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Published in: BMC Musculoskeletal Disorders 1/2021

Open Access 01-12-2021 | Painful Arc | Research article

Retear rates after rotator cuff surgery: a systematic review and meta-analysis

Authors: Umile Giuseppe Longo, Arianna Carnevale, Ilaria Piergentili, Alessandra Berton, Vincenzo Candela, Emiliano Schena, Vincenzo Denaro

Published in: BMC Musculoskeletal Disorders | Issue 1/2021

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Abstract

Background

Rotator cuff retear (RCR) is one of the main postoperative drawbacks. RCR can be considered a multifactorial issue, which causes are related either to biological than biomechanical factors. The aim of this study was to define the incidence of RCR after surgical treatment at different time points and to identify the main factors influencing the postoperative rotator cuff (RC) healing.

Methods

A systematic review and meta-analysis were performed following the PRISMA guidelines. A comprehensive search of the literature was carried out in July 2020, using PubMed and Cochrane Library databases. Only level 1 and 2 clinical evidence studies were included. Studies were included if patients with preoperative repairable full-thickness RC tears were treated surgically, and if studies reported postoperative RCR confirmed by imaging diagnostic. The association between timing of retear and follow-up time points were investigated using an inverse-variance method of pooling data. A subgroup meta-analysis was performed using the DerSimonian and Laird method for the estimation of the between-study variance, i.e., τ2. The association between retear rate after surgery and patients’ age, preoperative tear size, fatty infiltration, postoperative rehabilitation protocol, surgical techniques, and RC repairs was determined by expressing the effect measure in terms of odds ratio (OR) with 95% confidence interval (CI). The Mantel-Haenszel method with 95% CIs was used.

Results

Thirty-one articles were included in this study. The percentage of RCR after surgery was 15% at 3 months follow-up, 21% at 3–6 months follow-up, 16% at 6–12 months follow-up, 21% at 12–24 months follow-up, 16% at follow-up longer than 24 months. The main factors influencing RC healing are both patient-related (i.e., age, larger tear size, fatty infiltration) and not patient-related (i.e., postoperative rehabilitation protocol, surgical techniques, and procedures).

