int J Oral Maxillofac Implants. 2004;19:199–207.PubMed
29.
go back to reference Froum SJ, Wallace SS, Elian N, Cho SC, Tarnow DP. Comparison of mineralized cancellous boné allograft (puros) and anorganic bovine boné matrix (Bio-Oss®) for sinus augmen- tation: histomorphometry at 26–32 weeks after grafting. Int J Periodontics Restorative Dent. 2006;26:543–51.PubMed Froum SJ, Wallace SS, Elian N, Cho SC, Tarnow DP. Comparison of mineralized cancellous boné allograft (puros) and anorganic bovine boné matrix (Bio-Oss®) for sinus augmen- tation: histomorphometry at 26–32 weeks after grafting. Int J Periodontics Restorative Dent. 2006;26:543–51.PubMed
30.
go back to reference Di Stefano DA, Gastaldi G, Vinci R, Cinci L, Pieri L, Gherlone E. Histomorphometric comparison of enzyme-deantigenic equine bone and anorganic bovine bone in sinus augmentation: a randomized clinical trial with 3-year follow-up. Int J Oral Maxillofac Implants. 2015;30(5):1161–7. https://doi.org/10.11607/jomi.4057.CrossRefPubMed Di Stefano DA, Gastaldi G, Vinci R, Cinci L, Pieri L, Gherlone E. Histomorphometric comparison of enzyme-deantigenic equine bone and anorganic bovine bone in sinus augmentation: a randomized clinical trial with 3-year follow-up. Int J Oral Maxillofac Implants. 2015;30(5):1161–7. https://​doi.​org/​10.​11607/​jomi.​4057.CrossRefPubMed
31.
go back to reference Parra M, Atala-Acevedo C, Fariña R, Haidar ZS, Zaror C, Olate S. Graftless maxillary sinus lift using lateral window approach: a systematic review. Implant Dent. 2018;27:111–8.CrossRef Parra M, Atala-Acevedo C, Fariña R, Haidar ZS, Zaror C, Olate S. Graftless maxillary sinus lift using lateral window approach: a systematic review. Implant Dent. 2018;27:111–8.CrossRef
32.
go back to reference Parra M, Olate S, Cantin M. Clinical and biological analysis in graftless maxillary sinus lift. J Korean Assoc Oral Maxillofac Surg. 2017;43:214–20.CrossRef Parra M, Olate S, Cantin M. Clinical and biological analysis in graftless maxillary sinus lift. J Korean Assoc Oral Maxillofac Surg. 2017;43:214–20.CrossRef
Metadata
Title
Comparison of two anorganic bovine bone in maxillary sinus lift: a split-mouth study with clinical, radiographical, and histomorphometrical analysis
Authors
Heitor Fontes da Silva
Douglas Rangel Goulart
Alexander Tadeu Sverzut
Sergio Olate
Márcio de Moraes
Publication date
01-12-2020
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Implant Dentistry / Issue 1/2020
Electronic ISSN: 2198-4034
DOI
https://doi.org/10.1186/s40729-020-00214-w

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