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Immunity & Ageing
Published in: Immunity & Ageing 1/2009

Open Access 01-12-2009 | Review

Pathophysiology of vascular dementia

Authors: Francesco Iemolo, Giovanni Duro, Claudia Rizzo, Laura Castiglia, Vladimir Hachinski, Calogero Caruso

Published in: Immunity & Ageing | Issue 1/2009

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Abstract

The concept of Vascular Dementia (VaD) has been recognized for over a century, but its definition and diagnostic criteria remain unclear.
Conventional definitions identify the patients too late, miss subjects with cognitive impairment short of dementia, and emphasize consequences rather than causes, the true bases for treatment and prevention. We should throw out current diagnostic categories and describe cognitive impairment clinically and according to commonly agreed instruments that document the demographic data in a standardized manner and undertake a systematic effort to identify the underlying aetiology in each case.
Increased effort should be targeted towards the concept of and criteria for Vascular Cognitive Impairment and Post-Stroke Dementia as well as for genetic factors involved, especially as these categories hold promise for early prevention and treatment.
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Metadata
Title
Pathophysiology of vascular dementia
Authors
Francesco Iemolo
Giovanni Duro
Claudia Rizzo
Laura Castiglia
Vladimir Hachinski
Calogero Caruso
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Immunity & Ageing / Issue 1/2009
Electronic ISSN: 1742-4933
DOI
https://doi.org/10.1186/1742-4933-6-13

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