Conclusions

Postoperative RC healing is influenced by patient-related and non-patient-related factors. Further high-level clinical studies are needed to provide highly relevant clinical results.
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Literature
1.
go back to reference Longo UG, Ambrogioni LR, Berton A, Candela V, Carnevale A, Schena E, et al. Physical therapy and precision rehabilitation in shoulder rotator cuff disease. Int Orthop. 2020:1–11. Longo UG, Ambrogioni LR, Berton A, Candela V, Carnevale A, Schena E, et al. Physical therapy and precision rehabilitation in shoulder rotator cuff disease. Int Orthop. 2020:1–11.
7.
go back to reference Iijima Y, Matsuki K, Hoshika S, Ueda Y, Hamada H, Tokai M, Takahashi N, Sugaya H, Watanabe A. Relationship between postoperative retear and preoperative fatty degeneration in large and massive rotator cuff tears: quantitative analysis using T2 mapping. J Shoulder Elbow Surg. 2019;28(8):1562–67. https://doi.org/10.1016/j.jse.2019.04.036. Iijima Y, Matsuki K, Hoshika S, Ueda Y, Hamada H, Tokai M, Takahashi N, Sugaya H, Watanabe A. Relationship between postoperative retear and preoperative fatty degeneration in large and massive rotator cuff tears: quantitative analysis using T2 mapping. J Shoulder Elbow Surg. 2019;28(8):1562–67. https://​doi.​org/​10.​1016/​j.​jse.​2019.​04.​036.
12.
go back to reference Gartsman GM, Drake G, Edwards TB, Elkousy HA, Hammerman SM, O'Connor DP, et al. Ultrasound evaluation of arthroscopic full-thickness supraspinatus rotator cuff repair: single-row versus double-row suture bridge (transosseous equivalent) fixation. Results of a prospective, randomized study. J Shoulder Elb Surg. 2013;22(11):1480–7. https://doi.org/10.1016/j.jse.2013.06.020.CrossRef Gartsman GM, Drake G, Edwards TB, Elkousy HA, Hammerman SM, O'Connor DP, et al. Ultrasound evaluation of arthroscopic full-thickness supraspinatus rotator cuff repair: single-row versus double-row suture bridge (transosseous equivalent) fixation. Results of a prospective, randomized study. J Shoulder Elb Surg. 2013;22(11):1480–7. https://​doi.​org/​10.​1016/​j.​jse.​2013.​06.​020.CrossRef
14.
go back to reference Nazari G, MacDermid JC, Bryant D, Dewan N, Athwal GS. Effects of arthroscopic vs. mini-open rotator cuff repair on function, pain & range of motion. A systematic review and meta-analysis. PLoS One. 2019;14(10):e0222953.CrossRefPubMedPubMedCentral Nazari G, MacDermid JC, Bryant D, Dewan N, Athwal GS. Effects of arthroscopic vs. mini-open rotator cuff repair on function, pain & range of motion. A systematic review and meta-analysis. PLoS One. 2019;14(10):e0222953.CrossRefPubMedPubMedCentral
16.
go back to reference Hein J, Reilly JM, Chae J, Maerz T, Anderson K. Retear rates after arthroscopic single-row, double-row, and suture bridge rotator Cuff repair at a minimum of 1 year of imaging follow-up: a systematic review. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2015;31(11):2274–81. https://doi.org/10.1016/j.arthro.2015.06.004.CrossRef Hein J, Reilly JM, Chae J, Maerz T, Anderson K. Retear rates after arthroscopic single-row, double-row, and suture bridge rotator Cuff repair at a minimum of 1 year of imaging follow-up: a systematic review. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2015;31(11):2274–81. https://​doi.​org/​10.​1016/​j.​arthro.​2015.​06.​004.CrossRef
22.
go back to reference Longo UG, Rizzello G, Petrillo S, Loppini M, Maffulli N, Denaro V. Conservative Rehabilitation Provides Superior Clinical Results Compared to Early Aggressive Rehabilitation for Rotator Cuff Repair: A Retrospective Comparative Study. Medicina (Kaunas). 2019;55(8):402. https://doi.org/10.3390/medicina55080402. Longo UG, Rizzello G, Petrillo S, Loppini M, Maffulli N, Denaro V. Conservative Rehabilitation Provides Superior Clinical Results Compared to Early Aggressive Rehabilitation for Rotator Cuff Repair: A Retrospective Comparative Study. Medicina (Kaunas). 2019;55(8):402. https://​doi.​org/​10.​3390/​medicina55080402​.
31.
go back to reference Cumpston M, Li T, Page MJ, Chandler J, Welch VA, Higgins JP, et al. Updated guidance for trusted systematic reviews: a new edition of the Cochrane handbook for systematic reviews of interventions. Cochrane Database Syst Rev. 2019;10:ED000142.PubMed Cumpston M, Li T, Page MJ, Chandler J, Welch VA, Higgins JP, et al. Updated guidance for trusted systematic reviews: a new edition of the Cochrane handbook for systematic reviews of interventions. Cochrane Database Syst Rev. 2019;10:ED000142.PubMed
32.
go back to reference Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;350:g7647.CrossRefPubMed Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;350:g7647.CrossRefPubMed
47.
