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Published in:

01-04-2007 | Original Article

Image-guided percutaneous biopsy of musculoskeletal lesions in children

Authors: Hyun-Joon Shin, Joao G. Amaral, Derek Armstrong, Peter G. Chait, Michael J. Temple, Philip John, Charles R. Smith, Glenn Taylor, Bairbre L. Connolly

Published in: Pediatric Radiology | Issue 4/2007

Abstract

Background

Percutaneous core needle biopsy (PCNB) of musculoskeletal lesions can provide early and definitive diagnosis and guide decisions on management. The technique is less invasive than open biopsy and has a low complication rate.

Objectives

The purpose of this study was to assess the diagnostic accuracy and safety of image-guided PCNB of musculoskeletal lesions in children.

Materials and methods

Retrospective review of the medical records of patients referred for PCNB of musculoskeletal lesions was performed. Data collected included tumor type and complication rates. Lesion “hit” or “missed”, and core adequacy and ability to reach a definitive pathological diagnosis were reviewed and used to determine whether the biopsy was overall successful or unsuccessful.

Results

A total of 127 biopsies were performed in 111 patients. Of the 127 PCNB procedures, 114 “hit” the lesion and 13 “missed,” and 120 of the cores provided for analysis were deemed adequate for pathological interpretation and 7 were deemed inadequate. A definitive pathological diagnosis was possible in 97 of the 127 PCNB preocedures and not possible in 30. Overall 76% of the PCNB procedures were successful. The diagnostic success of biopsy in primary malignant tumors was significantly higher (92%) than in primary benign tumors (65%; P = 0.008). Six minor complications resulted from PCNB.

Conclusion

This study showed that PCNB is accurate and safe for the diagnosis of musculoskeletal lesions in pediatric patients, and its results are comparable to those in adult studies.

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Title: Image-guided percutaneous biopsy of musculoskeletal lesions in children
Authors: Hyun-Joon Shin
Joao G. Amaral
Derek Armstrong
Peter G. Chait
Michael J. Temple
Philip John
Charles R. Smith
Glenn Taylor
Bairbre L. Connolly
Publication date: 01-04-2007
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 4/2007
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-007-0421-5

At a glance: The STEP trials

Springer Medicine

Image-guided percutaneous biopsy of musculoskeletal lesions in children

Abstract

Background

Objectives

Materials and methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Objectives

Materials and methods

Results

Conclusion

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