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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

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Open Access 01-12-2021 | Parkinson's Disease | Review

Clinical features contributing to the sit-to-stand transfer in people with Parkinson’s disease: a systematic review

Authors: Charmaine Pearl Da Cunha, Pratiksha Tilak Rao, Suruliraj Karthikbabu

Published in: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery | Issue 1/2021

Abstract

Introduction

The aim of this systematic review is to present the existing literature on the clinical motor, and non-motor factors contributing to sit-to-stand transfer in individuals with Parkinson's disease.

Data synthesis

Five databases (PubMed, PEDro, Cochrane, SCOPUS, and Ovid) were searched for literature on the contributing factors to sit-to-stand performance in Parkinson's disease. A quality check of these observational studies was done using the 'strengthening the reporting of observational studies in epidemiology' (STROBE) statement and the tool of the 'National Heart, Lung, and Blood Institute' (NHLBI). Descriptive and quantitative data were extracted and compiled, and a meta-analysis was performed to compute the standardised mean difference.

Results

Thirteen studies were selected; a majority of them provided a high-to-moderate level of evidence. Ten were cross-sectional, while the other three were case–control studies. Collectively, individuals with Parkinson's disease had a prolonged transfer time than those of age-matched healthy peers, particularly from peak horizontal velocity phase to seat-off phase, implying bradykinesia. A reduction in peak and rate to peak joint torques was also related to the decreased pace and stability of the sit-to-stand movement in individuals with Parkinson's disease. Additionally, they demonstrated exaggerated trunk flexion as a postural stabilisation strategy, allowing them to maintain and manoeuvre the relative positions of their centre of mass through the transitional phase of the transfer.

Conclusion

As per the existing literature, an alteration in strength, overall body bradykinesia, balance, posture, as well as cognition may result in an impaired sit-to-stand transfer in individuals with Parkinson's disease.

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Title: Clinical features contributing to the sit-to-stand transfer in people with Parkinson’s disease: a systematic review
Authors: Charmaine Pearl Da Cunha
Pratiksha Tilak Rao
Suruliraj Karthikbabu
Publication date: 01-12-2021
Publisher: Springer Berlin Heidelberg
Keyword: Parkinson's Disease
Published in: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery / Issue 1/2021
Electronic ISSN: 1687-8329
DOI: https://doi.org/10.1186/s41983-021-00396-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical features contributing to the sit-to-stand transfer in people with Parkinson’s disease: a systematic review

Abstract

Introduction

Data synthesis

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Data synthesis

Results

Conclusion

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