go back to reference Malavolta EA, Gracitelli MEC, Assunção JH, Ferreira Neto AA, Bordalo-Rodrigues M, de Camargo OP. Clinical and structural evaluations of rotator Cuff repair with and without added platelet-rich plasma at 5-year follow-up: a prospective randomized study. Am J Sports Med. 2018;46(13):3134–41. https://doi.org/10.1177/0363546518795895.CrossRefPubMed Malavolta EA, Gracitelli MEC, Assunção JH, Ferreira Neto AA, Bordalo-Rodrigues M, de Camargo OP. Clinical and structural evaluations of rotator Cuff repair with and without added platelet-rich plasma at 5-year follow-up: a prospective randomized study. Am J Sports Med. 2018;46(13):3134–41. https://​doi.​org/​10.​1177/​0363546518795895​.CrossRefPubMed
48.
go back to reference Pandey V, Bandi A, Madi S, Agarwal L, Acharya KK, Maddukuri S, et al. Does application of moderately concentrated platelet-rich plasma improve clinical and structural outcome after arthroscopic repair of medium-sized to large rotator cuff tear? A randomized controlled trial. J Shoulder Elb Surg. 2016;25(8):1312–22. https://doi.org/10.1016/j.jse.2016.01.036.CrossRef Pandey V, Bandi A, Madi S, Agarwal L, Acharya KK, Maddukuri S, et al. Does application of moderately concentrated platelet-rich plasma improve clinical and structural outcome after arthroscopic repair of medium-sized to large rotator cuff tear? A randomized controlled trial. J Shoulder Elb Surg. 2016;25(8):1312–22. https://​doi.​org/​10.​1016/​j.​jse.​2016.​01.​036.CrossRef
52.
go back to reference Ruiz-Moneo P, Molano-Munoz J, Prieto E, Algorta J. Plasma rich in growth factors in arthroscopic rotator cuff repair: a randomized, double-blind, controlled clinical trial. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2013;29(1):2–9. https://doi.org/10.1016/j.arthro.2012.08.014.CrossRef Ruiz-Moneo P, Molano-Munoz J, Prieto E, Algorta J. Plasma rich in growth factors in arthroscopic rotator cuff repair: a randomized, double-blind, controlled clinical trial. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2013;29(1):2–9. https://​doi.​org/​10.​1016/​j.​arthro.​2012.​08.​014.CrossRef
57.
60.
go back to reference Greiner S, Ide J, Van Noort A, Mochizuki Y, Ochi H, Marraffino S, et al. Local rhBMP-12 on an absorbable collagen sponge as an adjuvant therapy for rotator Cuff repair - a phase 1, randomized, standard of care control, multicenter study: safety and feasibility. Am J Sports Med. 2015;43(8):1994–2004. https://doi.org/10.1177/0363546515584756.CrossRefPubMed Greiner S, Ide J, Van Noort A, Mochizuki Y, Ochi H, Marraffino S, et al. Local rhBMP-12 on an absorbable collagen sponge as an adjuvant therapy for rotator Cuff repair - a phase 1, randomized, standard of care control, multicenter study: safety and feasibility. Am J Sports Med. 2015;43(8):1994–2004. https://​doi.​org/​10.​1177/​0363546515584756​.CrossRefPubMed
63.
go back to reference Ide J, Mochizuki Y, van Noort A, Ochi H, Sridharan S, Itoi E, et al. Local rhBMP-12 on an absorbable collagen sponge as an adjuvant therapy for rotator Cuff repair-a phase 1, randomized, standard of care control, multicenter study: part 2-a pilot study of functional recovery and structural outcomes. Orthop J Sports Med. 2017;5(9):2325967117726740. https://doi.org/10.1177/2325967117726740.CrossRefPubMedCentralPubMed Ide J, Mochizuki Y, van Noort A, Ochi H, Sridharan S, Itoi E, et al. Local rhBMP-12 on an absorbable collagen sponge as an adjuvant therapy for rotator Cuff repair-a phase 1, randomized, standard of care control, multicenter study: part 2-a pilot study of functional recovery and structural outcomes. Orthop J Sports Med. 2017;5(9):2325967117726740. https://​doi.​org/​10.​1177/​2325967117726740​.CrossRefPubMedCentralPubMed
68.
go back to reference Lee BG, Cho NS, Rhee YG. Effect of two rehabilitation protocols on range of motion and healing rates after arthroscopic rotator cuff repair: aggressive versus limited early passive exercises. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2012;28(1):34–42. https://doi.org/10.1016/j.arthro.2011.07.012.CrossRef Lee BG, Cho NS, Rhee YG. Effect of two rehabilitation protocols on range of motion and healing rates after arthroscopic rotator cuff repair: aggressive versus limited early passive exercises. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2012;28(1):34–42. https://​doi.​org/​10.​1016/​j.​arthro.​2011.​07.​012.CrossRef
70.
go back to reference Sheps DM, Silveira A, Beaupre L, Styles-Tripp F, Balyk R, Lalani A, et al. Early Active Motion Versus Sling Immobilization After Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial. Arthroscopy. 2019;35(3):749–760.e742.CrossRefPubMed Sheps DM, Silveira A, Beaupre L, Styles-Tripp F, Balyk R, Lalani A, et al. Early Active Motion Versus Sling Immobilization After Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial. Arthroscopy. 2019;35(3):749–760.e742.CrossRefPubMed
73.
