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Pediatric Intensive Care

Mediastinal mass of twice an infant’s bodyweight

Giant anterior mediastinal masses pose unique challenges for resection, such as cardiovascular collapse on induction of anesthesia and injury to surrounding structures that may be compressed or displaced.

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Editor's Choice

Dislodged PICC tip causing acute respiratory failure

Complications from peripheral IV central catheters can be difficult to identify quickly in pediatric patients. Point-of-care ultrasound showed a massive pleural effusion in this infant.

Severe cobalamin C deficiency

Nephrotic syndrome is usually caused by primary renal disorders, but you should consider metabolic diseases in atypical cases. This 7-month-old presented with nephrotic syndrome, malignant hypertension, and hemolytic anemia.

Caring for ultra-low birthweight infants

Explore the unique challenges in thermoregulation, incubator humidity, and skincare practices in infants weighing less than 500 g at birth (usually ≤23 weeks gestation).

Neonatal meningitis: new and old lessons

A premature infant presented with extensive CNS injury from recurrent E. coli infection, requiring non-traditional methods to identify and clear the infection.

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Case Studies

Mediastinal mass of twice an infant’s bodyweight

Giant anterior mediastinal masses pose unique challenges for resection, such as cardiovascular collapse on induction of anesthesia and injury to surrounding structures that may be compressed or displaced.

Dislodged PICC tip causing acute respiratory failure

Complications from peripheral IV central catheters can be difficult to identify quickly in pediatric patients. Point-of-care ultrasound showed a massive pleural effusion in this infant.

Severe cobalamin C deficiency

Nephrotic syndrome is usually caused by primary renal disorders, but you should consider metabolic diseases in atypical cases. This 7-month-old presented with nephrotic syndrome, malignant hypertension, and hemolytic anemia.

Current Reviews

Post-traumatic stress disorder in children after discharge from the pediatric intensive care unit: a scoping review

As the prevalence of post-traumatic stress disorder (PTSD) among children discharged from pediatric intensive care unit (PICU) continues to rise, corresponding research efforts have also increased. This scoping review aimed to review the PTSD …

Point-of-care abdominal ultrasound in pediatric and neonatal intensive care units

A spectrum of critical abdominal pathological conditions that might occur in neonates and children warrants real-time point-of-care abdominal ultrasound (abdominal POCUS) assessment. Abdominal radiographs have limited value with low sensitivity …

The Opportunities and Challenges for Artificial Intelligence to Improve Sepsis Outcomes in the Paediatric Intensive Care Unit

Sepsis is a life-threatening condition characterised by organ dysfunction in response to a dysregulated immune response to infection [ 1 ]. It is a global health priority estimated to cause 2.9 million deaths in children under 5 each year [ 2 ].

Analgesia and sedation in critically ill pediatric patients: an update from the recent guidelines and point of view

In the last decades, the advancement of knowledge in analgesia and sedation for critically ill pediatric patients has been conspicuous and relevant. Many recommendations have changed to ensure patients’ comfort during their intensive care unit …

Further Reading

Drug–Drug Interactions Involving High-Alert Medications that Lead to Interaction-Associated Symptoms in Pediatric Intensive Care Patients: A Retrospective Study

Children admitted to a pediatric intensive care unit (PICU) are often in a critical state of health and require complex drug treatment. Although administration of multiple drugs together leads to an increased risk of drug-related problems [ 1 , 2 …

Significance of colonization by antibiotic-resistant organisms prior to congenital heart disease surgery in children from low- to middle-income countries sent by non-governmental organizations to Switzerland

Antibiotic-resistant microorganisms (AMROs) colonization rate in patients from low- to middle-income countries (LMIC) has been reported to be high, reaching 50% or more depending on the bacterial species [ 1 ]. Among such patients, children from …

Respiratory Syncytial Virus (RSV) Burden in Infants in the Kingdom of Saudi Arabia and the Impact of All-Infant RSV Protection: A Modeling Study

Respiratory syncytial virus (RSV) is responsible for various respiratory illnesses, particularly lower track respiratory disease (LRTD), and is the primary cause of bronchiolitis and pneumonia. While individuals of all ages can be infected, RSV …