Published in:
01-11-2020 | Panniculitis | Case Report
Concomitant calciphylaxis and COVID-19 associated thrombotic retiform purpura
Authors:
Jessica A. Rotman, Kathryn E. Dean, Cynthia Magro, Gerard Nuovo, Roger J. Bartolotta
Published in:
Skeletal Radiology
|
Issue 11/2020
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Abstract
While initial reports regarding coronavirus disease 2019 (COVID-19) focused on its pulmonary manifestations, more recent literature describes multisystem abnormalities related to its associated microvascular angiopathy. Calciphylaxis is a rare systemic condition characterized by tissue necrosis in the setting of systemic microvascular calcifications. Both COVID-19 and calciphylaxis are procoagulant diagnoses associated with vascular-mediated cutaneous findings. To our knowledge, this is the first report to document the coexistence of COVID-19 associated retiform thrombotic purpura and calciphylaxis in a single patient, to link the pathologic etiologies of the two entities, and to describe the concomitant diagnoses’ associated radiologic findings.