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Critical Care
Published in: Critical Care 1/2011

Open Access 01-02-2011 | Poster presentation

Pattern of cytokines and chemokines in exhaled breath condensate is related to the characteristics of mechanical ventilation

Authors: I Van Walree, A Van Houte, G Rijkers, H Van Velzen-Blad, H Endeman

Published in: Critical Care | Special Issue 1/2011

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Excerpt

Ventilator-associated lung injury (VALI) is an inflammatory response of the lung caused by mechanical ventilation (MV) and is related to tidal volumes (TV), positive end-expiratory pressure (PEEP) and peak pressures (Ppeak) [1]. In experimental settings, VALI is characterized by a local inflammatory response measured in tissue or lavate. It is difficult to obtain this material in the critically ill [2]. Exhaled breath condensate (EBC) is obtained in patients on MV using an easy non-invasive technique. In this pilot study we examined the relation between levels of inflammatory proteins in EBC of patients on MV and characteristics of MV. …
Literature
1.
Frank JA, et al.: Pathogenetic significance of biological markers of ventilator-associated lung injury in experimental and clinical studies. Chest 2006, 130: 1906-1914. 10.1378/chest.130.6.1906PubMedCentralCrossRefPubMed
2.
Perkins GD, et al.: Safety and tolerability of nonbronchoscopic lavage in ARDS. Chest 2005, 127: 1358-1363. 10.1378/chest.127.4.1358CrossRefPubMed
Metadata
Title
Pattern of cytokines and chemokines in exhaled breath condensate is related to the characteristics of mechanical ventilation
Authors
I Van Walree
A Van Houte
G Rijkers
H Van Velzen-Blad
H Endeman
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9564

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