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Published in: World Journal of Emergency Surgery 1/2014

Open Access 01-12-2014 | Research article

Patient delay is the main cause of treatment delay in acute limb ischemia: an investigation of pre- and in-hospital time delay

Authors: Louise S Londero, Birgitte Nørgaard, Kim Houlind

Published in: World Journal of Emergency Surgery | Issue 1/2014

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Abstract

Background

The prognosis of acute limb ischemia is severe, with amputation rates of up to 25% and in-hospital mortality of 9-15%. Delay in treatment increases the risk of major amputation and may be present at different stages, including patient delay, doctors´ delay and waiting time in the emergency department. It is important to identify existing problems in order to reduce time delay.
The aim of this study was to collect data for patients with acute limb ischemia and to evaluate the time delay between the different events from onset of symptoms to specialist evaluation and further treatment with focus on pre-hospital and in-hospital time delays.

Methods

We conducted a prospective cross-sectional cohort study including all patients suspected with acute limb ischemia who were admitted to the emergency department of a community hospital in a six months period. Temporal delay in the different phases between the time of occurrence of symptoms and completion of treatment was recorded prospectively. All patients who underwent intervention had a 30 days follow-up with regard to major amputation of the leg and survival.

Results

A total of 42 patients (21 men and 21 women) age 73 (20–95) years (median (range)) was identified.
From onset of symptoms to first contact with a doctor the time for all patients were 24 (0–1200) hours. Thirty patients needed immediate intervention. In the group of fourteen patients who had immediate operation, the median time from vascular evaluation to revascularization was 324.5 (122–873) minutes and in the group of eight patients that went through an imaging procedure before an operation the median delay was 822 (494–1185) minutes from specialist assessment to revascularization. The median time for revascularization among four patients, who were treated with arterial thrombolysis was 5621 (1686–8376) minutes.
At 30 days follow up, six patients had had the ischemic limb amputated above the ankle and four patients had died.

