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Published in: Pediatric Radiology 5/2013

01-05-2013 | Original Article

Percutaneous CT-guided vertebral bone biopsy in children

Authors: Deddeh Ballah, Els Nijs, Marc S. Keller, Xiaowei Zhu, Ganesh Krishnamurthy, Anne Marie Cahill

Published in: Pediatric Radiology | Issue 5/2013

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Abstract

Background

Few published series are dedicated solely to CT-guided vertebral bone biopsy in children.

Objective

The objective of our study was to review the diagnostic yield of CT-guided vertebral bone biopsy in children.

Materials and methods

A retrospective review of 26 consecutive CT-guided vertebral bone biopsies during a 7-year period in 24 children (16 girls and 8 boys), mean age 8.8 years (range 1–16 years) was performed at our institution. Procedures were reviewed for diagnostic accuracy, biopsy location, complications and final diagnosis.

Results

Twenty-five of 26 biopsies (96%) were technically successful. Twenty-one of 26 biopsies were diagnostic (81%); 2/26 (8%) were false-negative removing non-lesional tissue, 2/26 (8%) were nondiagnostic, and 1/26 (4%) was technically unsuccessful. The diagnoses were as follows: 12/26 biopsies (46%) were osteomyelitis, 3/26 (11%) biopsies were Langerhans cell histiocytosis, 3/26 biopsies (11%) were normal bone, 2/26 (8%) biopsies were malignant tumors, and 1/26 (4%) biopsies was osteoblastoma. There was one self-limited, procedure-related complication: a small right-sided pneumothorax occurred in the setting of attempting to create a protective extrapleural biopsy window.

Conclusion

Percutaneous CT-guided vertebral bone biopsy can be performed safely in children with a high degree of diagnostic accuracy.
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Metadata
Title
Percutaneous CT-guided vertebral bone biopsy in children
Authors
Deddeh Ballah
Els Nijs
Marc S. Keller
Xiaowei Zhu
Ganesh Krishnamurthy
Anne Marie Cahill
Publication date
01-05-2013
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 5/2013
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-012-2542-8

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