Skip to main content
Top
Published in: Rheumatology and Therapy 2/2018

Open Access 01-12-2018 | Original Research

Patients with Rheumatic Diseases do not have an Increased Risk of MRSA Carrier Status

Authors: Judith Krämer, Konstantinos Triantafyllias, Wolfgang Kohnen, Martin Leber, Ute Dederichs-Masius, Andrea Zucker, Jürgen Körber, Andreas Schwarting

Published in: Rheumatology and Therapy | Issue 2/2018

Login to get access

Abstract

Introduction

The aim of this study was to determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) both in rheumatologic and non-rheumatologic rehabilitation centers. In addition, we sought to evaluate the practice value of existing screening recommendations of the German Commission for Hospital Hygiene and Infection Prevention (KRINKO).

Methods

The analysis was performed in four rehabilitation clinics (rheumatology, psychosomatic medicine, oncology, and cardiology) with at least 200 patients per clinic tested for MRSA.

Results

Nine (1.1%) of the 842 patients were colonized with MRSA. Only five of them should have been tested according to the commission’s recommendations. The prevalence was 0.5% (n = 207) in rheumatologic, 0.9% (n = 224) in psychosomatic, 1.4% (n = 209) in oncologic and 1.5% (n = 202) in cardiologic patients. We found a greater exposure to risk factors in cardiologic and oncologic patients. Among patients with carrier status, a higher percentage was exposed to three potential risk factors not applied by the commission.

Conclusions

The prevalence of MRSA in our cohort correlates with data from previous studies. The low percentage among rheumatologic patients suggests that they are not more likely to reveal MRSA carrier status than other patient groups and that long-term immunosuppression does not necessarily represent a risk factor for MRSA colonization. Since only five out of nine patients with carrier status would have been detected following the recommendations of the KRINKO, further studies on potential risk factors are warranted.
Literature
2.
go back to reference Roth VR, Longpre T, Coyle D, Suh KN, Taljaard M, Muldoon KA, et al. Cost analysis of universal screening vs. risk factor-based screening for methicillin-resistant Staphylococcus aureus (MRSA). PLoS ONE. 2016;11(7):e159667.CrossRef Roth VR, Longpre T, Coyle D, Suh KN, Taljaard M, Muldoon KA, et al. Cost analysis of universal screening vs. risk factor-based screening for methicillin-resistant Staphylococcus aureus (MRSA). PLoS ONE. 2016;11(7):e159667.CrossRef
4.
go back to reference Empfehlungen zur Prävention und Kontrolle von Methicillin-resistenten Staphylococcus aureus-Stämmen (MRSA) in medizinischen und pflegerischen Einrichtungen; Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention (KRINKO) beim Robert Koch-Institut. [Recommendations for the prevention and control of methicillin-resistant Staphylococcus aureus strains (MRSA) in medical and nursing facilities; recommendations of the Commission for Hospital Hygiene and Infection Prevention (KRINKO) of the Robert-Koch-Institute.] Bundesgesundheitsblatt—Gesundheitsforschung—Gesundheitsschutz. 2014; 57:696–732. doi:10.1007/s00103-014-1980-x (in German). Empfehlungen zur Prävention und Kontrolle von Methicillin-resistenten Staphylococcus aureus-Stämmen (MRSA) in medizinischen und pflegerischen Einrichtungen; Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention (KRINKO) beim Robert Koch-Institut. [Recommendations for the prevention and control of methicillin-resistant Staphylococcus aureus strains (MRSA) in medical and nursing facilities; recommendations of the Commission for Hospital Hygiene and Infection Prevention (KRINKO) of the Robert-Koch-Institute.] Bundesgesundheitsblatt—Gesundheitsforschung—Gesundheitsschutz. 2014; 57:696–732. doi:10.1007/s00103-014-1980-x (in German).
8.
go back to reference Köck R, Winner K, Schaumburg F, Jurke A, Rossen JW, Friedrich AW. Admission prevalence and acquisition of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in German rehabilitation centres. J Hospital Infect. 2014;87(2):115–8. https://doi.org/10.1016/j.jhin.CrossRef Köck R, Winner K, Schaumburg F, Jurke A, Rossen JW, Friedrich AW. Admission prevalence and acquisition of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in German rehabilitation centres. J Hospital Infect. 2014;87(2):115–8. https://​doi.​org/​10.​1016/​j.​jhin.CrossRef
9.
go back to reference Varley CD, et al. Persistence of Staphylococcus aureus colonization among individuals with immune-mediated inflammatory diseases treated with TNF-α inhibitor therapy. Rheumatology. 2014;53(2):332–7.CrossRef Varley CD, et al. Persistence of Staphylococcus aureus colonization among individuals with immune-mediated inflammatory diseases treated with TNF-α inhibitor therapy. Rheumatology. 2014;53(2):332–7.CrossRef
10.
go back to reference Jain A, Agarwal A, Verma RK. Cefoxitin disc diffusion test for detection of methicillin-resistant staphylococci. J Med Microbiol. 2008;57(Pt 8):957–61.CrossRef Jain A, Agarwal A, Verma RK. Cefoxitin disc diffusion test for detection of methicillin-resistant staphylococci. J Med Microbiol. 2008;57(Pt 8):957–61.CrossRef
11.
go back to reference Bramble M, Morris D, Tolomeo P, Lautenbach E. Potential role of pet animals in household transmission of methicillin-resistant Staphylococcus aureus: a narrative review. Vector Borne Zoonotic Dis. 2011;11(6):617–20 Epub 2010 Dec 13.CrossRef Bramble M, Morris D, Tolomeo P, Lautenbach E. Potential role of pet animals in household transmission of methicillin-resistant Staphylococcus aureus: a narrative review. Vector Borne Zoonotic Dis. 2011;11(6):617–20 Epub 2010 Dec 13.CrossRef
12.
go back to reference Weese JS. Methicillin-resistant Staphylococcus aureus in animals. ILAR J. 2010;51(3):233–44.CrossRef Weese JS. Methicillin-resistant Staphylococcus aureus in animals. ILAR J. 2010;51(3):233–44.CrossRef
Metadata
Title
Patients with Rheumatic Diseases do not have an Increased Risk of MRSA Carrier Status
Authors
Judith Krämer
Konstantinos Triantafyllias
Wolfgang Kohnen
Martin Leber
Ute Dederichs-Masius
Andrea Zucker
Jürgen Körber
Andreas Schwarting
Publication date
01-12-2018
Publisher
Springer Healthcare
Published in
Rheumatology and Therapy / Issue 2/2018
Print ISSN: 2198-6576
Electronic ISSN: 2198-6584
DOI
https://doi.org/10.1007/s40744-018-0116-4

Other articles of this Issue 2/2018

Rheumatology and Therapy 2/2018 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.