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International Urology and Nephrology
Published in: International Urology and Nephrology 5/2013

01-10-2013 | Nephrology – Case Report

Paradoxical cryptococcal immune reconstitution inflammatory syndrome in advanced chronic kidney disease

Authors: Chih-Chin Kao, Vin-Cent Wu, Hsin-Yun Sun, Che-Hsiung Wu, The NSARF Group

Published in: International Urology and Nephrology | Issue 5/2013

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Abstract

Cryptococcal-related immune reconstitution inflammatory syndrome (IRIS) is frequently seen in immunocompromised patients. A 45-year-old man with advanced chronic kidney disease (CKD) received intensive antifungal treatment for pulmonary cryptococcosis. Despite negative pleural effusion cultures and declining serum cryptococcal antigen titers, the patient presented with progressive pulmonary infiltration, intermittent fever, and elevated C-reactive protein. Steroids were given for suspected IRIS, and the clinical condition improved dramatically. This is the first report on paradoxical cryptococcal IRIS in a patient with advanced CKD.
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Metadata
Title
Paradoxical cryptococcal immune reconstitution inflammatory syndrome in advanced chronic kidney disease
Authors
Chih-Chin Kao
Vin-Cent Wu
Hsin-Yun Sun
Che-Hsiung Wu
The NSARF Group
Publication date
01-10-2013
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 5/2013
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-012-0196-y

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