go back to reference Bidwai AS, Birch A, Temperley D, Odak S, Walton MJ, Haines JF, et al. Medium- to long-term results of a randomized controlled trial to assess the efficacy of arthoscopic-subacromial decompression versus mini-open repair for the treatment of medium-sized rotator cuff tears. Shoulder Elbow. 2016;8(2):101–5. https://doi.org/10.1177/1758573215620571.CrossRefPubMed Bidwai AS, Birch A, Temperley D, Odak S, Walton MJ, Haines JF, et al. Medium- to long-term results of a randomized controlled trial to assess the efficacy of arthoscopic-subacromial decompression versus mini-open repair for the treatment of medium-sized rotator cuff tears. Shoulder Elbow. 2016;8(2):101–5. https://​doi.​org/​10.​1177/​1758573215620571​.CrossRefPubMed
75.
go back to reference Boehm TD, Werner A, Radtke S, Mueller T, Kirschner S, Gohlke F. The effect of suture materials and techniques on the outcome of repair of the rotator cuff: a prospective, randomised study. J Bone Joint Surg Br. 2005;87(6):819–23.CrossRefPubMed Boehm TD, Werner A, Radtke S, Mueller T, Kirschner S, Gohlke F. The effect of suture materials and techniques on the outcome of repair of the rotator cuff: a prospective, randomised study. J Bone Joint Surg Br. 2005;87(6):819–23.CrossRefPubMed
82.
go back to reference Antuna S, Barco R, Martinez Diez JM, Sanchez Marquez JM. Platelet-rich fibrin in arthroscopic repair of massive rotator cuff tears: a prospective randomized pilot clinical trial. Acta Orthop Belg. 2013;79(1):25–30.PubMed Antuna S, Barco R, Martinez Diez JM, Sanchez Marquez JM. Platelet-rich fibrin in arthroscopic repair of massive rotator cuff tears: a prospective randomized pilot clinical trial. Acta Orthop Belg. 2013;79(1):25–30.PubMed
84.
go back to reference De Roo PJ, Muermans S, Maroy M, Linden P, Van den Daelen L. Passive mobilization after arthroscopic rotator cuff repair is not detrimental in the early postoperative period. Acta Orthop Belg. 2015;81(3):485–92.PubMed De Roo PJ, Muermans S, Maroy M, Linden P, Van den Daelen L. Passive mobilization after arthroscopic rotator cuff repair is not detrimental in the early postoperative period. Acta Orthop Belg. 2015;81(3):485–92.PubMed
94.
go back to reference Longo UG, Berton A, Risi Ambrogioni L, Lo Presti D, Carnevale A, Candela V, Stelitano G, Schena E, Nazarian A, Denaro V. Cost-Effectiveness of Supervised versus Unsupervised Rehabilitation for Rotator-Cuff Repair: Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2020;17(8):2852. https://doi.org/10.3390/ijerph17082852. Longo UG, Berton A, Risi Ambrogioni L, Lo Presti D, Carnevale A, Candela V, Stelitano G, Schena E, Nazarian A, Denaro V. Cost-Effectiveness of Supervised versus Unsupervised Rehabilitation for Rotator-Cuff Repair: Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2020;17(8):2852. https://​doi.​org/​10.​3390/​ijerph17082852.
95.
go back to reference Jung C, Tepohl L, Tholen R, Beitzel K, Buchmann S, Gottfried T, et al. Rehabilitation following rotator cuff repair: A work of the Commission Rehabilitation of the German Society of Shoulder and Elbow Surgery e.V. (DVSE) in collaboration with the German Association for Physiotherapy (ZVK) e.V., the Association Physical Therapy, Association for Physical Professions (VPT) e.V. and the Section Rehabilitation-Physical Therapy of the German Society for Orthopaedics and Trauma e.V. (DGOU). Obere Extrem. 2018;13(1):45–61.CrossRefPubMedPubMedCentral Jung C, Tepohl L, Tholen R, Beitzel K, Buchmann S, Gottfried T, et al. Rehabilitation following rotator cuff repair: A work of the Commission Rehabilitation of the German Society of Shoulder and Elbow Surgery e.V. (DVSE) in collaboration with the German Association for Physiotherapy (ZVK) e.V., the Association Physical Therapy, Association for Physical Professions (VPT) e.V. and the Section Rehabilitation-Physical Therapy of the German Society for Orthopaedics and Trauma e.V. (DGOU). Obere Extrem. 2018;13(1):45–61.CrossRefPubMedPubMedCentral
96.
go back to reference Sheps DM, Silveira A, Beaupre L, Styles-Tripp F, Balyk R, Lalani A, et al. Early Active Motion Versus Sling Immobilization After Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial. Arthroscopy. 2019;35(3):749–760.e742.CrossRefPubMed Sheps DM, Silveira A, Beaupre L, Styles-Tripp F, Balyk R, Lalani A, et al. Early Active Motion Versus Sling Immobilization After Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial. Arthroscopy. 2019;35(3):749–760.e742.CrossRefPubMed
98.
go back to reference Kang L, Henn RF, Tashjian RZ, Green A. Early outcome of arthroscopic rotator cuff repair: a matched comparison with mini-open rotator cuff repair. Arthroscopy. 2007;23(6):573–82.CrossRefPubMed Kang L, Henn RF, Tashjian RZ, Green A. Early outcome of arthroscopic rotator cuff repair: a matched comparison with mini-open rotator cuff repair. Arthroscopy. 2007;23(6):573–82.CrossRefPubMed
Metadata
Title
Retear rates after rotator cuff surgery: a systematic review and meta-analysis
Authors
Umile Giuseppe Longo
Arianna Carnevale
Ilaria Piergentili
Alessandra Berton
Vincenzo Candela
Emiliano Schena
Vincenzo Denaro
Publication date
01-12-2021
Publisher
BioMed Central
Keyword
Painful Arc
Published in
BMC Musculoskeletal Disorders / Issue 1/2021
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-021-04634-6

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