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01-09-2020 | Pancreatectomy | Original Article

Distal pancreatectomy with en bloc celiac axis resection for pancreatic cancer: a pooled analysis of 109 cases

Authors: Jianfa Lan, Yufeng Chen, Shijie Wang, Yanming Zhou

Published in: Updates in Surgery | Issue 3/2020

Abstract

The aim of this study was to define the clinical outcome and prognostic determinants of distal pancreatectomy with en bloc celiac axis resection (DP-CAR) for pancreatic body/tail cancer. A pooled data analysis was performed on individual data for patients who underwent DP-CAR for pancreatic body/tail cancer as identified by systematic literature search. A total of 32 articles involving 109 patients were eligible for inclusion. Postoperative morbidity and mortality were 53% and 4%, respectively. Preoperative abdominal and/or back pain was completely relieved immediately after surgery in 98% of patients. The 1, 3 and 5 years overall survival (OS) rates were 59%, 21% and 10%, and the median OS was 14 months. Patients who received neoadjuvant treatment had a median OS of 23 months. In conclusion, DP-CAR for locally advanced pancreatic body/tail cancer can be performed safely with low mortality and provides survival benefit when combined with neoadjuvant treatment.

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Title: Distal pancreatectomy with en bloc celiac axis resection for pancreatic cancer: a pooled analysis of 109 cases
Authors: Jianfa Lan
Yufeng Chen
Shijie Wang
Yanming Zhou
Publication date: 01-09-2020
Publisher: Springer International Publishing
Keywords: Pancreatectomy
Arterial Reconstruction
Pancreatic Cancer
Pancreatic Cancer
Published in: Updates in Surgery / Issue 3/2020
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI: https://doi.org/10.1007/s13304-020-00826-2

At a glance: The STEP trials

Springer Medicine

Distal pancreatectomy with en bloc celiac axis resection for pancreatic cancer: a pooled analysis of 109 cases

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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