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Published in: World Journal of Surgical Oncology 1/2011

Open Access 01-12-2011 | Case report

Parathyroid autotransplantation in extensive head and neck resections: case series report

Authors: Panagiotis G Athanasopoulos, Maria Kyriazi, Nikolaos Arkadopoulos, Dionysios Dellaportas, Asimina Manta, Theodosios Theodosopoulos, Aliki Tympa, Ioannis Vassileiou, Vassilios Smyrniotis

Published in: World Journal of Surgical Oncology | Issue 1/2011

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Abstract

Permanent or temporary hypoparathyroidism may be a debilitating result of radical cervical surgery, as noted most commonly following thyroid or parathyroid surgery. However, it can also be the outcome of any surgical procedure involving bilateral extensive manipulation of the anterior neck triangle, especially in order to ensure oncologically adequate surgical margins.
We report our experience of three patients that underwent parathyroid immediate autotransplanation following extensive surgical manipulations of the neck region for oncological reasons. PTH levels were restored to normal by the fourth postoperative week, allowing us to wean the patients off calcium and vitamin D3 supplementation, which was attributed to full autograft function. Parathyroid autotransplantation, immediate or delayed, is a simple and safe technique which should be considered by the surgeon whenever there is a high risk for postoperative hypoparathyroidism following radical operations of the neck for oncological reasons.
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Literature
1.
2.
3.
go back to reference Muller JM, Erasmi H, Stelzner M, Zieren U, Pichlmaier H: Surgical therapy of oesophageal carcinoma. Br J Surg. 1990, 77: 845-57. 10.1002/bjs.1800770804.CrossRefPubMed Muller JM, Erasmi H, Stelzner M, Zieren U, Pichlmaier H: Surgical therapy of oesophageal carcinoma. Br J Surg. 1990, 77: 845-57. 10.1002/bjs.1800770804.CrossRefPubMed
5.
go back to reference Lahey FH: The transplantation of parathyroids in partial thyroidectomy. Surg Gynecol Obstet. 1926, 62: 508-9. Lahey FH: The transplantation of parathyroids in partial thyroidectomy. Surg Gynecol Obstet. 1926, 62: 508-9.
6.
go back to reference Feldman AL, Sharaf RN, Skarulis MC, Bartlett DL, Libutti SK, Weinstein LS, Marx SJ, Norton JA, Fraker DL, Alexander HR: Results of heterotopic parathyroid autotransplantation: a 13-year experience. Surgery. 1999, 126: 1042-8. 10.1067/msy.2099.101580.CrossRefPubMed Feldman AL, Sharaf RN, Skarulis MC, Bartlett DL, Libutti SK, Weinstein LS, Marx SJ, Norton JA, Fraker DL, Alexander HR: Results of heterotopic parathyroid autotransplantation: a 13-year experience. Surgery. 1999, 126: 1042-8. 10.1067/msy.2099.101580.CrossRefPubMed
7.
go back to reference Niederle B, Roka R, Brennan MF: The transplantation of parathyroid tissue in man: development, indications, technique, and results. Endocr Rev. 1982, 3: 245-79. 10.1210/edrv-3-3-245.CrossRefPubMed Niederle B, Roka R, Brennan MF: The transplantation of parathyroid tissue in man: development, indications, technique, and results. Endocr Rev. 1982, 3: 245-79. 10.1210/edrv-3-3-245.CrossRefPubMed
8.
go back to reference Baumann DS, Wells SA: Parathyroid autotransplantation. Surgery. 1993, 113: 130-3.PubMed Baumann DS, Wells SA: Parathyroid autotransplantation. Surgery. 1993, 113: 130-3.PubMed
9.
go back to reference Carter WB, Uy K, Ward MD, Hoying JB: Parathyroid-induced angiogenesis is VEGF-dependent. Surgery. 2000, 128: 458-64. 10.1067/msy.2000.107102.CrossRefPubMed Carter WB, Uy K, Ward MD, Hoying JB: Parathyroid-induced angiogenesis is VEGF-dependent. Surgery. 2000, 128: 458-64. 10.1067/msy.2000.107102.CrossRefPubMed
10.
go back to reference Wells SA, Farndon JR, Dale JK, Leight GS, Dilley WG: Long-term evaluation of patients with primary parathyroid hyperplasia managed by total parathyroidectomy and heterotopic autotransplantation. Ann Surg. 1980, 192: 451-8. 10.1097/00000658-198010000-00003.PubMedCentralCrossRefPubMed Wells SA, Farndon JR, Dale JK, Leight GS, Dilley WG: Long-term evaluation of patients with primary parathyroid hyperplasia managed by total parathyroidectomy and heterotopic autotransplantation. Ann Surg. 1980, 192: 451-8. 10.1097/00000658-198010000-00003.PubMedCentralCrossRefPubMed
11.
go back to reference Borot S, Lapierre V, Carnaille B, Goudet P, Penfornis A: Results of cryopreserved parathyroid autografts: a retrospective multicenter study. Surgery. 2010, 147: 529-35. 10.1016/j.surg.2009.10.010.CrossRefPubMed Borot S, Lapierre V, Carnaille B, Goudet P, Penfornis A: Results of cryopreserved parathyroid autografts: a retrospective multicenter study. Surgery. 2010, 147: 529-35. 10.1016/j.surg.2009.10.010.CrossRefPubMed
12.
go back to reference Olson JA, DeBenedetti MK, Baumann DS, Wells SA: Parathyroid autotransplantation during thyroidectomy: Results of long-term follow-up. Ann Surg. 1996, 223: 472-8. 10.1097/00000658-199605000-00003. discussion 478-80PubMedCentralCrossRefPubMed Olson JA, DeBenedetti MK, Baumann DS, Wells SA: Parathyroid autotransplantation during thyroidectomy: Results of long-term follow-up. Ann Surg. 1996, 223: 472-8. 10.1097/00000658-199605000-00003. discussion 478-80PubMedCentralCrossRefPubMed
Metadata
Title
Parathyroid autotransplantation in extensive head and neck resections: case series report
Authors
Panagiotis G Athanasopoulos
Maria Kyriazi
Nikolaos Arkadopoulos
Dionysios Dellaportas
Asimina Manta
Theodosios Theodosopoulos
Aliki Tympa
Ioannis Vassileiou
Vassilios Smyrniotis
Publication date
01-12-2011
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2011
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-9-149

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