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Published in: Critical Care 1/2011

Open Access 01-02-2011 | Poster presentation

Increased levels of soluble triggering receptor expressed on myeloid cells sTREM1 in ICU patients with cardiovascular disease and associated organ dysfunction

Authors: S Dewan, A Varma, M Talegaonkar

Published in: Critical Care | Special Issue 1/2011

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Excerpt

sTREM1, a new receptor of the immunoglobulin superfamily, is expressed on neutrophils and monocytes/macrophages. It has been reported to be a useful marker in infectious inflammatory conditions such as sepsis, pneumonia and pancreatitis. Cardiovascular disease with shock and associated organ dysfunction in the form of acute kidney injury (AKI) and acute liver damage (LD) is a unique subset of disease conditions mediated by the inflammatory process and there may be a role of sTREM1 levels in assessing the severity of disease and prognostication of the patient. We hypothesized that the sTREM1 level may be increased in patients with cardiovascular disease and organ dysfunction and it can be used as a prognostic marker. …
Literature
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go back to reference Soluble TREM1 and the diagnosis of pneumonia N Engl J Med 2004, 350: 451-458. 10.1056/NEJMoa031544 Soluble TREM1 and the diagnosis of pneumonia N Engl J Med 2004, 350: 451-458. 10.1056/NEJMoa031544
2.
go back to reference Increase level of sTREM1in patients with acute pancreatitis Crit Care Med 2008, 36: 2048-2053. 10.1097/CCM.0b013e31817b8824 Increase level of sTREM1in patients with acute pancreatitis Crit Care Med 2008, 36: 2048-2053. 10.1097/CCM.0b013e31817b8824
Metadata
Title
Increased levels of soluble triggering receptor expressed on myeloid cells sTREM1 in ICU patients with cardiovascular disease and associated organ dysfunction
Authors
S Dewan
A Varma
M Talegaonkar
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9700

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