Conclusions

We found that the largest time delay was between onset of symptoms and first contact to a medical doctor. A greater public awareness is needed, so as to facilitate urgent revascularisation and improve outcomes.
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Literature
1.
go back to reference Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, Group TIW, Bell K, Caporusso J, Durand-Zaleski I, Komori K, Lammer J, Liapis C, Novo S, Razavi M, Robbs J, Schaper N, Shigematsu H, Sapoval M, White C, White J, Clement D, Creager M, Jaff M, Mohler E, Rutherford RB, Sheehan P, Sillesen H, Rosenfield K: Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). Eur J Vasc Endovasc Surg: Off J Eur J Vasc Endovasc Surg. 2007, 33 (Suppl 1): S1-75.CrossRef Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, Group TIW, Bell K, Caporusso J, Durand-Zaleski I, Komori K, Lammer J, Liapis C, Novo S, Razavi M, Robbs J, Schaper N, Shigematsu H, Sapoval M, White C, White J, Clement D, Creager M, Jaff M, Mohler E, Rutherford RB, Sheehan P, Sillesen H, Rosenfield K: Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). Eur J Vasc Endovasc Surg: Off J Eur J Vasc Endovasc Surg. 2007, 33 (Suppl 1): S1-75.CrossRef
2.
go back to reference Eliason JL, Wainess RM, Proctor MC, Dimick JB, Cowan JA, Upchurch GR, Stanley JC, Henke PK: A national and single institutional experience in the contemporary treatment of acute lower extremity ischemia. AnnSurg. 2003, 238 (3): 382-389. Eliason JL, Wainess RM, Proctor MC, Dimick JB, Cowan JA, Upchurch GR, Stanley JC, Henke PK: A national and single institutional experience in the contemporary treatment of acute lower extremity ischemia. AnnSurg. 2003, 238 (3): 382-389.
3.
go back to reference Ouriel K, Veith FJ: Acute lower limb ischemia: determinants of outcome. Surgery. 1998, 124 (2): 336-341. 10.1016/S0039-6060(98)70139-4.CrossRefPubMed Ouriel K, Veith FJ: Acute lower limb ischemia: determinants of outcome. Surgery. 1998, 124 (2): 336-341. 10.1016/S0039-6060(98)70139-4.CrossRefPubMed
4.
go back to reference Rutherford RB, Baker JD, Ernst C, Johnston KW, Porter JM, Ahn S, Jones DN: Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg. 1997, 26 (3): 517-538. 10.1016/S0741-5214(97)70045-4.CrossRefPubMed Rutherford RB, Baker JD, Ernst C, Johnston KW, Porter JM, Ahn S, Jones DN: Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg. 1997, 26 (3): 517-538. 10.1016/S0741-5214(97)70045-4.CrossRefPubMed
5.
go back to reference Campbell WB, Ridler BM, Szymanska TH: Current management of acute leg ischaemia: results of an audit by the Vascular Surgical Society of Great Britain and Ireland. British J Surg. 1998, 85 (11): 1498-1503. 10.1046/j.1365-2168.1998.00906.x.CrossRef Campbell WB, Ridler BM, Szymanska TH: Current management of acute leg ischaemia: results of an audit by the Vascular Surgical Society of Great Britain and Ireland. British J Surg. 1998, 85 (11): 1498-1503. 10.1046/j.1365-2168.1998.00906.x.CrossRef
6.
go back to reference Karapolat S, Dag O, Abanoz M, Aslan M: Arterial embolectomy: a retrospective evaluation of 730 cases over 20 years. Surg Today. 2006, 36 (5): 416-419. 10.1007/s00595-005-3156-7.CrossRefPubMed Karapolat S, Dag O, Abanoz M, Aslan M: Arterial embolectomy: a retrospective evaluation of 730 cases over 20 years. Surg Today. 2006, 36 (5): 416-419. 10.1007/s00595-005-3156-7.CrossRefPubMed
7.
go back to reference Burgess NA, Scriven MW, Lewis MH: An 11-year experience of arterial embolectomy in a district general hospital. J R Coll Surg Edinb. 1994, 39 (2): 93-96.PubMed Burgess NA, Scriven MW, Lewis MH: An 11-year experience of arterial embolectomy in a district general hospital. J R Coll Surg Edinb. 1994, 39 (2): 93-96.PubMed
8.
go back to reference Ieraci S, Digiusto E, Sonntag P, Dann L, Fox D: Streaming by case complexity: evaluation of a model for emergency department Fast Track. Emerg Med Australas. 2008, 20 (3): 241-249. 10.1111/j.1742-6723.2008.01087.x.CrossRefPubMed Ieraci S, Digiusto E, Sonntag P, Dann L, Fox D: Streaming by case complexity: evaluation of a model for emergency department Fast Track. Emerg Med Australas. 2008, 20 (3): 241-249. 10.1111/j.1742-6723.2008.01087.x.CrossRefPubMed
9.
go back to reference Nash K, Zachariah B, Nitschmann J, Psencik B: Evaluation of the fast track unit of a university emergency department. J Emerg Nurs. 2007, 33 (1): 14-20. 10.1016/j.jen.2006.08.003.CrossRefPubMed Nash K, Zachariah B, Nitschmann J, Psencik B: Evaluation of the fast track unit of a university emergency department. J Emerg Nurs. 2007, 33 (1): 14-20. 10.1016/j.jen.2006.08.003.CrossRefPubMed
10.
go back to reference Sanchez M, Smally AJ, Grant RJ, Jacobs LM: Effects of a fast-track area on emergency department performance. J Emerg Med. 2006, 31 (1): 117-120. 10.1016/j.jemermed.2005.08.019.CrossRefPubMed Sanchez M, Smally AJ, Grant RJ, Jacobs LM: Effects of a fast-track area on emergency department performance. J Emerg Med. 2006, 31 (1): 117-120. 10.1016/j.jemermed.2005.08.019.CrossRefPubMed
15.
go back to reference Kuukasjarvi P, Salenius JP: Perioperative outcome of acute lower limb ischaemia on the basis of the national vascular registry. Finnvasc Study Group Eur J Vasc Surg. 1994, 8 (5): 578-583. 10.1016/S0950-821X(05)80594-8.CrossRef Kuukasjarvi P, Salenius JP: Perioperative outcome of acute lower limb ischaemia on the basis of the national vascular registry. Finnvasc Study Group Eur J Vasc Surg. 1994, 8 (5): 578-583. 10.1016/S0950-821X(05)80594-8.CrossRef
16.
go back to reference Morris-Stiff G, D'Souza J, Raman S, Paulvannan S, Lewis MH: Update experience of surgery for acute limb ischaemia in a district general hospital - are we getting any better?. Ann R Coll Surg Engl. 2009, 91 (8): 637-640. 10.1308/003588409X12486167521271.PubMedCentralCrossRefPubMed Morris-Stiff G, D'Souza J, Raman S, Paulvannan S, Lewis MH: Update experience of surgery for acute limb ischaemia in a district general hospital - are we getting any better?. Ann R Coll Surg Engl. 2009, 91 (8): 637-640. 10.1308/003588409X12486167521271.PubMedCentralCrossRefPubMed
Metadata
Title
Patient delay is the main cause of treatment delay in acute limb ischemia: an investigation of pre- and in-hospital time delay
Authors
Louise S Londero
Birgitte Nørgaard
Kim Houlind
Publication date
01-12-2014
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2014
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/1749-7922-9-56

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